Results 201 to 210 of about 133,461 (307)

Extensive phosphorylation with overlapping specificity by Mycobacterium tuberculosis serine/threonine protein kinases [PDF]

, 2010
Sladjana Prišić, Selasi Dankwa, Daniel Schwartz, Michael F. Chou, Jason W. Locasale, Choong‐Min Kang, Guy W. Bemis, George M. Church, Hanno Steen, Robert N. Husson   +9 more
openalex   +1 more source

Investigating the mechanisms of capsicum in age‐related hearing loss: Based on network pharmacology

Eye &ENT Research, EarlyView.
Abstract Background To explore the material basis and action mechanism of the chemical component gene of pepper on presbycusis, and to provide a reference for the traditional Chinese medicine treatment of age‐related hearing loss (ARHL). Methods The chemical composition and action targets of traditional Chinese medicine flavor of pepper were searched ...
Yan Wang, Xiaoyu Song, Fengxin Yang, Huhuifen He, Kun Zhao, Jingjing Qiu, Limei Cui, Qiang Zhang, Limei Liu, Yan Sun   +9 more
wiley   +1 more source

Cracking the Kinase Code: Urinary Biomarkers as Early Alarms for AAA Rupture-A Pilot Study. [PDF]

J Clin Med
Östling EM, Baltrunas T, Grootenboer N, Urbonavicius S.   +3 more
europepmc   +1 more source

Emerging Target Discovery Strategies Drive the Decoding of Therapeutic Power of Natural Products and Further Drug Development: A Case Study of Celastrol

Exploration, EarlyView.
Using celastrol as a case study, this review summarizes various target discovery strategies for natural products, including chemical proteomics, protein microarray, degradation‐based protein profiling, proteome‐wide label‐free approaches, network pharmacology, target‐based drug screening, and indirect strategies.
Yanbei Tu, Guiyu Dai, Yanyan Chen, Lihua Tan, Hanqing Liu, Meiwan Chen   +5 more
wiley   +1 more source

Analysis of phosphomotifs coupled to phosphoproteome and interactome unveils potential human kinase substrate proteins in SARS-CoV-2. [PDF]

Front Cell Infect Microbiol
Shaji V, Rafi A, Ahmed M, Gopalakrishnan AP, Soman S, Revikumar A, Prasad G, Jayanandan A, Raju R.   +8 more
europepmc   +1 more source

Transcriptome analysis provides new insights into the resistance of pepper to Phytophthora capsici infection. [PDF]

BMC Genomics
Shi F, Wang X, Wei M, Zhang X, Wang Z, Lu X, Zou C.   +6 more
europepmc   +1 more source

Eukaryotic-Type Serine/Threonine Protein Kinase StkP Is a Global Regulator of Gene Expression inStreptococcus pneumoniae

, 2007
Lenka Sasková, Linda Nováková, Marek Basler, Pavel Branny   +3 more
openalex   +1 more source

Phosphorylation in the serine/threonine 2609–2647 cluster promotes but is not essential for DNA-dependent protein kinase-mediated nonhomologous end joining in human whole-cell extracts

, 2007
Lawrence F. Povirk, Rui Zhou, Dale A. Ramsden, Susan P. Lees‐Miller, Kristoffer Valerie   +4 more
openalex   +2 more sources

Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy

Ibrain, Volume 11, Issue 1, Page 44-58, Spring 2025.
In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
wiley   +1 more source

Immunohistochemical Study on <i>O</i>-GlcNAcylation in Diabetic Pathologies: Molecular Mechanisms and Implications. [PDF]

Acta Histochem Cytochem
Akimoto Y, Miura Y, Kudo A, Tsumoto H, Fukutomi T, Sugahara D, Arai T, Chiba Y, Kaname S, Yan K, Kawakami H, Endo T.   +11 more
europepmc   +2 more sources