Results 51 to 60 of about 2,206,167 (301)
Comparative statistics for DNA and protein sequences: single sequence analysis. [PDF]
Proceedings of the National Academy of Sciences, 1985 Four categories of data representations are used to help interpret structures and similarities of nucleic acid and protein sequences. Statistical significance of the observed relationships revealed by these representations are assessed by a hierarchy of permutation procedures and by comparisons with theoretical random models. Applications are presented
S, Karlin, G, Ghandour
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Life, 2022 MSALigMap (Multiple Sequence Alignment Ligand Mapping) is a tool for mapping active-site amino-acid residues that bind selected ligands on to target protein sequences of interest.
Sameer Hassan +3 more
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Comparative statistics for DNA and protein sequences: multiple sequence analysis. [PDF]
Proceedings of the National Academy of Sciences, 1985 Concepts and methods [Karlin, S. & Ghandour, G. (1985) Proc. Natl. Acad. Sci. USA 82, 5800-5804] for the analysis of patterns and relationships are extended to multiple DNA and protein sequences. Functionals include multiple sequence common word occurrence distributions, characterizations of high frequency shared words, and ascertainment of long ...
S, Karlin, G, Ghandour
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PATTERNFINDER: combined analysis of DNA regulatory sequences and double-helix stability
BMC Bioinformatics, 2004 Background Regulatory regions that function in DNA replication and gene transcription contain specific sequences that bind proteins as well as less-specific sequences in which the double helix is often easy to unwind.
Huang Yanlin, Kowalski David
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Improved Algorithm for Analysis of DNA Sequences Using Multiresolution Transformation
The Scientific World Journal, 2015 Bioinformatics and genomic signal processing use computational techniques to solve various biological problems. They aim to study the information allied with genetic materials such as the deoxyribonucleic acid (DNA), the ribonucleic acid (RNA), and the ...
T. M. Inbamalar, R. Sivakumar
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H-NS can facilitate specific DNA-binding by RNA polymerase in AT-rich gene regulatory regions.
PLoS Genetics, 2013 Extremely AT-rich DNA sequences present a challenging template for specific recognition by RNA polymerase. In bacteria, this is because the promoter -10 hexamer, the major DNA element recognised by RNA polymerase, is itself AT-rich.
Shivani S Singh, David C Grainger
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Plants, 2022 The studies on the prevalence and genetic diversity of begomoviruses in Saudi Arabia are minimal. In this study, field-grown symptomatic tomato and muskmelon plants were collected, and initially, begomovirus infection was confirmed by the core coat ...
Khalid A. AlHudaib +5 more
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MEME: discovering and analyzing DNA and protein sequence motifs
Nucleic Acids Res., 2006 MEME (Multiple EM for Motif Elicitation) is one of the most widely used tools for searching for novel ‘signals’ in sets of biological sequences. Applications include the discovery of new transcription factor binding sites and protein domains.
T. Bailey +3 more
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Crucial Role of the C-Terminal Domain of Hfq Protein in Genomic Instability
Microorganisms, 2020 G-rich DNA repeats that can form G-quadruplex structures are prevalent in bacterial genomes and are frequently associated with regulatory regions of genes involved in virulence, antigenic variation, and antibiotic resistance.
Virali J. Parekh +5 more
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Sequence specific interaction of the chromosomal proteins with DNA [PDF]
Nucleic Acids Research, 1977 Calf thymus chromatin was partially deproteinized by 0.6-1 M NaCl extraction. From the shape of the temperature derivative plot of its melting curve, the DNA in each chromatin was resolved into regions of exposed DNA, and DNA still complexed with proteins.
D, Tuan, C, Chetsanga, P M, Doty
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