Results 241 to 250 of about 212,467 (329)

Protein glycosylation in lung cancer from a mass spectrometry perspective

Mass Spectrometry Reviews, EarlyView.
Abstract Lung cancer is a severe disease for which better diagnostic and therapeutic approaches are urgently needed. Increasing evidence implies that aberrant protein glycosylation plays a crucial role in the pathogenesis and progression of lung cancer.
Mirjam Balbisi, Simon Sugár, Lilla Turiák   +2 more
wiley   +1 more source

Integrin linked kinase and threonine tyrosine kinase modulate TCR signaling. [PDF]

Sci Rep
Caillens V, Boisel E, Ouksel A, Nugue M, Evnouchidou I, Saveanu L.   +5 more
europepmc   +1 more source

Exploring the dynamic landscape of immunopeptidomics: Unravelling posttranslational modifications and navigating bioinformatics terrain

Mass Spectrometry Reviews, EarlyView.
Abstract Immunopeptidomics is becoming an increasingly important field of study. The capability to identify immunopeptides with pivotal roles in the human immune system is essential to shift the current curative medicine towards personalized medicine. Throughout the years, the field has matured, giving insight into the current pitfalls. Nowadays, it is
Daniel Flender, Frédérique Vilenne, Charlotte Adams, Kurt Boonen, Dirk Valkenborg, Geert Baggerman   +5 more
wiley   +1 more source

Cyclin-dependent kinases as mediators of aberrant transcription in prostate cancer. [PDF]

Transl Oncol
Rahman R, Selth LA.
europepmc   +1 more source

Mass Spectrometry Structural Proteomics Enabled by Limited Proteolysis and Cross‐Linking

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The exploration of protein structure and function stands at the forefront of life science and represents an ever‐expanding focus in the development of proteomics. As mass spectrometry (MS) offers readout of protein conformational changes at both the protein and peptide levels, MS‐based structural proteomics is making significant strides in the
Haiyan Lu, Zexin Zhu, Lauren Fields, Hua Zhang, Lingjun Li   +4 more
wiley   +1 more source

Correction: Beylerli et al. MiRNAs as Noninvasive Biomarkers and Therapeutic Agents of Pituitary Adenomas. <i>Int. J. Mol. Sci.</i> 2020, <i>21</i>, 7287. [PDF]

Int J Mol Sci
Beylerli O, Beeraka NM, Gareev I, Pavlov V, Yang G, Liang Y, Aliev G.   +6 more
europepmc   +1 more source

The Hsp90β Isoform: An Attractive Target for Drug Development

Medicinal Research Reviews, EarlyView.
ABSTRACT The beta isoform of 90 kDa heat shock protein (Hsp90β) plays a critical role in maintaining cellular proteostasis by assisting in the folding and refolding of proteins, which is essential for both normal cellular function and stress response.
Subhabrata Chaudhury, Terin D'Amico, Brian S. J. Blagg   +2 more
wiley   +1 more source

GRKs phosphorylate GPCR C-terminal peptides in a hierarchical manner

Löbbert A, Lorz N, Matthees ESF, Rößler P, Hoffmann C, Gossert AD.   +5 more
europepmc   +1 more source

Advances in sulfonyl exchange chemical biology: expanding druggable target space. [PDF]

Chem Sci
Jones LH.
europepmc   +1 more source

Effect of Natural Polyphenols on Breast Cancer Chemoprevention and Treatment

Molecular Nutrition &Food Research, EarlyView.
Effect of Natural Polyphenols on Breast Cancer proliferation and progression. ABSTRACT Breast cancer is the most common type of malignancy among women worldwide. Significant achievements have been made in diagnostic tools and cancer treatments in the past decade; however, the complexity and heterogeneity of certain breast cancer subtypes often lead to ...
Marzia Sichetti, Martina Giuseffi, Eugenia Giglio, Graziella Marino, Marisabel Mecca   +4 more
wiley   +1 more source