Results 91 to 100 of about 2,642,890 (372)

Interplay between single-stranded binding proteins on RNA secondary structure

, 2013
RNA protein interactions control the fate of cellular RNAs and play an important role in gene regulation. An interdependency between such interactions allows for the implementation of logic functions in gene regulation.
Bundschuh, Ralf, Lin, Yi-Hsuan
core   +1 more source

The hydration of protein secondary structures

FEBS Letters, 1987
The hydration of the main‐chain carbonyl (CO) groups in proteins have been studied using infra‐red spectroscopy, and computer‐graphics analysis of high resolution protein crystal structures. The IR measurements indicate that the strength of water binding to the CO groups is lower in β‐sheet proteins compared with α‐helical ones. Analysis of the protein
Barlow, D.J., Poole, P.L.
openaire   +2 more sources

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Protein Secondary Structure Prediction

, 2008
{"references": ["Cuff, J. A. and Barton, G.J. \"Evaluation and improvement of multiple\nsequence methods for protein secondary structure prediction. Proteins,\n34, 1999, pp. 508-519.", "Cuff, J.A. and Barton G.J. \"Application of multiple sequence alignment\nprofiles to improve protein secondary structure prediction\" Proteins, 40,\n2000, pp. 502-511.",
Manpreet Singh, Sandhu, Parvinder Singh, Kaur, Reet Kamal   +2 more
openaire   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Improved probability graph model for protein secondary structure prediction

Journal of Hebei University of Science and Technology, 2016
Protein secondary structure is closely related to protein tertiary structure and function, and became a hot topic in bioinformatics. The probability graph model HMM (Hidden Markov model) is an important tool in this field.
Lingqi ZHAO, Lijuan ZHU, Kejing WANG, Xiaoqing DONG, Yi ZHANG   +4 more
doaj   +1 more source

Functional Properties of Protein Hydrolyzate from Ribbon Fish (Lepturacanthus Savala) as Prepared by Enzymatic hydrolysis

International Journal of Food Properties, 2022
Fish protein hydrolyzates (FPH) are breakdown products of hydrolysis and are gaining importance in the field of nutraceuticals and functional foods due to their bioactive properties, high nutritional value, solubility, and digestibility. This study aimed
Undiganalu Gangadharappa Yathisha, Sneha Vaidya, Mamatha Bangera Sheshappa   +2 more
doaj   +1 more source

Multi-S3P: Protein Secondary Structure Prediction With Specialized Multi-Network and Self-Attention-Based Deep Learning Model

IEEE Access, 2023
Protein structure prediction (PSP) is a vital challenge in bioinformatics, structural biology and drug discovery. Protein secondary structure (SS) prediction is critical since three-dimensional (3D) structures are primarily made up of secondary ...
M. M. Mohamed Mufassirin, M. A. Hakim Newton, Julia Rahman, Abdul Sattar   +3 more
doaj   +1 more source

Photoactivation Mechanism, Timing of Protein Secondary Structure Dynamics and Carotenoid Translocation in the Orange Carotenoid Protein

Journal of the American Chemical Society, 2018
The orange carotenoid protein (OCP) is a two-domain photoactive protein that noncovalently binds an echinenone (ECN) carotenoid and mediates photoprotection in cyanobacteria.
P. Konold, I. V. van Stokkum, F. Muzzopappa, Adjélé Wilson, M. Groot, D. Kirilovsky, J. Kennis   +6 more
semanticscholar   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source