Results 221 to 230 of about 4,543,051 (305)

Self‐Assembling Copolymers Encapsulating Single Endothelial Cells Induce Endogenous ECM Deposition and Vascular Regeneration

Advanced Materials, EarlyView.
This study presents the first demonstration of stable sub‐50‐micron single‐cell GPM vesicles fabricated through the intrinsic self‐assembly of an amphiphilic copolymer. Hierarchical assembly of cell containing GPM vesicles into microspheres enable tunable, sustained cell delivery with immune protection.
Viola B. Morris, Sangho Lee, Kalp Soni, Simon He, Matthew Huang, Dandan Chen, Dae Hoon Lee, Kyung Hee Kim, Seonggeon Cho, Laura Pencea, Divit Jain, Young‐Sup Yoon   +11 more
wiley   +1 more source

The conserved two-component systems CutRS and CssRS control the protein secretion stress response in <i>Streptomyces</i>. [PDF]

mBio
McLean TC, Beaton ADM, Holmes NA, Martins C, Saalbach G, Chandra G, Batey SFD, China J, Wilkinson B, Hutchings MI.   +9 more
europepmc   +1 more source

Lab‐in‐a‐Tube System Integrating Hierarchically Wrinkled Electrodes and DNAzyme‐Functionalized Beads for Diagnosis of Clostridioides difficile Infection

Advanced Materials, EarlyView.
The point‐of‐care diagnosis of Clostridioides difficile infection remains challenging due to reliance on slow culture and amplification‐based methods. A lab‐in‐a‐tube electrochemical biosensor integrating DNAzymes, antifouling magnetic beads, and a hierarchically structured flow cell enables amplification‐ and culture‐free detection directly in stool ...
Survanshu Saxena, Soyeon Lee, Youngeun Choi, Jonathan L'Heureux‐Hache, Jiaying Liu, Sadman Sakib, Sara M. Imani, Marek Smieja, Yingfu Li, Todd Hoare, Leyla Soleymani   +10 more
wiley   +1 more source

Two-Step Engineering of Food-Grade <i>Aspergillus oryzae</i> via Endogenous Signal Peptides and Vesicle Trafficking Proteins to Enhance Carrier-Free Protein Secretion. [PDF]

J Fungi (Basel)
Panchanawaporn S, Rattanaphan N, Jeennor S, Anantayanon J, Woraprayote W, Pumpuang L, Karirat T, Prompakdee N, Laoteng K, Chutrakul C.   +9 more
europepmc   +1 more source

Photoacoustic Nanotagging for In Vivo Tracking and Optimization of Macrophage Immunotherapy in Solid Tumors

Advanced Materials, EarlyView.
Macrophage‐based immunotherapy for solid tumors is limited by poor tracking of cell localization and persistence. This study introduces nanotagged macrophages enabling near‐infrared photoacoustic imaging for real‐time monitoring. IFNγ‐conjugated tags enhance antitumor polarization without harming viability.
Seoyoon Song, Melissa Cadena, Myeongsoo Kim, Euisuk Chung, Jeungyoon Lee, Zlata Brushevich, Seonghun Shin, Paul S. Pelkowski, Stanislav Y. Emelianov   +8 more
wiley   +1 more source

Rapid Identification of Superior Endogenous Signal Peptides for Heterologous Protein Secretion by Corynebacterium glutamicum Through Modular Cloning and Automation. [PDF]

Microb Biotechnol
Matamouros S, Tenhaef J, Bida A, Noack S, Bott M.   +4 more
europepmc   +1 more source

Smart Antibacterial Coatings: Harnessing Bacterial Redox Activity for Infection Control

Advanced Materials Interfaces, EarlyView.
In this study, we have shown that ceftazidime‐loaded poly(3,4‐ethylenedioxythiophene) (PEDOT@CAZ) functions as a smart, redox‐responsive antibacterial coating that couples bacterial electrical activity with localized antibiotic delivery. Shewanella oneidensis and Pseudomonas aeruginosa induced distinct redox responses in PEDOT, reflecting their ...
Abdullah, Szymon Smołka, Kamran Ayaz, Sara Shakibania, Sajida Maryam, Taral Patel, Roman Turczyn, Ewa Zabłocka‐Godlewska, Katarzyna Krukiewicz   +8 more
wiley   +1 more source

STAMPS: Signal-peptide Transformer for Augmenting Mammalian Protein Secretion

Gabrielli J, Exposito-Rodriguez M, Briliūtė J, Burrell M, Thom G, Kontoravdi C, Ceroni F.   +6 more
europepmc   +1 more source

Synthesis and Characterization of Biocompatible Manganese‐Doped Titania Nanoparticles and Its Application to Single‐Cell Nanoencapsulation

Advanced Materials Interfaces, EarlyView.
Biocompatible Mn‐doped TiO2 nanozymes integrate TiO2 stability with Mn redox activity, enabling dopamine‐mediated cell‐surface polymerization and single‐cell nanoencapsulation while maintaining high colloidal stability, low ROS generation, and excellent cellular compatibility.
Filip Kozłowski, Nayoung Kim, Hyunwoo Choi, Geoffrey Daniel, Gulaim A. Seisenbaeva, Insung S. Choi, Vadim G. Kessler   +6 more
wiley   +1 more source

YTK Display-and-Secrete: Screening for Optimal Protein Secretion Elements in <i>Saccharomyces cerevisiae</i>. [PDF]

ACS Synth Biol
Kishkevich A, Ciurkot K, Ellis T.
europepmc   +1 more source