Results 81 to 90 of about 1,785,938 (267)

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

FEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda, Sreerama Chaitanya Sridhara, Aura Carreira   +2 more
wiley   +1 more source

Metabolism and Utilization of Non-Protein Nitrogen Sources as Protein Sources in Ruminants

Ruminants possess a unique stomach physiology that allows them to use various forms of dietary nitrogen (N) as protein sources. Ruminant diets often include non-protein nitrogen (NPN) compounds, which, while not proteins themselves, can be converted into proteins by rumen microbes. Consequently, NPN compounds provide an alternative source of ammoniacal
openaire   +2 more sources

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Identifying the optimal ratio from protein foods for protein and nutrient quality in plant-based meals using a non-linear optimization approach

Frontiers in Nutrition
BackgroundPlant-based diets with reduced animal protein intake are increasingly recommended for health and sustainability reasons that have potential implications for nutrient intake, including protein quality.ObjectiveTo develop a non-linear ...
Maryann R. Rolands, Maryann R. Rolands, Fabio Mainardi, Murielle Bochud, Murielle Bochud, Kim-Anne Lê   +5 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Effects of Different Protein Sources on Growth Performance, Muscle Flavor Substances and Quality Structure in Triploid Crucian Carp

Fishes
A 56-day feeding trial was conducted to evaluate the effect of different dietary protein sources on the growth performance, muscle flavor substances, and quality structure of Triploid Crucian Carp.
Liquan Yang, Chenglin Yi, Yujian Mo, Zhimin He, Zhehua Xu, Yimiao He, Yongkang Ouyang, Zhuangwen Mao, Fufa Qu, Jianzhou Tang, Zhen Liu, Zhijia Fang, Shenping Cao   +12 more
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Effects of pork protein ingestion prior to and following performing the army combat fitness test: markers of performance

Journal of the International Society of Sports Nutrition
Background Military personnel engaged in intense activities must consume enough quality protein in their diet to maintain protein balance and promote recovery.
Kelly Hines, Hudson Lee, Sarah E. Johnson, Adriana Gil, Nicolas D. Barringer, Christopher J. Rasmussen, Ryan Sowinski, Drew E. Gonzalez, Richard B. Kreider   +8 more
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Partial substitution of fishmeal with soybean protein-based diets for dourado Salminus brasiliensis

Scientia Agricola
Cost and environmental restrictions limit the use of fishmeal (FM) in aquafeeds and plant protein (PP) sources. Soybean by-products are important alternative; however, their antinutritional factors may reduce fish growth.
Roselany de Oliveira Correa, Fredy Armando Aguilar Aguilar, Thaline Maira Pachelli da Cruz, Rafael Estevan Sabioni, José Eurico Possebon Cyrino   +4 more
doaj   +1 more source