Results 11 to 20 of about 3,840,867 (319)
Biomolecules, 2021 Glutathione transferases (GSTs) are the main detoxification enzymes in schistosomes. These parasitic enzymes tend to be upregulated during drug treatment, with Schistosoma haematobium being one of the species that mainly affect humans. There is a lack of
Neo Padi +5 more
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Representativeness of variation benchmark datasets
BMC Bioinformatics, 2018 Background Benchmark datasets are essential for both method development and performance assessment. These datasets have numerous requirements, representativeness being one.
Gerard C. P. Schaafsma, Mauno Vihinen
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CCharPPI web server: computational characterization of protein–protein interactions from structure [PDF]
, 2014 The atomic structures of protein–protein interactions are central to understanding their role in biological systems, and a wide variety of biophysical functions and potentials have been developed for their characterization and the construction of ...
Fernández-Recio, Juan +2 more
core +3 more sources
Highlights in BioScience, 2020 Genetic mutagenesis is a very efficient tool in studying genes function. Because of the great benefits of legumes as human food and animal feed worldwide, we used a model plant Medicago truncatula for identification gene function related to nitrogen ...
Asmaa Hamdy Hassan +2 more
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Recovery of Protein Structure from Contact Maps [PDF]
, 1997 We present an efficient algorithm to recover the three dimensional structure of a protein from its contact map representation. First we show that when a physically realizable map is used as target, our method generates a structure whose contact map is ...
Domany, Eytan +2 more
core +2 more sources
Automated protein structure calculation from NMR data [PDF]
, 2009 Current software is almost at the stage to permit completely automatic structure determination of small proteins of < 15 kDa, from NMR spectra to structure validation with minimal user interaction.
Craven, C.J., Williamson, M.P.
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Network properties of protein structures [PDF]
Physica A, 346/1-2 (2005) pp. 27-33, 2004 Protein structures can be studied as complex networks of interacting amino acids. We study proteins of different structural classes from the network perspective. Our results indicate that proteins, regardless of their structural class, show small-world network property.
arxiv +1 more source
Deriving a mutation index of carcinogenicity using protein structure and protein interfaces [PDF]
, 2014 With the advent of Next Generation Sequencing the identification of mutations in the genomes of healthy and diseased tissues has become commonplace.
A Custodio +71 more
core +4 more sources
The LBFGS Quasi-Newtonian Method for Molecular Modeling Prion AGAAAAGA Amyloid Fibrils [PDF]
, 2012 Experimental X-ray crystallography, NMR (Nuclear Magnetic Resonance) spectroscopy, dual polarization interferometry, etc are indeed very powerful tools to determine the 3-Dimensional structure of a protein (including the membrane protein); theoretical ...
Hou, Yating +4 more
core +3 more sources
WASH interacts with Ku to regulate DNA double-stranded break repair
iScience, 2022 Summary: The Wiskott-Aldrich syndrome protein and SCAR homolog (WASH), an actin nucleation-promoting factor, is present in the nucleus where it regulates gene transcription and maintains nuclear organization.
Tao Wang +9 more
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