Results 11 to 20 of about 2,069,772 (318)
Biomolecules, 2021 Glutathione transferases (GSTs) are the main detoxification enzymes in schistosomes. These parasitic enzymes tend to be upregulated during drug treatment, with Schistosoma haematobium being one of the species that mainly affect humans. There is a lack of
Neo Padi +5 more
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Representativeness of variation benchmark datasets
BMC Bioinformatics, 2018 Background Benchmark datasets are essential for both method development and performance assessment. These datasets have numerous requirements, representativeness being one.
Gerard C. P. Schaafsma, Mauno Vihinen
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Cell-based assays to identify novel retinoprotective agents
MethodsX, 2020 Degeneration of the retina can lead ultimately to devastating irreversible vision loss, such as in inherited retinitis pigmentosa and age-related macular degeneration. Currently there is no cure to prevent retinal degeneration.
Jeanee Bullock +2 more
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Functional properties of individual sub-domains of the fibrin(ogen) αC-domains
BBA Advances, 2023 Background: Fibrinogen is a large polyfunctional plasma protein consisting of a number of structural and functional domains. Among them, two αC-domains, each formed by the amino acid residues Аα392–610, are involved in fibrin polymerization, activation ...
Y.M. Stohnii +10 more
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A structural alignment kernel for protein structures [PDF]
Bioinformatics, 2007 AbstractMotivation: This work aims to develop computational methods to annotate protein structures in an automated fashion. We employ a support vector machine (SVM) classifier to map from a given class of structures to their corresponding structural (SCOP) or functional (Gene Ontology) annotation.
Qiu, Jian +4 more
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Structural Proteins of Reoviruses [PDF]
Journal of Virology, 1968 Polyacrylamide gel electrophoresis of the solubilized proteins from the three serotypes of reovirus revealed that each contained three major and four minor components. Subviral particles were prepared by brief treatment of complete virions with urea.
P C, Loh, A J, Shatkin
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Highlights in BioScience, 2020 Genetic mutagenesis is a very efficient tool in studying genes function. Because of the great benefits of legumes as human food and animal feed worldwide, we used a model plant Medicago truncatula for identification gene function related to nitrogen ...
Asmaa Hamdy Hassan +2 more
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Scientific Reports, 2022 We have recently developed a mouse monoclonal antibody (12–10H) binding to the head domain region in rat P2X4 receptor (rP2X4R, which is crucial for the pathogenesis of neuropathic pain) expressed on the cell with the highest binding affinity (K D = 20 ...
Chinatsu Shinozaki +11 more
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Identification of the Protein Glycation Sites in Human Myoglobin as Rapidly Induced by d-Ribose
Molecules, 2021 Protein glycation is an important protein post-translational modification and is one of the main pathogenesis of diabetic angiopathy. Other than glycated hemoglobin, the protein glycation of other globins such as myoglobin (Mb) is less studied.
Jing-Jing Liu +6 more
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FEBS Open Bio, 2022 Highly pathogenic human coronaviruses (CoV) including SARS‐CoV, MERS‐CoV and SARS‐CoV‐2 have emerged over the past two decades, resulting in infectious disease outbreaks that have greatly affected public health.
Shuyuan Qiao +3 more
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