Results 251 to 260 of about 142,215 (332)

Key Regulators of Parasite Biology Viewed Through a Post‐Translational Modification Repertoire

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Parasites are the leading causes of morbidity and mortality in both humans and animals, imposing substantial socioeconomic burdens worldwide. Controlling parasitic diseases has become one of the key issues in achieving “One Health”. Most parasites have sophisticated life cycles exhibiting progressive developmental stages, morphologies, and ...
Naiwen Zhang, Ning Jiang, Qijun Chen
wiley   +1 more source

Monitoring Functional Posttranslational Modifications Using a Data‐Driven Proteome Informatic Pipeline

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Posttranslational modifications (PTMs) are of significant interest in molecular biomedicine due to their crucial role in signal transduction across various cellular and organismal processes. Characterizing PTMs, distinguishing between functional and inert modifications, quantifying their occupancies, and understanding PTM crosstalk are ...
Payman Nickchi   +5 more
wiley   +1 more source

A CRISPR-edited isoform of the AMPK kinase LKB1 improves the response to cisplatin in A549 lung cancer cells. [PDF]

open access: yesJ Biol Chem
Severino MB   +13 more
europepmc   +1 more source

The Pseudoenzyme β‐Amylase9 From Arabidopsis Activates α‐Amylase3: A Possible Mechanism to Promote Stress‐Induced Starch Degradation

open access: yesProteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Starch accumulation in plants provides carbon for nighttime use, for regrowth after periods of dormancy, and for times of stress. Both ɑ‐ and β‐amylases (AMYs and BAMs, respectively) catalyze starch hydrolysis, but their functional roles are unclear.
Christopher E. Berndsen   +7 more
wiley   +1 more source

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