Results 221 to 230 of about 142,215 (332)

Impregnation of mesenchymal stem cell conditioned media with wortmannin enhanced its antiproliferative effect in breast cancer cells via PI3K/Akt/mTOR pathway. [PDF]

BMC Res Notes
Ismail DF, El-Keey MM, Elgendy SM, Hessien M.   +3 more
europepmc   +1 more source

The highly conserved serine threonine kinase StkP of Streptococcus pneumoniae contributes to penicillin susceptibility independently from genes encoding penicillin-binding proteins [PDF]

, 2009
Ricardo Dias, David H Felix, Manuela Caniça, Marie‐Claude Trombe   +3 more
openalex   +1 more source

Dynamic Coupling of MAPK Signaling to the Guanine Nucleotide Exchange Factor GEF-H1. [PDF]

Onco Targets Ther
Leguay K, Kent OA.
europepmc   +1 more source

Smad transcription factors as mediators of 7 transmembrane G protein-coupled receptor signalling. [PDF]

Acta Pharmacol Sin
Chia ZJ, Kumarapperuma H, Zhang R, Little PJ, Kamato D.   +4 more
europepmc   +1 more source

Divergent <i>Plasmodium</i> kinases drive MTOC, kinetochore and axoneme organisation in male gametogenesis. [PDF]

Life Sci Alliance
Yanase R, Zeeshan M, Ferguson DJ, Markus R, Brady D, Bottrill AR, Holder AA, Guttery DS, Tewari R.   +8 more
europepmc   +1 more source

Impacts of Inorganic Arsenic Exposure on Genetic Stability of Human Mesenchymal Stromal Cells

Journal of Applied Toxicology, EarlyView.
ABSTRACT Human mesenchymal stem/stromal cells (hMSCs) can differentiate into mesoderm‐type cells, making them suitable candidates for tissue repair therapies. However, their relatively low frequency in adult tissue necessitates ex vivo expansion prior to regenerative medicine applications, and therefore, long‐term hMSC genetic stability during ...
Marc A. Beal, Melanie Coughlan, Andrée Nunnikhoven, Reena Corbane, Cathy Cummings‐Lorbetskie, Andrea Rowan‐Carroll, Tanvi Sharma, Andrew Williams, Jessie R. Lavoie, Andrew Stalker, Asish Mohapatra, Matthew J. Meier   +11 more
wiley   +1 more source

De-regulation of aurora kinases by oncogenic HPV; implications in cancer development and treatment. [PDF]

Tumour Virus Res
Oladipo KH, Parish JL.
europepmc   +1 more source

Inhibition of Lactate Accumulation via USP38‐Mediated MCT1 Deubiquitination Activates AKT/mTOR Signaling to Mitigate PM2.5‐Induced Lung Injury

Journal of Clinical Laboratory Analysis, EarlyView.
PM2.5 modulates the metabolic pathways of pulmonary epithelial cells, reprogramming their metabolic profile to favor glycolysis and consequently leading to an increase in lactate production. Excess lactate induces apoptosis by inhibiting the AKT/mTOR pathway, offering a novel metabolic perspective on PM2.5‐induced lung injury.
Zixiao Chen, Jing Cao, Shujie Hou, Lingshan Chao, Jingwen Li, Zaixing Jia, Siqin Han, Jialun Chen, Xixin Yan   +8 more
wiley   +1 more source

Comprehensive transcriptome, miRNA and kinome profiling identifies new treatment options for personalized lung cancer therapy. [PDF]

Clin Transl Med
Zhong S, Börgeling Y, Zardo P, Jonigk D, Borlak J.   +4 more
europepmc   +1 more source

Archaeal Eukaryote-Like Serine/Threonine Protein Kinase Interacts with and Phosphorylates a Forkhead-Associated-Domain-Containing Protein [PDF]

, 2010
Bin Wang, Shifan Yang, Lei Zhang, Zheng‐Guo He   +3 more
openalex   +1 more source