Protein-RNA interactions: a structural analysis [PDF]
, 2001 A detailed computational analysis of 32 protein-RNA complexes is presented. A number of physical and chemical properties of the intermolecular interfaces are calculated and compared with those observed in protein-double-stranded DNA and protein-single ...
Daley, DT +9 more
core
Functional and Immunological Relevance of Anaplasma marginale Major Surface Protein 1a Sequence and Structural Analysis. [PDF]
, 2013 Bovine anaplasmosis is caused by cattle infection with the tick-borne bacterium, Anaplasma marginale. The major surface protein 1a (MSP1a) has been used as a genetic marker for identifying A.
Barbosa Ribeiro, Mucio Flavio, M. F. +82 more
core +1 more source
A Protein Sequence Analysis Hardware Accelerator Based on Divergences
International Journal of Reconfigurable Computing, 2012 The Viterbi algorithm is one of the most used dynamic programming algorithms for protein comparison and identification, based on hidden markov Models (HMMs).
Juan Fernando Eusse +3 more
doaj +1 more source
Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega
Molecular Systems Biology, 2011 Multiple sequence alignments are fundamental to many sequence analysis methods. Most alignments are computed using the progressive alignment heuristic. These methods are starting to become a bottleneck in some analysis pipelines when faced with data sets
F. Sievers +11 more
semanticscholar +1 more source
An Entropy-Based Alignment-Free Mathematical Framework for Protein Sequence Similarity Analysis [PDF]
EPJ Web of ConferencesIn this paper, a mathematical, alignment-free framework is proposed for quantifying similarity and dissimilarity among protein sequences using their physicochemical characteristics.
Vijayalakshmi D. +2 more
doaj +1 more source
Analysis of protein chameleon sequence characteristics [PDF]
Bioinformation, 2009 Conversion of local structural state of a protein from an alpha-helix to a beta-strand is usually associated with a major change in the tertiary structure. Similar changes were observed during the self assembly of amyloidogenic proteins to form fibrils, which are implicated in severe diseases conditions, e.g., Alzheimer disease. Studies have emphasized
Ghozlane, Amine +3 more
openaire +3 more sources
An artificial immune system for clustering amino acids in the context of protein function classification [PDF]
, 2009 This paper addresses the classification task of data mining (a form of supervised learning) in the context of an important bioinformatics problem, namely the prediction of protein functions.
Timmis, Jon +5 more
core +1 more source
Studying protein-protein interactions using peptide arrays [PDF]
, 2010 Screening of arrays and libraries of compounds is well-established as a high-throughput method for detecting and analyzing interactions in both biological and chemical systems. Arrays and libraries can be composed from various types of molecules, ranging
Rito, T. +7 more
core +1 more source
Predicting the Specificity- Determining Positions of Receptor Tyrosine Kinase Axl
Frontiers in Molecular Biosciences, 2021 Owing to its clinical significance, modulation of functionally relevant amino acids in protein-protein complexes has attracted a great deal of attention.
Tülay Karakulak +8 more
doaj +1 more source
Nature Protocols, 2013 De novo assembly of RNA-seq data enables researchers to study transcriptomes without the need for a genome sequence; this approach can be usefully applied, for instance, in research on 'non-model organisms' of ecological and evolutionary importance ...
B. Haas +22 more
semanticscholar +1 more source