Results 71 to 80 of about 418,398 (323)

DSC: public domain protein secondary structure prediction [PDF]

Bioinformatics, 1997
1. DSC has high accuracy. It has a prediction accuracy of 70.1% (per residue) on a standard set of 126 proteins. This percentage was confirmed by the recent CASP2 blind prediction challenge (see below). 2. DSC is based on simple linear statistics. Existing highaccuracy prediction methods are 'black-box' predictors based on complex non-linear statistics
King, Ross D., Saqi, Mansoor, Sayle, Roger, Stern Berg, Michael J E   +3 more
openaire   +3 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

A dynamic Bayesian network approach to protein secondary structure prediction

BMC Bioinformatics, 2008
Background Protein secondary structure prediction method based on probabilistic models such as hidden Markov model (HMM) appeals to many because it provides meaningful information relevant to sequence-structure relationship.
Zhu Huaiqiu, Yao Xin-Qiu, She Zhen-Su
doaj   +1 more source

Secondary Protein Structure Prediction Using Neural Networks [PDF]

, 2022
Sidharth Malhotra, Robin Walters
openalex   +1 more source

MUST-CNN: A Multilayer Shift-and-Stitch Deep Convolutional Architecture for Sequence-based Protein Structure Prediction

, 2016
Predicting protein properties such as solvent accessibility and secondary structure from its primary amino acid sequence is an important task in bioinformatics.
Lanchantin, Jack, Lin, Zeming, Qi, Yanjun   +2 more
core   +1 more source

Abundance of intrinsic disorder in SV-IV, a multifunctional androgen-dependent protein secreted from rat seminal vesicle [PDF]

, 2007
The potent immunomodulatory, anti-inflammatory and procoagulant properties of the protein no. 4 secreted from the rat seminal vesicle epithelium (SV-IV) have been previously found to be modulated by a supramolecular monomer-trimer ...
Ambrosone, Bairoch, Bornberg-Bauer, Bourhis, Cai, Caporale, Cheng, Coeytaux, Csizmók, Doszatányi, Dosztányi, Dunker, Dunker, Dyson, D’Ambrosio, Esposito, Ferron, Gaboriaud, Galzitskaya, Galzitskaya, Galzitskaya, Garbuzynskiy, Harris, Hirose, Ialenti, Kandala, Kyte, Li, Lin, Linding, Linding, Liu, Lupas, MacCallum, McDonald, Metafora, Metafora, Miele, Murzin, Obradovic, Obradovic, Ostrowski, Pan, Prilusky, Quevillon-Cheruel, Radivojac, Ragone, Romero, Romero, Rüping, Shimizu, Shimizu, Sickmeier, Stiuso, Stiuso, Tompa, Tufano, Uversky, Uversky, Vucetic, Ward, Weathers, Weathers, Wolf, Wootton, Wright, Yang   +66 more
core   +3 more sources

Prediction of protein secondary structures from conformational biases [PDF]

Proteins: Structure, Function, and Bioinformatics, 2002
AbstractWe use LINUS (the “Local Independently Nucleated Units of Structure”), a procedure developed by Srinivasan and Rose, to provide a physical interpretation of and predict the secondary structures of proteins. The secondary structure type at a given site is identified by the largest conformational bias during short simulations. We examine the rate
T. X. HOANG, M. CIEPLAK, J. R. BANAVAR, MARITAN, AMOS   +3 more
openaire   +3 more sources

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Prediction of 8-state protein secondary structures by a novel deep learning architecture

BMC Bioinformatics, 2018
Background Protein secondary structure can be regarded as an information bridge that links the primary sequence and tertiary structure. Accurate 8-state secondary structure prediction can significantly give more precise and high resolution on structure ...
Buzhong Zhang, Jinyan Li, Qiang Lü
doaj   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source