Results 1 to 10 of about 212,467 (329)

Serine/Threonine Protein Kinase STK16 [PDF]

open access: yesInternational Journal of Molecular Sciences, 2019
STK16 (Ser/Thr kinase 16, also known as Krct/PKL12/MPSK1/TSF-1) is a myristoylated and palmitoylated Ser/Thr protein kinase that is ubiquitously expressed and conserved among all eukaryotes. STK16 is distantly related to the other kinases and belongs to the NAK kinase family that has an atypical activation loop architecture.
Xinmiao Ji   +6 more
openaire   +2 more sources

Viral Serine/Threonine Protein Kinases [PDF]

open access: yesJournal of Virology, 2011
ABSTRACT Phosphorylation represents one the most abundant and important posttranslational modifications of proteins, including viral proteins. Virus-encoded serine/threonine protein kinases appear to be a feature that is unique to large DNA viruses.
Thary Jacob   +2 more
openaire   +3 more sources

Mycobacterium tuberculosis Serine/Threonine Protein Kinases [PDF]

open access: yesMicrobiology Spectrum, 2014
ABSTRACT The Mycobacterium tuberculosis genome encodes 11 serine/threonine protein kinases (STPKs). A similar number of two-component systems are also present, indicating that these two signal transduction mechanisms are both important in the adaptation of this bacterial pathogen to its environment. The
Robert N. Husson, Sladjana Prisic
openaire   +3 more sources

The Serine/Threonine Protein Kinase (Akt)/ Protein Kinase B (PkB) Signaling Pathway in Breast Cancer [PDF]

open access: yes, 2020
According to statistical data published in 2019, breast cancer is among the leading causes of death in women worldwide. The serine/threonine kinase (AKT) or protein kinase B (PkB) signaling pathway is activated by phosphorylation processes, which further
Bratu, Ovidiu Gabriel   +8 more
core   +3 more sources

Adenovirus E1A is associated with a serine/threonine protein kinase [PDF]

open access: yesJournal of Virology, 1991
The adenovirus E1A proteins form stable protein complexes with a number of cellular proteins, including cyclin A and the product of the retinoblastoma susceptibility gene. We have been interested in learning about the function of proteins associated with E1A and therefore looked for an enzymatic activity present in E1A complexes.
Ed Harlow, Li-Kuo Su, C. H. Herrmann
openaire   +3 more sources

Hanks-Type Serine/Threonine Protein Kinases and Phosphatases in Bacteria: Roles in Signaling and Adaptation to Various Environments [PDF]

open access: yes, 2018
Reversible phosphorylation is a key mechanism that regulates many cellular processes in prokaryotes and eukaryotes. In prokaryotes, signal transduction includes two-component signaling systems, which involve a membrane sensor histidine kinase and a ...
Janczarek, Monika   +3 more
core   +1 more source

ChemInform Abstract: Substrate and Docking Interactions in Serine/Threonine Protein Kinases [PDF]

open access: yesChemInform, 2007
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
John M. Humphreys   +4 more
openaire   +4 more sources

The serine/threonine kinase MINK1 directly regulates the function of promigratory proteins [PDF]

open access: yesJournal of Cell Science, 2021
AbstractUpregulation of the developmental Wnt/planar cell polarity pathway is observed in many cancers and is associated with cancer development at early and late stages. We recently showed that PRICKLE1 and VANGL2, two core Wnt/PCP components, are overexpressed in triple negative breast cancer and associated with poor prognosis.
Daulat, Avais   +8 more
openaire   +4 more sources

An ABC transporter containing a forkhead-associated domain interacts with a serine-threonine protein kinase and is required for growth of Mycobacterium tuberculosis in mice [PDF]

open access: yes, 2005
Forkhead-associated (FHA) domains are modular phosphopeptide recognition motifs with a striking preference for phosphothreonine-containing epitopes. FHA domains have been best characterized in eukaryotic signaling pathways but have been identified in six
Buxton, RS   +8 more
core   +2 more sources

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