Results 31 to 40 of about 1,223,016 (311)
Computational analysis of promoters and DNA-protein interactions [PDF]
, 2009 The investigation of promoter activity and DNA-protein interactions is very important for understanding many crucial cellular processes, including transcription, recombination and replication.
Tomovic, Andrija
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rMotifGen: random motif generator for DNA and protein sequences
BMC Bioinformatics, 2007 Background Detection of short, subtle conserved motif regions within a set of related DNA or amino acid sequences can lead to discoveries about important regulatory domains such as transcription factor and DNA binding sites as well as conserved protein ...
Hardin C Timothy, Rouchka Eric C
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Interactions between the R2R3-MYB transcription factor, AtMYB61, and target DNA binding sites. [PDF]
PLoS ONE, 2013 Despite the prominent roles played by R2R3-MYB transcription factors in the regulation of plant gene expression, little is known about the details of how these proteins interact with their DNA targets.
Michael B Prouse, Malcolm M Campbell
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Protein and DNA sequence determinants of thermophilic adaptation
PLoS Computational Biology, 2005 Prokaryotes living at extreme environmental temperatures exhibit pronounced signatures in the amino acid composition of their proteins and nucleotide compositions of their genomes reflective of adaptation to their thermal environments. However, despite significant efforts, the definitive answer of what are the genomic and proteomic compositional ...
Zeldovich K.B. +2 more
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Nucleic Acids Research, 1984 Three computer programs are described which may be used to translate a DNA sequence into a protein sequence, back translate the protein sequence into an ambiguous DNA sequence, and then do pattern searching in the ambiguous sequence. The programs are written in the C programming language, have been compiled to run on a microcomputer under the CP/M 80 ...
David W. Mount, Bruce Conrad
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Identification of protein coding genes in genomes with statistical functions based on the circular code [PDF]
, 2002 A new statistical approach using functions based on the circular code classifies correctly more than 93 % of bases in protein (coding) genes and non-coding genes of human sequences. Based on this statistical study, a research software called "Analysis of
Lacan, Jérôme +5 more
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Back-translation for discovering distant protein homologies in the presence of frameshift mutations
Algorithms for Molecular Biology, 2010 Background Frameshift mutations in protein-coding DNA sequences produce a drastic change in the resulting protein sequence, which prevents classic protein alignment methods from revealing the proteins' common origin.
Noé Laurent +2 more
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Zhongguo shuxue zazhi, 2022 Objective To investigate the serological and molecular characteristics of HBsAg+ /HBV DNA non-reactive (NR) infections. Methods Samples tested as HBsAg+ and HBV DNA NR were confirmed by individual NAT repeat testing, viral particle concentration by PEG ...
Chunxiang LI +8 more
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Comparative statistics for DNA and protein sequences: single sequence analysis. [PDF]
Proceedings of the National Academy of Sciences, 1985 Four categories of data representations are used to help interpret structures and similarities of nucleic acid and protein sequences. Statistical significance of the observed relationships revealed by these representations are assessed by a hierarchy of permutation procedures and by comparisons with theoretical random models. Applications are presented
S, Karlin, G, Ghandour
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Dynamic distribution of SeqA protein across the chromosome of Escherichia coli K-12 [PDF]
, 2010 The bacterial SeqA protein binds to hemi-methylated GATC sequences that arise in newly synthesized DNA upon passage of the replication machinery. In Escherichia coli K-12, the single replication origin oriC is a well-characterized target for SeqA, which ...
Stephen J. W. Busby +17 more
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