Results 201 to 210 of about 142,215 (332)

FLR-4, a Novel Serine/Threonine Protein Kinase, Regulates Defecation Rhythm inCaenorhabditis elegans [PDF]

, 2005
Masaya Takeuchi, Yuri Kobayashi, Koutarou D. Kimura, Takeshi Ishihara, Isao Katsura   +4 more
openalex   +1 more source

Tau‐targeting nanoparticles for treatment of Alzheimer's disease

Exploration, EarlyView.
Through review of comprehensive literature and research studies, it is found that tau‐targeting nanoparticles may posit beneficial applications to AD therapy. By targeting a key molecular mechanism known to propagate AD pathogenesis, tau‐targeting nanoparticles have the potential to facilitate tau tangle clearance, promote synaptic integrity, and ...
Shreya Pawar, Mohd Ahmar Rauf, Hosam Abdelhady, Arun K. Iyer   +3 more
wiley   +1 more source

A little less aggregation a little more replication: Viral manipulation of stress granules

WIREs RNA, Volume 14, Issue 1, January/February 2023., 2023
Viruses depend entirely on host machinery and therefore aim to conquer the host and defeat its defenses to co‐opt its resources for its own replication. Improved understanding of how viruses counteract host immune responses such as stress granule assembly, detailed here, will inform future antiviral therapeutic strategies.
Matthew J. Brownsword, Nicolas Locker
wiley   +1 more source

Histone Phosphorylation in DNA Damage Response. [PDF]

Int J Mol Sci
Gong P, Guo Z, Wang S, Gao S, Cao Q.
europepmc   +1 more source

Structural basis and prediction of substrate specificity in protein serine/threonine kinases

, 2002
Ross I. Brinkworth, Robert A. Breinl, Boštjan Kobe   +2 more
openalex   +1 more source

EmbR, a regulatory protein with ATPase activity, is a substrate of multiple serine/threonine kinases and phosphatase in Mycobacterium tuberculosis [PDF]

, 2006
Kirti Sharma, Meetu Gupta, A. Krupa, Narayanaswamy Srinivasan, Yogendra Singh   +4 more
openalex   +1 more source

Insulin receptor responsiveness governs TGFβ-induced hepatic stellate cell activation: Insulin resistance instigates liver fibrosis. [PDF]

FASEB J
Lee WH, Bates EA, Kipp ZA, Pauss SN, Martinez GJ, Blair CA, Hinds TD.   +6 more
europepmc   +1 more source

C-terminal truncation and Parkinson's disease-associated mutations down-regulate the protein serine/threonine kinase activity of PTEN-induced kinase-1 [PDF]

, 2006
Chou Hung Sim, Daisy Lio, Su San Mok, Colin L. Masters, Andrew F. Hill, Janetta G. Culvenor, Heung‐Chin Cheng   +6 more
openalex   +1 more source

Berries: Health Effects via Modulation of the Gut Microbiota

Food Frontiers, EarlyView.
ABSTRACT Berries are widely regarded as beneficial foods, rich in polyphenols, flavonoids, and other bioactive compounds that could positively influence human health. Although the gut microbiota plays a crucial role in metabolism and physiology of humans, the interaction between berries and human gut microbiota activity remains unclear.
Manjin Xu, Yunfeng Xu, Lizhi Wu, Huixia Niu, Bei Gao, Kai Sun, Xueqing Li, Mingluan Xing, Zhe Mo, Zhijian Chen, Pengcheng Tu, Xiaoming Lou   +11 more
wiley   +1 more source

Genetic variants in LKB1/AMPK/mTOR pathway are associated with clinical outcomes of chemotherapy in non‐small cell lung cancer

Thoracic Cancer, Volume 13, Issue 23, Page 3322-3330, December 2022., 2022
Alterations in LKB1/AMPK and downstream pathway may modify the response of cancer cells to chemotherapy and clinical outcomes. This study showed that two genetic variants in LKB1/AMPK/mTOR pathway, the AKT1 rs2494750G〉C and TSC1 rs2809244C〉A, were associated with the clinical outcomes after paclitaxel‐cisplatin chemotherapy in patients with advanced ...
Sun Ha Choi, Sook Kyung Do, Shin Yup Lee, Jin Eun Choi, Hyo‐Gyoung Kang, Mi Jeong Hong, Jang Hyuck Lee, Won Kee Lee, Ji Yun Jeong, Kyung Min Shin, Young Woo Do, Eung Bae Lee, Ji Eun Park, Yong Hoon Lee, Hyewon Seo, Seung Soo Yoo, Jaehee Lee, Seung Ick Cha, Chang Ho Kim, Jae Yong Park   +19 more
wiley   +1 more source