Results 21 to 30 of about 1,014,642 (191)

Improving the accuracy of protein secondary structure prediction using structural alignment [PDF]

open access: yes, 2006
Background: The accuracy of protein secondary structure prediction has steadily improved over the past 30 years. Now many secondary structure prediction methods routinely achieve an accuracy (Q3) of about 75%.
Wishart, D.S.   +3 more
core   +1 more source

Protein secondary structure prediction (PSSP) using different machine algorithms

open access: yesEgyptian Journal of Medical Human Genetics, 2021
Background The computational biology approach has advanced exponentially in protein secondary structure prediction (PSSP), which is vital for the pharmaceutical industry.
Heba M. Afify   +3 more
doaj   +1 more source

A convenient protein library for spectroscopic calibrations

open access: yesComputational and Structural Biotechnology Journal, 2020
While several Raman, CD or FTIR spectral libraries are available for well-characterized proteins of known structure, proteins themselves are usually very difficult to acquire, preventing a convenient calibration of new instruments and new recording ...
Joëlle De Meutter, Erik Goormaghtigh
doaj   +1 more source

Molecular cloning and analysis of Myc modulator 1 (Mm-1) from Bufo gargarizans (Amphibia: Anura)

open access: yesZoologia (Curitiba), 2010
The protein of Myc modulator 1 (Mm-1) has been reported to repress the transcriptional activity of the proto-oncogene c-Myc in humans. Moreover, it was shown to be the subunit 5 of human prefoldin (PFD).
Ning Wang   +3 more
doaj   +1 more source

Pervasive, conserved secondary structure in highly charged protein regions.

open access: yesPLoS Computational Biology, 2023
Understanding how protein sequences confer function remains a defining challenge in molecular biology. Two approaches have yielded enormous insight yet are often pursued separately: structure-based, where sequence-encoded structures mediate function, and
Catherine G Triandafillou   +3 more
doaj   +1 more source

Sample Reduction Strategies for Protein Secondary Structure Prediction

open access: yesApplied Sciences, 2019
Predicting the secondary structure from protein sequence plays a crucial role in estimating the 3D structure, which has applications in drug design and in understanding the function of proteins. As new genes and proteins are discovered, the large size of
Sema Atasever   +3 more
doaj   +1 more source

ISSEC: inferring contacts among protein secondary structure elements using deep object detection

open access: yesBMC Bioinformatics, 2020
Background The formation of contacts among protein secondary structure elements (SSEs) is an important step in protein folding as it determines topology of protein tertiary structure; hence, inferring inter-SSE contacts is crucial to protein structure ...
Qi Zhang   +6 more
doaj   +1 more source

The hydration of protein secondary structures

open access: yesFEBS Letters, 1987
The hydration of the main‐chain carbonyl (CO) groups in proteins have been studied using infra‐red spectroscopy, and computer‐graphics analysis of high resolution protein crystal structures. The IR measurements indicate that the strength of water binding to the CO groups is lower in β‐sheet proteins compared with α‐helical ones. Analysis of the protein
Barlow, D.J., Poole, P.L.
openaire   +2 more sources

A Novel Method for Accurate One-dimensional Protein Structure Prediction Based on Fragment Matching [PDF]

open access: yes, 2010
Motivation: The precise prediction of one-dimensional (1D) protein structure as represented by the protein secondary structure and 1D string of discrete state of dihedral angles (i.e.
Hovmöller, Sven,   +2 more
core   +1 more source

3-State Protein Secondary Structure Prediction based on SCOPe Classes

open access: yesBrazilian Archives of Biology and Technology, 2021
Improving the accuracy of protein secondary structure prediction has been an important task in bioinformatics since it is not only the starting point in obtaining tertiary structure in hierarchical modeling but also enhances sequence analysis and ...
Sema Atasever   +3 more
doaj   +1 more source

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