Results 41 to 50 of about 1,386,749 (339)
Prediction of protein structure [PDF]
Current Biology, 2000 Altschul SF, Madden TL, Schaffer AA, Zhang J, Zhang Z, Miller W, Lipman DJ: Gapped BLAST and PSI-BLAST: a new generation of protein database search programs.Nucleic Acids Res 1997, 25:3389-3402Bowie JU, Eisenberg D: Inverted protein structure prediction.
openaire +2 more sources
Improved protein structure prediction using predicted interresidue orientations
Proceedings of the National Academy of Sciences of the United States of America, 2019 Significance Protein structure prediction is a longstanding challenge in computational biology. Through extension of deep learning-based prediction to interresidue orientations in addition to distances, and the development of a constrained optimization ...
Jianyi Yang +5 more
semanticscholar +1 more source
High‐accuracy protein structure prediction in CASP14
Proteins: Structure, Function, and Bioinformatics, 2021 The application of state‐of‐the‐art deep‐learning approaches to the protein modeling problem has expanded the “high‐accuracy” category in CASP14 to encompass all targets.
J. Pereira +5 more
semanticscholar +1 more source
BMC Bioinformatics, 2020 Background Whenever suitable template structures are not available, usage of fragment-based protein structure prediction becomes the only practical alternative as pure ab initio techniques require massive computational resources even for very small ...
Jad Abbass, Jean-Christophe Nebel
doaj +1 more source
Single-sequence protein structure prediction using supervised transformer protein language models
bioRxiv, 2022 It remains challenging for single-sequence protein structure prediction with AlphaFold2 and other deep learning methods. In this work, we introduce trRosettaX-Single, a novel algorithm for singlesequence protein structure prediction.
Wenkai Wang, Zhenling Peng, Jianyi Yang
semanticscholar +1 more source
PS4: a next-generation dataset for protein single-sequence secondary structure prediction
BioTechniques, 2023 Protein secondary structure prediction is a subproblem of protein folding. A light-weight algorithm capable of accurately predicting secondary structure from only the protein residue sequence could provide useful input for tertiary structure prediction ...
Omar Peracha
doaj +1 more source
Peptide-binding specificity prediction using fine-tuned protein structure prediction networks
bioRxiv, 2022 Peptide binding proteins play key roles in biology, and predicting their binding specificity is a long-standing challenge. While considerable protein structural information is available, the most successful current methods use sequence information alone,
Amir Motmaen +5 more
semanticscholar +1 more source
Naive Prediction of Protein Backbone Phi and Psi Dihedral Angles Using Deep Learning
Molecules, 2023 Protein structure prediction represents a significant challenge in the field of bioinformatics, with the prediction of protein structures using backbone dihedral angles recently achieving significant progress due to the rise of deep neural network ...
Matic Broz, Marko Jukič, Urban Bren
doaj +1 more source
Recent Progress of Protein Tertiary Structure Prediction
MoleculesThe prediction of three-dimensional (3D) protein structure from amino acid sequences has stood as a significant challenge in computational and structural bioinformatics for decades.
Qiqige Wuyun +7 more
doaj +1 more source
The MULTICOM toolbox for protein structure prediction
BMC Bioinformatics, 2012 Background As genome sequencing is becoming routine in biomedical research, the total number of protein sequences is increasing exponentially, recently reaching over 108 million. However, only a tiny portion of these proteins (i.e.
Cheng Jianlin +4 more
doaj +1 more source