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Quantitative protein localization signatures reveal an association between spatial and functional divergences of proteins. [PDF]
PLoS Computational Biology, 2014 Protein subcellular localization is a major determinant of protein function. However, this important protein feature is often described in terms of discrete and qualitative categories of subcellular compartments, and therefore it has limited applications
Lit-Hsin Loo +2 more
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Computational and Structural Biotechnology Journal, 2021 Prediction of protein localization plays an important role in understanding protein function and mechanisms. In this paper, we propose a general deep learning-based localization prediction framework, MULocDeep, which can predict multiple localizations of
Yuexu Jiang +6 more
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Multi-label multi-kernel transfer learning for human protein subcellular localization. [PDF]
PLoS ONE, 2012 Recent years have witnessed much progress in computational modelling for protein subcellular localization. However, the existing sequence-based predictive models demonstrate moderate or unsatisfactory performance, and the gene ontology (GO) based models ...
Suyu Mei
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DBMLoc: a Database of proteins with multiple subcellular localizations
BMC Bioinformatics, 2008 Background Subcellular localization information is one of the key features to protein function research. Locating to a specific subcellular compartment is essential for a protein to function efficiently.
Zhou Yun +4 more
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Protein localization as a principal feature of the etiology and comorbidity of genetic diseases
Molecular Systems Biology, 2011 Proteins targeting the same subcellular localization tend to participate in mutual protein–protein interactions (PPIs) and are often functionally associated. Here, we investigated the relationship between disease‐associated proteins and their subcellular
Solip Park +5 more
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Esub8: A novel tool to predict protein subcellular localizations in eukaryotic organisms
BMC Bioinformatics, 2004 Background Subcellular localization of a new protein sequence is very important and fruitful for understanding its function. As the number of new genomes has dramatically increased over recent years, a reliable and efficient system to predict protein ...
Liu Bing +3 more
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An incremental approach to automated protein localisation [PDF]
, 2008 Tscherepanow M, Jensen N, Kummert F. An incremental approach to automated protein localisation. BMC Bioinformatics. 2008;9(1): 445.Background: The subcellular localisation of proteins in intact living cells is an important means for gaining information ...
Kummert Franz +5 more
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Paeans/subcellular: Subcellular localization
, 2021 First release of protein subcellular location prediction ...
Pan Gaofeng
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Inducible control of subcellular RNA localization using a synthetic protein-RNA aptamer interaction. [PDF]
PLoS ONE, 2012 Evidence is accumulating in support of the functional importance of subcellular RNA localization in diverse biological contexts. In different cell types, distinct RNA localization patterns are frequently observed, and the available data indicate that ...
Brian J Belmont, Jacquin C Niles
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Phytopathology Research, 2023 Geminiviruses are a group of circular single-stranded DNA viruses that cause severe diseases in many crop plants. However, there is still no fluorescent protein tag suitable for labeling viral proteins endogenously due to the limited genomic space and ...
Yaqin Wang +6 more
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