Noncanonical Nucleotides in the Genome Around the Maternal‐Zygotic Transition
In this paper, Kazzazi et al. provide a comprehensive review of the dynamics of nonconventional nucleotides in the genome during early developmental stages, hypothesizing a potential role for these nucleotides in the activation of the zygotic genome. ABSTRACT From the very moment of fertilization and throughout development, the cells of animal embryos ...
Latifa Kazzazy+7 more
wiley +1 more source
Analysis of the Plasticity of Circulating Tumor Cells Reveals Differentially Regulated Kinases During the Suspension-to-Adherent Transition. [PDF]
Smit DJ+8 more
europepmc +1 more source
Ferulic acid: extraction, estimation, bioactivity and applications for human health and food
Abstract Ferulic acid ((E)‐3‐(4‐hydroxy‐3‐methoxy‐phenyl) prop‐2‐enoic acid) is a derivative of caffeic acid found in most plants. This abundant phenolic compound exhibits significant antioxidant capacity and a broad spectrum of therapeutic effects, including anti‐inflammatory, antimicrobial, anticancer, antidiabetic, cardiovascular and neuroprotective
Mukul Kumar+13 more
wiley +1 more source
SR Protein Kinase is expressed in <i>Drosophila</i> ovarian germline stem cells but is not essential for their self-renewal. [PDF]
Garrido VE+3 more
europepmc +1 more source
GSK3β phosphorylation catalyzes the aggregation of tau into Alzheimer's disease-like filaments. [PDF]
Chakraborty P+9 more
europepmc +1 more source
Remifentanil Ameliorates Lipopolysaccharide-Induced Neuroinflammation by Regulating the Phosphatidylinositol 3-Kinase/Serine-Threonine Protein Kinase/Hypoxia-Inducible Factor 1 Alpha Pathway. [PDF]
Özcan MS+5 more
europepmc +1 more source
Protein glycosylation in lung cancer from a mass spectrometry perspective
Abstract Lung cancer is a severe disease for which better diagnostic and therapeutic approaches are urgently needed. Increasing evidence implies that aberrant protein glycosylation plays a crucial role in the pathogenesis and progression of lung cancer.
Mirjam Balbisi+2 more
wiley +1 more source
Abstract Immunopeptidomics is becoming an increasingly important field of study. The capability to identify immunopeptides with pivotal roles in the human immune system is essential to shift the current curative medicine towards personalized medicine. Throughout the years, the field has matured, giving insight into the current pitfalls. Nowadays, it is
Daniel Flender+5 more
wiley +1 more source
Unraveling the Mystery of Insulin Resistance: From Principle Mechanistic Insights and Consequences to Therapeutic Interventions. [PDF]
Mir MM+12 more
europepmc +1 more source