Results 81 to 90 of about 315,126 (303)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Does a Simple Lattice Protein Folding Model Exhibit Self-Organized Criticality? [PDF]
, 2014 Proteins are known to fold into tertiary structures that determine their functionality in living organisms. However, the way they consistently fold to the same structure is unknown.
Bajracharya, Arun +3 more
core +1 more source
, 2009 When moving from native to light activated bacteriorhodopsin, modification of charge transport consisting of an increase of conductance is correlated to the protein conformational change.
Alfinito, Eleonora, Reggiani, Lino
core +1 more source
Synthesis of Simplified Azasordarin Analogs as Potential Antifungal Agents [PDF]
, 2019 A new series of simplified azasordarin analogs was synthesized using as key steps a Diels–Alder reaction to generate a highly substituted bicyclo[2.2.1]heptane core, followed by a subsequent nitrile alkylation.
Dockendorff, Chris, Wu, Yibiao
core +4 more sources
Protein tertiary structure and the myoglobin phase diagram [PDF]
Scientific Reports, 2019 AbstractWe develop an effective theory approach to investigate the phase properties of globular proteins. Instead of interactions between individual atoms or localized interaction centers, the approach builds directly on the tertiary structure of a protein. As an example we construct the phase diagram of (apo)myoglobin with temperature (T) and acidity (
Alexander Begun +2 more
openaire +2 more sources
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
The denatured state of N-PGK is compact and predominantly disordered [PDF]
, 2009 The Organisation of the structure present in the chemically denatured N-terminal domain of phosphoglycerate kinase (N-PGK) has been determined by paramagnetic relaxation enhancements (PREs) to define the conformational landscape accessible to the domain.
Clarke, A.R. +5 more
core +1 more source
Животновъдни науки, 2022 Fatty acid binding proteins (FABPs) belong to a multigene family of intracellular lipid binding proteins. The aim of the study was to identify the structure and properties of fatty acid binding protein from the liver of Cyrpinus carpio.
Anila Hoda, Valbona Kolaneci
doaj
In-Silico Approaches for Molecular Characterization, Structural Function Prediction and Peptide Toxicity Analysis of the Matrix Protein of Vesicular stomatitis Indiana Virus (VSIV) [PDF]
BIO Web of ConferencesVesicular Stomatitis Indiana Virus (VSIV) is a primary RNA virus studied for its effects in virology and in biotechnology the matrix protein of VSIV is key in linking the viral envelope to the core which is essential role in the assembly and release of ...
S Ramya +3 more
doaj +1 more source
ProKware: integrated software for presenting protein structural properties in protein tertiary structures [PDF]
Nucleic Acids Research, 2006 Protein tertiary structure plays an essential role in deciphering protein functions, especially protein structural properties, including domains, active sites and post-translational modifications. These properties typically yield useful clues for understanding protein functions.
Hung, Jui-Hung +2 more
openaire +2 more sources