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Protein subcellular localization prediction tools [PDF]

open access: yesComputational and Structural Biotechnology Journal
Protein subcellular localization prediction is of great significance in bioinformatics and biological research. Most of the proteins do not have experimentally determined localization information, computational prediction methods and tools have been ...
Maryam Gillani, Gianluca Pollastri
doaj   +5 more sources

Identification of Protein Subcellular Localization With Network and Functional Embeddings [PDF]

open access: yesFrontiers in Genetics, 2021
The functions of proteins are mainly determined by their subcellular localizations in cells. Currently, many computational methods for predicting the subcellular localization of proteins have been proposed.
Xiaoyong Pan   +7 more
doaj   +4 more sources

Green Fluorescent Protein- and Discosoma sp. Red Fluorescent Protein-Tagged Organelle Marker Lines for Protein Subcellular Localization in Rice [PDF]

open access: yesFrontiers in Plant Science, 2019
The subcellular localization of proteins is a fundamental aspect of protein functions. Determining the subcellular localization is important for understanding the biological functions of proteins.
Ziqiang Chen   +14 more
doaj   +4 more sources

CELLO2GO: a web server for protein subCELlular LOcalization prediction with functional gene ontology annotation. [PDF]

open access: yesPLoS ONE, 2014
CELLO2GO (http://cello.life.nctu.edu.tw/cello2go/) is a publicly available, web-based system for screening various properties of a targeted protein and its subcellular localization.
Chin-Sheng Yu   +6 more
doaj   +4 more sources

LocPro: A deep learning-based prediction of protein subcellular localization for promoting multi-directional pharmaceutical research [PDF]

open access: yesJournal of Pharmaceutical Analysis
Drug development encompasses multiple processes, wherein protein subcellular localization is essential. It promotes target identification, treatment development, and the design of drug delivery systems.
Yintao Zhang   +9 more
doaj   +2 more sources

A Novel Protein Subcellular Localization Method With CNN-XGBoost Model for Alzheimer's Disease [PDF]

open access: yesFrontiers in Genetics, 2019
The disorder distribution of protein in the compartment or organelle leads to many human diseases, including neurodegenerative diseases such as Alzheimer's disease.
Long Pang   +4 more
doaj   +2 more sources

Bird Eye View of Protein Subcellular Localization Prediction [PDF]

open access: yesLife, 2020
Proteins are made up of long chain of amino acids that perform a variety of functions in different organisms. The activity of the proteins is determined by the nucleotide sequence of their genes and by its 3D structure.
Ravindra Kumar, Sandeep Kumar Dhanda
doaj   +2 more sources

Automated classification of protein subcellular localization in immunohistochemistry images to reveal biomarkers in colon cancer [PDF]

open access: yesBMC Bioinformatics, 2020
Background Protein biomarkers play important roles in cancer diagnosis. Many efforts have been made on measuring abnormal expression intensity in biological samples to identity cancer types and stages.
Zhen-Zhen Xue   +4 more
doaj   +2 more sources

Predicting human protein subcellular localization by heterogeneous and comprehensive approaches. [PDF]

open access: yesPLoS ONE, 2017
Drug development and investigation of protein function both require an understanding of protein subcellular localization. We developed a system, REALoc, that can predict the subcellular localization of singleplex and multiplex proteins in humans.
Chi-Hua Tung   +3 more
doaj   +2 more sources

Technologies to measure and modulate protein subcellular localization. [PDF]

open access: yesNat Rev Mol Cell Biol
Leineweber W   +4 more
europepmc   +2 more sources

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