Results 251 to 260 of about 212,467 (329)

Bending over backwards for soil emergence: KIPK and KIPK-LIKE1 regulate hypocotyl gravitropic growth. [PDF]

Plant Cell
Kirschner GK.
europepmc   +1 more source

BMP signalling in colorectal cancer: losing the yin to WNTs yang

The Journal of Pathology, EarlyView.
Abstract Colorectal cancer (CRC) is the third most common form of cancer globally, and arises from the hyperproliferation of epithelial cells in the intestine. The architecture and maintenance of these cells is governed by two major signalling pathways working in a counter‐gradient: the stem cell WNT signalling pathway, and the prodifferentiation bone ...
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Comparative Transcriptome Analysis Elucidates the Desiccation Stress Adaptation in <i>Sargassum muticum</i>. [PDF]

Genes (Basel)
Cao W, Zhang M, Wu N, Zheng Y, Li X, Han H, Yu T, Wu Z, Qu P, Li B.   +9 more
europepmc   +1 more source

Recent Progress in Treating Airway Mucus Hypersecretion by Targeting the Epidermal Growth Factor Receptor Signaling Pathway

Pediatric Discovery, EarlyView.
ABSTRACT Asthma, chronic pulmonary obstructive disease (COPD), cystic fibrosis, and acute respiratory infections are severe respiratory conditions that significantly contribute to global morbidity and mortality. Airway mucus hypersecretion is an important common pathophysiological and clinical manifestation of these diseases and is closely associated ...
Yuanyuan Zhang, Fuping Yang, Chunyu Yan, Yu Deng, Enmei Liu   +4 more
wiley   +1 more source

Quantitative proteome and phosphoproteome analyses of streptomyces coelicolor reveal proteins and phosphoproteins modulating differentiation and secondary metabolism [PDF]

González Quiñonez, Nathaly del Valle, Gorshkov, V., Jensen, O. N., Kovalchuk, S., López García, María Teresa (Bio), Manteca Fernández, Ángel, Rioseras de Bustos, Beatriz, Rogowska Wrzesinska, A., Shliaha, P. V., Yagüe Menéndez, Paula   +9 more
core   +1 more source

Key Regulators of Parasite Biology Viewed Through a Post‐Translational Modification Repertoire

PROTEOMICS, EarlyView.
ABSTRACT Parasites are the leading causes of morbidity and mortality in both humans and animals, imposing substantial socioeconomic burdens worldwide. Controlling parasitic diseases has become one of the key issues in achieving “One Health”. Most parasites have sophisticated life cycles exhibiting progressive developmental stages, morphologies, and ...
Naiwen Zhang, Ning Jiang, Qijun Chen
wiley   +1 more source

AQP1 Affects Necroptosis by Targeting RIPK1 in Endothelial Cells of Atherosclerosis. [PDF]

Vasc Health Risk Manag
Wang P, Zheng L, Yang Y, Yue X, Liu J, Fan K, Zhou H, Dong H.   +7 more
europepmc   +1 more source

The Role of Magnesium in Liver Cirrhosis

Portal Hypertension &Cirrhosis, EarlyView.
Magnesium is a vital mineral involved in over 300 enzymatic reactions, crucial for physiological functions. Its deficiency, common in liver cirrhosis patients, correlates with poor outcomes by affecting inflammation, oxidative stress, fibrosis, and immunity. This review explores magnesium's role in cirrhosis and its interaction with disease mechanisms.
Weiye Zeng, Xudan Wang, He Qi, Hongtao Tang, Xun Qi   +4 more
wiley   +1 more source

Microtubule associated serine/threonine kinase-3 inhibits the malignant phenotype of breast cancer by promoting phosphorylation-mediated ubiquitination degradation of yes-associated protein. [PDF]

Breast Cancer Res
Deng N, Kang W, Du J, Rong X, Han Q.
europepmc   +1 more source

Help from the past to cope with the future: Vitis sylvestris as a resource for abiotic stress resilience

PLANTS, PEOPLE, PLANET, EarlyView.
Viticulture is facing increasing challenges due to climate change. The focus on fast growth and sweet berries has come at the expense of stress resilience. Grafting onto Phylloxera‐resistant rootstocks from American species has been the most successful form of ecological pest management.
Samia Daldoul, Islam M. Khattab, Faouzia Hanzouli, Imane Bahlouli, Peter Nick, Ahmed Mliki, Mahmoud Gargouri   +6 more
wiley   +1 more source