Results 41 to 50 of about 418,398 (323)

Improved probability graph model for protein secondary structure prediction

open access: yesJournal of Hebei University of Science and Technology, 2016
Protein secondary structure is closely related to protein tertiary structure and function, and became a hot topic in bioinformatics. The probability graph model HMM (Hidden Markov model) is an important tool in this field.
Lingqi ZHAO   +4 more
doaj   +1 more source

Using Deep Learning (CNN, RNN, LSTM, GRU) methods for the prediction of Protein Secondary Structure

open access: yesActa Infologica, 2022
Proteins play a crucial function in the biological processes of living organisms. Knowing the function of the protein offers significant insight into future biological and medical research. Since a protein’s shape determines its function, it is important
Ezgi Çakmak, İhsan Hakan Selvi
doaj   +1 more source

Combining classifiers for protein secondary structure prediction

open access: yes2017 9th International Conference on Computational Intelligence and Communication Networks (CICN), 2017
Protein secondary structure prediction is an important step in estimating the three dimensional structure of proteins. Among the many methods developed for predicting structural properties of proteins, hybrid classifiers and ensembles that combine predictions from several models are shown to improve the accuracy rates. In this paper, we train, optimize
Aydin, Zafer, Uzut, Ommu Gulsum
openaire   +3 more sources

PROTINFO: secondary and tertiary protein structure prediction [PDF]

open access: yesNucleic Acids Research, 2003
Information about the secondary and tertiary structure of a protein sequence can greatly assist biologists in the generation and testing of hypotheses, as well as design of experiments. The PROTINFO server enables users to submit a protein sequence and request a prediction of the three-dimensional (tertiary) structure based on comparative modeling ...
Ling-Hong, Hung, Ram, Samudrala
openaire   +2 more sources

Protein Secondary Structure Prediction Using Dynamic Programming [PDF]

open access: yesActa Biochimica et Biophysica Sinica, 2005
In the present paper, we describe how a directed graph was constructed and then searched for the optimum path using a dynamic programming approach, based on the secondary structure propensity of the protein short sequence derived from a training data set. The protein secondary structure was thus predicted in this way.
Jing, Zhao   +3 more
openaire   +2 more sources

Improved prediction of RNA secondary structure by integrating the free energy model with restraints derived from experimental probing data. [PDF]

open access: yes, 2016
PublishedEvaluation StudiesJournal ArticleResearch Support, Non-U.S. Gov'tRecently, several experimental techniques have emerged for probing RNA structures based on high-throughput sequencing.
Ding, X   +8 more
core   +1 more source

An evolutionary method for learning HMM structure: prediction of protein secondary structure

open access: yesBMC Bioinformatics, 2007
Background The prediction of the secondary structure of proteins is one of the most studied problems in bioinformatics. Despite their success in many problems of biological sequence analysis, Hidden Markov Models (HMMs) have not been used much for this ...
Won Kyoung-Jae   +3 more
doaj   +1 more source

Yetim proteinlerde ikincil yapı öngörüsü için eğitim kümesi indirgeme yöntemleri = Training set reduction methods for single sequence protein secondary structure prediction [PDF]

open access: yes, 2007
Orphan proteins are characterized by the lack of significant sequence similarity to almost all proteins in the database. To infer the functional properties of the orphans, more elaborate techniques that utilize structural information are required.
Altunbasak, Yucel   +7 more
core   +1 more source

Improved Chou-Fasman method for protein secondary structure prediction

open access: yesBMC Bioinformatics, 2006
Background Protein secondary structure prediction is a fundamental and important component in the analytical study of protein structure and functions. The prediction technique has been developed for several decades.
Huang Zhengge, Gu Fei, Chen Hang
doaj   +1 more source

A Simple Comparison between Specific Protein Secondary Structure Prediction Tools

open access: yesTropical Agricultural Research, 2012
A comparative evaluation of five widely used protein secondary structure prediction programs available in World Wide Web was carried out. Secondary structure data of ten proteins containing 190 secondary structure motifs were collected from Protein Data ...
TJ Koswatta   +2 more
doaj   +1 more source

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