Refining protein subcellular localization. [PDF]
PLoS Computational Biology, 2005 The study of protein subcellular localization is important to elucidate protein function. Even in well-studied organisms such as yeast, experimental methods have not been able to provide a full coverage of localization.
Michelle S Scott +3 more
doaj +3 more sources
A review from biological mapping to computation-based subcellular localization
Molecular Therapy: Nucleic Acids, 2023 Subcellular localization is crucial to the study of virus and diseases. Specifically, research on protein subcellular localization can help identify clues between virus and host cells that can aid in the design of targeted drugs.
Jing Li, Quan Zou, Lei Yuan
doaj +2 more sources
Feature Fusion Based SVM Classifier for Protein Subcellular Localization Prediction
Journal of Integrative Bioinformatics, 2016 For the importance of protein subcellular localization in different branch of life science and drug discovery, researchers have focused their attentions on protein subcellular localization prediction.
Rahman Julia +3 more
doaj +2 more sources
Semi-supervised protein subcellular localization [PDF]
BMC Bioinformatics, 2009 Background Protein subcellular localization is concerned with predicting the location of a protein within a cell using computational method. The location information can indicate key functionalities of proteins.
Xue Hong +4 more
doaj +2 more sources
Prediction of protein subcellular localization using support vector machine with the choice of proper kernel [PDF]
BioTechnologia, 2017 The prediction of subcellular locations of proteins can provide useful hints for revealing their functions as well as for understanding the mechanisms of some diseases and, finally, for developing novel drugs.
Al Mehedi Hasan +2 more
doaj +2 more sources
Protocol to determine the subcellular localization of protein interactions in murine keratinocytes [PDF]
STAR Protocols, 2023 Summary: Protein activities and interactions are determined by their subcellular localization. Elucidating the network of protein-protein interactions at a spatial resolution is essential for understanding the complexity of protein functions, their ...
Lisa Müller
doaj +2 more sources
Predicting multiplex subcellular localization of proteins using protein-protein interaction network: a comparative study [PDF]
BMC Bioinformatics, 2012 Background Proteins that interact in vivo tend to reside within the same or "adjacent" subcellular compartments. This observation provides opportunities to reveal protein subcellular localization in the context of the protein-protein interaction (PPI ...
Jiang Jonathan Q, Wu Maoying
doaj +2 more sources
Deep generative model for protein subcellular localization prediction. [PDF]
Brief BioinformYuan GH +8 more
europepmc +2 more sources
Gm-PLoc: A Subcellular Localization Model of Multi-Label Protein Based on GAN and DeepFM
Frontiers in Genetics, 2022 Identifying the subcellular localization of a given protein is an essential part of biological and medical research, since the protein must be localized in the correct organelle to ensure physiological function.
Liwen Wu +14 more
doaj +1 more source
Frontiers in Genetics, 2021 Given the limitation of technologies, the subcellular localizations of proteins are difficult to identify. Predicting the subcellular localization and the intercellular distribution patterns of proteins in accordance with their specific biological roles,
Lei Chen +8 more
doaj +1 more source