Results 21 to 30 of about 1,038,800 (260)

Protein secondary structure prediction (PSSP) using different machine algorithms

open access: yesEgyptian Journal of Medical Human Genetics, 2021
Background The computational biology approach has advanced exponentially in protein secondary structure prediction (PSSP), which is vital for the pharmaceutical industry.
Heba M. Afify   +3 more
doaj   +1 more source

Molecular cloning and analysis of Myc modulator 1 (Mm-1) from Bufo gargarizans (Amphibia: Anura)

open access: yesZoologia (Curitiba), 2010
The protein of Myc modulator 1 (Mm-1) has been reported to repress the transcriptional activity of the proto-oncogene c-Myc in humans. Moreover, it was shown to be the subunit 5 of human prefoldin (PFD).
Ning Wang   +3 more
doaj   +1 more source

Pervasive, conserved secondary structure in highly charged protein regions.

open access: yesPLoS Computational Biology, 2023
Understanding how protein sequences confer function remains a defining challenge in molecular biology. Two approaches have yielded enormous insight yet are often pursued separately: structure-based, where sequence-encoded structures mediate function, and
Catherine G Triandafillou   +3 more
doaj   +1 more source

The hydration of protein secondary structures

open access: yesFEBS Letters, 1987
The hydration of the main‐chain carbonyl (CO) groups in proteins have been studied using infra‐red spectroscopy, and computer‐graphics analysis of high resolution protein crystal structures. The IR measurements indicate that the strength of water binding to the CO groups is lower in β‐sheet proteins compared with α‐helical ones. Analysis of the protein
Barlow, D.J., Poole, P.L.
openaire   +2 more sources

Sample Reduction Strategies for Protein Secondary Structure Prediction

open access: yesApplied Sciences, 2019
Predicting the secondary structure from protein sequence plays a crucial role in estimating the 3D structure, which has applications in drug design and in understanding the function of proteins. As new genes and proteins are discovered, the large size of
Sema Atasever   +3 more
doaj   +1 more source

ISSEC: inferring contacts among protein secondary structure elements using deep object detection

open access: yesBMC Bioinformatics, 2020
Background The formation of contacts among protein secondary structure elements (SSEs) is an important step in protein folding as it determines topology of protein tertiary structure; hence, inferring inter-SSE contacts is crucial to protein structure ...
Qi Zhang   +6 more
doaj   +1 more source

3-State Protein Secondary Structure Prediction based on SCOPe Classes

open access: yesBrazilian Archives of Biology and Technology, 2021
Improving the accuracy of protein secondary structure prediction has been an important task in bioinformatics since it is not only the starting point in obtaining tertiary structure in hierarchical modeling but also enhances sequence analysis and ...
Sema Atasever   +3 more
doaj   +1 more source

PCI-SS: MISO dynamic nonlinear protein secondary structure prediction

open access: yesBMC Bioinformatics, 2009
Background Since the function of a protein is largely dictated by its three dimensional configuration, determining a protein's structure is of fundamental importance to biology.
Aboul-Magd Mohammed O   +2 more
doaj   +1 more source

Extended secondary structures in proteins

open access: yesBiochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2014
Super secondary structures of proteins have been systematically searched and classified, but not enough attention has been devoted to such large edifices beyond the basic identification of secondary structures. The objective of the present study is to show that the association of secondary structures that share some of their backbone residues is a ...
Degrève, Léo   +2 more
openaire   +2 more sources

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