Results 21 to 30 of about 315,126 (303)

Comparative analysis of low-frequency vibrational spectra of native and denatured proteins [PDF]

Известия Саратовского университета. Новая серия: Физика
Background and Objectives: Changes in the secondary and tertiary structures of protein molecules during thermal denaturation lead to changes in their vibrational spectra.
Mankova, Anna A., Brandt, Nikolay Nikolaevich, Chikishev, Andrey Yu.   +2 more
doaj   +1 more source

Protein folding causes an arrest of preprotein translocation into mitochondria in vivo [PDF]

, 1991
With vital yeast cells, a hybrid protein consisting of the amino- terminal third of the precursor to cytochrome b2 and of the entire dihydrofolate reductase was arrested on the import pathway into mitochondria.
Becker, Karin, Guiard, Bernard, Horwich, Arthur, Neupert, Walter, Pfanner, Nikolaus, Schleyer, Manfred, Tropschug, Maximilian, Wienhues, Ulla   +7 more
core   +3 more sources

Interaction Of Calcium Phosphate Nanoparticles With Human Chorionic Gonadotropin Modifies Secondary And Tertiary Protein Structure

Nova Biotechnologica et Chimica, 2015
Calcium phosphate nanoparticles (CaPNP) have good biocompatibility and bioactivity inside human body. In this study, the interaction between CaPNP and human chorionic gonadotropin (hCG) was analyzed to determine the changes in the protein structure in ...
Al-Hakeim Hussein K, Al-Zabeba Rahman S., Grulke Eric, Jaffar Al-Mulla Emad A.   +3 more
doaj   +1 more source

Elucidation of the Correlation between Heme Distortion and Tertiary Structure of the Heme-Binding Pocket Using a Convolutional Neural Network

Biomolecules, 2022
Heme proteins serve diverse and pivotal biological functions. Therefore, clarifying the mechanisms of these diverse functions of heme is a crucial scientific topic. Distortion of heme porphyrin is one of the key factors regulating the chemical properties
Hiroko X. Kondo, Hiroyuki Iizuka, Gen Masumoto, Yuichi Kabaya, Yusuke Kanematsu, Yu Takano   +5 more
doaj   +1 more source

Synthesis and structural characterization of a mimetic membrane-anchored prion protein [PDF]

, 2006
During pathogenesis of transmissible spongiform encephalopathies (TSEs) an abnormal form (PrPSc) of the host encoded prion protein (PrPC) accumulates in insoluble fibrils and plaques. The two forms of PrP appear to have identical covalent structures, but
Andrew C. Gill, Ansari AA, Atvinder K. Rullay, Bertozzi CR, Blanch EW, Borchelt D, Caughey B, Caughey B, Caughey B, Caughey BW, Critchley P, David H. Crout, Eberl H, Ferris A, Georges C, Gill AC, Govaerts C, Haire LF, Harris DA, Hornemann S, Ian D. Sylvester, Imanpreet K. Bath, Kazlauskaite J, Kazlauskaite J, Kenyon GL, King SA, Kirby L, Klein TR, Kocienski PJ, Legname G, Matthew R. Hicks, Mui B, Nosjean O, Pan KM, Poss AJ, Safar J, Seddon AM, Shyng SL, Stahl N, Stahl N, Teresa J. T. Pinheiro, Whitesell JK, Wuthrich K, Zahn R, Zhang ZY   +44 more
core   +1 more source

Effect of bet missense mutations on bromodomain function, inhibitor binding and stability [PDF]

, 2016
Lysine acetylation is an important epigenetic mark regulating gene transcription and chromatin structure. Acetylated lysine residues are specifically recognized by bromodomains, small protein interaction modules that read these modification in a ...
Alessandra, Pasquo, Chiaraluce, Roberta, Consalvi, Valerio, Cynthia, Tallant, Lori, Clorinda, Lori, Laura, Petrosino, Maria, Stefan, Knapp   +7 more
core   +2 more sources

An Algebro-topological description of protein domain structure. [PDF]

PLoS ONE, 2011
The space of possible protein structures appears vast and continuous, and the relationship between primary, secondary and tertiary structure levels is complex.
Robert Clark Penner, Michael Knudsen, Carsten Wiuf, Jørgen Ellegaard Andersen   +3 more
doaj   +1 more source

Bioinformatics Analysis of the NOT5 Gene in Saccharomyces uvarum

Shipin gongye ke-ji, 2022
Objective: In this paper, we obtained the NOT5 gene from Saccharomyces uvarum by transcriptome analysis. Analysis of its biological information can lay the foundation for the later study of the role of the gene.
Shujin DING, Yanping YANG, Ruyou DENG, Fuxian MA, Tuo YIN, Hanyao ZHANG   +5 more
doaj   +1 more source

In-cell NMR characterization of the secondary structure populations of a disordered conformation of α-Synuclein within E. coli cells [PDF]

, 2013
α-Synuclein is a small protein strongly implicated in the pathogenesis of Parkinson’s disease and related neurodegenerative disorders. We report here the use of in-cell NMR spectroscopy to observe directly the structure and dynamics of this protein ...
A Binolfi, Anthony W. P. Fitzpatrick, AS Maltsev, AS Morar, B Fauvet, B Fauvet, BC McNulty, C Camilloni, C Huang, C Lendel, C Li, C Li, CA Waudby, CA Waudby, Carlo Camilloni, Christopher A. Waudby, Christopher M. Dobson, CO Barnes, CR Bodner, CW Bertoncini, D Eliezer, D Sakakibara, DS Biggs, DS Burz, DS Wishart, DS Wishart, E Lescop, EJ De Genst, F Chiti, F Delaglio, F Ferrage, I Bertini, IR Booth, John Christodoulou, JR Allison, K Inomata, KM Slade, KR Metz, Lisa D. Cabrita, Michele Vendruscolo, MM Dedmon, MR Cookson, P Bernadó, P Sarder, P Schanda, PH Weinreb, Piero Andrea Temussi, RC Puetter, SF Gull, T Bartels, TS Ulmer, VN Uversky, VN Uversky, W Wang, WF Vranken, WS Davidson, Z Serber, Z Serber   +57 more
core   +5 more sources

Les mécanismes de repliement des protéines solubles [PDF]

Biotechnologie, Agronomie, Société et Environnement, 2000
Mechanisms of folding of soluble proteins. The function of a protein is carried out by its three-dimensional structure. The rules for translation of the information encoded by DNAinto an amino acid sequence are well known.
Brasseur B., Benhabilès N., Thomas A.
doaj