Results 211 to 220 of about 4,545,906 (256)

Astrocyte-specific NRCAM deficiency promotes GABAergic synapse pruning to drive central sensitization in bone cancer pain. [PDF]

J Transl Med
Zhang Z, Hou Y, Mao Y, Jiang L, Lu C, Yu J, Huang Y, Xu R, Huang S, Zhang X, Zhu H, Zhang W, Sun Y, Ma Z.   +13 more
europepmc   +1 more source

Engineering MRI-Based Programmable Genetic Sensors Using the MAPPER Platform. [PDF]

Bio Protoc
Chacko AN, He Y, Borg RE, Tang T, Mukherjee A.   +4 more
europepmc   +1 more source

Interplay between the RBP SYNCRIP and RNA methylation in determining sEV miRNA-cargo and function in cell-to-cell communication. [PDF]

Cell Death Dis
Quattrocchi L, Garbo S, Marocco F, Renne MM, Loria M, Pucci M, Costanzo E, Brizzi MF, Fontana S, Battistelli C, Tripodi M.   +10 more
europepmc   +1 more source

Modelling microdomain-mediated protein sorting in immunological signalling

openaire   +1 more source

Prediction of N-terminal protein sorting signals

Current Opinion in Structural Biology, 1997
Recently, neural networks have been applied to a widening range of problems in molecular biology. An area particularly suited to neural-network methods is the identification of protein sorting signals and the prediction of their cleavage sites, as these functional units are encoded by local, linear sequences of amino acids rather than global 3D ...
M Gonzalo Claros, Gunnar von Heijne, Søren Brunak   +2 more
exaly   +4 more sources

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Protein sorting signals and prediction of subcellular localization

Advances in Protein Chemistry, 2000
Kenta Nakai
exaly   +3 more sources

Protein sorting by tyrosine-based signals: adapting to the Ys and wherefores

Trends in Cell Biology, 1997
The endocytic and secretory pathways of eukaryotic cells consist of an array of membrane-bound compartments, each of which contains a characteristic cohort of transmembrane proteins. Understanding how these proteins are targeted to and maintained within their appropriate compartments will be crucial for unravelling the mysteries of organelle biogenesis
Michael Marks
exaly   +3 more sources

Signals for Sorting of Transmembrane Proteins to Endosomes and Lysosomes

Annual Review of Biochemistry, 2003
▪ Abstract  Sorting of transmembrane proteins to endosomes and lysosomes is mediated by signals present within the cytosolic domains of the proteins. Most signals consist of short, linear sequences of amino acid residues. Some signals are referred to as tyrosine-based sorting signals and conform to the NPXY or YXXØ consensus motifs. Other signals known
Juan S, Bonifacino, Linton M, Traub
openaire   +2 more sources

Signal-mediated sorting to the regulated pathway of protein secretion

Annals of Anatomy - Anatomischer Anzeiger, 1999
The existence of specific sorting signals which direct regulated secretory proteins to secretory granules (SGs) was hypothesized two decades ago and since then has been addressed in numerous studies. The discovery that aggregation of regulated secretory proteins is involved in their sorting to SGs questioned the existence of specific sorting signals ...
H H, Gerdes, M M, Glombik
openaire   +2 more sources

A protein complex required for signal-sequence-specific sorting and translocation

Nature, 1994
We have purified a nascent-polypeptide-associated complex (NAC) which prevents short ribosome-associated nascent polypeptides from inappropriate interactions with proteins in the cytosol. NAC binds nascent-polypeptide domains emerging from ribosomes unless a signal peptide is fully exposed. Depletion of cytosolic proteins (including NAC) from ribosomes
B, Wiedmann, H, Sakai, T A, Davis, M, Wiedmann   +3 more
openaire   +2 more sources