Comparative statistics for DNA and protein sequences: multiple sequence analysis. [PDF]
Concepts and methods [Karlin, S. & Ghandour, G. (1985) Proc. Natl. Acad. Sci. USA 82, 5800-5804] for the analysis of patterns and relationships are extended to multiple DNA and protein sequences. Functionals include multiple sequence common word occurrence distributions, characterizations of high frequency shared words, and ascertainment of long ...
S, Karlin, G, Ghandour
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CISAPS: Complex Informational Spectrum for the Analysis of Protein Sequences [PDF]
Complex informational spectrum analysis for protein sequences (CISAPS) and its web-based server are developed and presented. As recent studies show, only the use of the absolute spectrum in the analysis of protein sequences using the informational ...
Chrysostomou, Charalambos +5 more
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Taxonomic classification of metagenomic shotgun sequences with CARMA3. [PDF]
Gerlach W, Stoye J. Taxonomic classification of metagenomic shotgun sequences with CARMA3. Nucleic Acids Res. 2011;39(14):e91.The vast majority of microbes are unculturable and thus cannot be sequenced by means of traditional methods.
Jens Stoye +3 more
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MSALigMap (Multiple Sequence Alignment Ligand Mapping) is a tool for mapping active-site amino-acid residues that bind selected ligands on to target protein sequences of interest.
Sameer Hassan +3 more
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Sequence specific interaction of the chromosomal proteins with DNA [PDF]
Calf thymus chromatin was partially deproteinized by 0.6-1 M NaCl extraction. From the shape of the temperature derivative plot of its melting curve, the DNA in each chromatin was resolved into regions of exposed DNA, and DNA still complexed with proteins.
D, Tuan, C, Chetsanga, P M, Doty
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Fast and sensitive multiple alignment of large genomic sequences [PDF]
Brudno M, Chapman M, Göttgens B, Batzoglou S, Morgenstern B. Fast and sensitive multiple alignment of large genomic sequences. BMC Bioinformatics.
Brudno, Michael +13 more
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Modeling structure-function relationships in synthetic DNA sequences using attribute grammars [PDF]
Recognizing that certain biological functions can be associated with specific DNA sequences has led various fields of biology to adopt the notion of the genetic part.
Cai, Yizhi; id_orcid +13 more
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PATTERNFINDER: combined analysis of DNA regulatory sequences and double-helix stability
Background Regulatory regions that function in DNA replication and gene transcription contain specific sequences that bind proteins as well as less-specific sequences in which the double helix is often easy to unwind.
Huang Yanlin, Kowalski David
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Improved Algorithm for Analysis of DNA Sequences Using Multiresolution Transformation
Bioinformatics and genomic signal processing use computational techniques to solve various biological problems. They aim to study the information allied with genetic materials such as the deoxyribonucleic acid (DNA), the ribonucleic acid (RNA), and the ...
T. M. Inbamalar, R. Sivakumar
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Exploration of the Determinants of Protein Structure and Stability by Protein Design [PDF]
Optimization of Rotamers by Iterative Techniques (ORBIT) has been used to calculate novel sequences for several small proteins. A partial sequence design (20 of 28 residues) is described for the zinc finger Zif268 (beta-beta-alpha) motif.
Sarisky, Catherine Ann
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