Results 31 to 40 of about 1,706,932 (293)
A Multimodal Approach towards Genomic Identification of Protein Inhibitors of Uracil-DNA Glycosylase
Viruses, 2023 DNA-mimicking proteins encoded by viruses can modulate processes such as innate cellular immunity. An example is Ung-family uracil-DNA glycosylase inhibition, which prevents Ung-mediated degradation via the stoichiometric protein blockade of the Ung DNA ...
Wael Muselmani +5 more
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rMotifGen: random motif generator for DNA and protein sequences
BMC Bioinformatics, 2007 Background Detection of short, subtle conserved motif regions within a set of related DNA or amino acid sequences can lead to discoveries about important regulatory domains such as transcription factor and DNA binding sites as well as conserved protein ...
Hardin C Timothy, Rouchka Eric C
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Interactions between the R2R3-MYB transcription factor, AtMYB61, and target DNA binding sites. [PDF]
PLoS ONE, 2013 Despite the prominent roles played by R2R3-MYB transcription factors in the regulation of plant gene expression, little is known about the details of how these proteins interact with their DNA targets.
Michael B Prouse, Malcolm M Campbell
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Protein and DNA sequence determinants of thermophilic adaptation
PLoS Computational Biology, 2005 Prokaryotes living at extreme environmental temperatures exhibit pronounced signatures in the amino acid composition of their proteins and nucleotide compositions of their genomes reflective of adaptation to their thermal environments. However, despite significant efforts, the definitive answer of what are the genomic and proteomic compositional ...
Zeldovich K.B. +2 more
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Role of enhancer of zeste homolog 2 polycomb protein and its significance in tumor progression and cell differentiation [PDF]
, 2013 Epigenetics is a branch of genetics that focuses on the heritable changes of DNA or associated proteins, other than DNA sequence variations, which carry information content during cell division [1,2].
Bagella, Luigi Marco, Marchesi, Irene
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Nucleic Acids Research, 1984 Three computer programs are described which may be used to translate a DNA sequence into a protein sequence, back translate the protein sequence into an ambiguous DNA sequence, and then do pattern searching in the ambiguous sequence. The programs are written in the C programming language, have been compiled to run on a microcomputer under the CP/M 80 ...
David W. Mount, Bruce Conrad
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Back-translation for discovering distant protein homologies in the presence of frameshift mutations
Algorithms for Molecular Biology, 2010 Background Frameshift mutations in protein-coding DNA sequences produce a drastic change in the resulting protein sequence, which prevents classic protein alignment methods from revealing the proteins' common origin.
Noé Laurent +2 more
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Zhongguo shuxue zazhi, 2022 Objective To investigate the serological and molecular characteristics of HBsAg+ /HBV DNA non-reactive (NR) infections. Methods Samples tested as HBsAg+ and HBV DNA NR were confirmed by individual NAT repeat testing, viral particle concentration by PEG ...
Chunxiang LI +8 more
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Quadruple context-free L-System mathematical tools as origin of biological evolution [PDF]
, 2010 It is well known that A, T, G, C annealed together early in evolution and the long stretch of DNA was found which ultimately resulted into chromosomes of different organisms.
Arunava Goswami +4 more
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Comparative statistics for DNA and protein sequences: single sequence analysis. [PDF]
Proceedings of the National Academy of Sciences, 1985 Four categories of data representations are used to help interpret structures and similarities of nucleic acid and protein sequences. Statistical significance of the observed relationships revealed by these representations are assessed by a hierarchy of permutation procedures and by comparisons with theoretical random models. Applications are presented
S, Karlin, G, Ghandour
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