Results 41 to 50 of about 2,206,167 (301)
FramePlus: aligning DNA to protein sequences
Bioinformatics, 1999 Abstract Motivation: Automated annotation of Expressed Sequence Tags (ESTs) is becoming increasingly important as EST databases continue to grow rapidly. A common approach to annotation is to align the gene fragments against well-documented databases of protein sequences.
Eran Halperin +2 more
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Genome-scale DNA sequence data and the evolutionary history of placental mammals
Data in Brief, 2018 We present a genomic data set comprised of the coding DNA sequences of 5162 loci from 90 vertebrate species, including 82 mammals. The loci were aligned with their protein sequences.
Shaoyuan Wu, Scott Edwards, Liang Liu
doaj +1 more source
A Multimodal Approach towards Genomic Identification of Protein Inhibitors of Uracil-DNA Glycosylase
Viruses, 2023 DNA-mimicking proteins encoded by viruses can modulate processes such as innate cellular immunity. An example is Ung-family uracil-DNA glycosylase inhibition, which prevents Ung-mediated degradation via the stoichiometric protein blockade of the Ung DNA ...
Wael Muselmani +5 more
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rMotifGen: random motif generator for DNA and protein sequences
BMC Bioinformatics, 2007 Background Detection of short, subtle conserved motif regions within a set of related DNA or amino acid sequences can lead to discoveries about important regulatory domains such as transcription factor and DNA binding sites as well as conserved protein ...
Hardin C Timothy, Rouchka Eric C
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Interactions between the R2R3-MYB transcription factor, AtMYB61, and target DNA binding sites. [PDF]
PLoS ONE, 2013 Despite the prominent roles played by R2R3-MYB transcription factors in the regulation of plant gene expression, little is known about the details of how these proteins interact with their DNA targets.
Michael B Prouse, Malcolm M Campbell
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Protein and DNA sequence determinants of thermophilic adaptation
PLoS Computational Biology, 2005 Prokaryotes living at extreme environmental temperatures exhibit pronounced signatures in the amino acid composition of their proteins and nucleotide compositions of their genomes reflective of adaptation to their thermal environments. However, despite significant efforts, the definitive answer of what are the genomic and proteomic compositional ...
Zeldovich K.B. +2 more
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Zhongguo shuxue zazhi, 2022 Objective To investigate the serological and molecular characteristics of HBsAg+ /HBV DNA non-reactive (NR) infections. Methods Samples tested as HBsAg+ and HBV DNA NR were confirmed by individual NAT repeat testing, viral particle concentration by PEG ...
Chunxiang LI +8 more
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Nucleic Acids Research, 1984 Three computer programs are described which may be used to translate a DNA sequence into a protein sequence, back translate the protein sequence into an ambiguous DNA sequence, and then do pattern searching in the ambiguous sequence. The programs are written in the C programming language, have been compiled to run on a microcomputer under the CP/M 80 ...
David W. Mount, Bruce Conrad
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Back-translation for discovering distant protein homologies in the presence of frameshift mutations
Algorithms for Molecular Biology, 2010 Background Frameshift mutations in protein-coding DNA sequences produce a drastic change in the resulting protein sequence, which prevents classic protein alignment methods from revealing the proteins' common origin.
Noé Laurent +2 more
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High-resolution TADs reveal DNA sequences underlying genome organization in flies
Nature Communications, 2017 Despite an abundance of new studies about topologically associating domains (TADs), the role of genetic information in TAD formation is still not fully understood.
Fidel Ramírez +8 more
semanticscholar +1 more source