Imbalanced classification for protein subcellular localization with multilabel oversampling. [PDF]
Rana P, Sowmya A, Meijering E, Song Y.
europepmc +1 more source
Sommer B, Kormeier B, Demenkov PS, et al. Subcellular localization charts: a new visual methodology for the semi-automatic localization of protein-related data sets. Journal of Bioinformatics and Computational Biology.
Hofestädt, Ralf +19 more
core +1 more source
From Lab to Landscape: Environmental Biohybrid Robotics for Ecological Futures
This Perspective explores environmental biohybrid robotics, integrating living tissues, microorganisms, and insects for operation in real‐world ecosystems. It traces the leap from laboratory experiments to forests, wetlands, and urban environments and discusses key challenges, development pathways, and opportunities for ecological monitoring and ...
Miriam Filippi
wiley +1 more source
Spatial transcriptomics technologies are becoming increasingly high-resolution, enabling gene expression measurement at the subcellular level. Here, we present subcellular expression localization analysis (ELLA), a statistical framework for modeling ...
Jade Xiaoqing Wang, Xiang Zhou
doaj +1 more source
Protein subcellular localization and functional studies in horticultural research: problems, solutions, and new approaches. [PDF]
Guo Y, Bao Z, Deng Y, Li Y, Wang P.
europepmc +1 more source
An Automated Combination of Kernels for Predicting Protein Subcellular Localization
Protein subcellular localization is a crucial ingredient to many important inferences about cellular processes, including prediction of protein function and protein interactions.We propose a new class of protein sequence kernels which considers all ...
Ong, C. +4 more
core +1 more source
Intelligent Micro/Nanorobots for Targeted Interventional Therapy: From Bench to Clinic
Zirui Zhang et al. reviewed the application and challenges of mobile nanomachines in interventional therapy. By converting exogenous energy, including chemical, magnetic, optical, and ultrasonic sources, into mechanical forces, micro/nanorobots (MNRs) enable precise actuation at unprecedented scales. Evolving far beyond traditional drug delivery, these
Zirui Zhang +5 more
wiley +1 more source
Self-supervised deep learning encodes high-resolution features of protein subcellular localization. [PDF]
Kobayashi H +3 more
europepmc +1 more source
Rab1A Promotes Hepatic Steatosis by Suppressing Mitophagy via the Raf‐1/ERK1/2/PINK1 Signaling Axis
Why does fat accumulate in the liver? Our study reveals Rab1A as the molecular switch that silences the cell's mitochondrial cleanup crew. Turning Rab1A off reactivates mitophagy, clears excess fat, and reverses fatty liver disease in mice—offering a promising new therapeutic target for MASLD, a growing global health challenge.
Li Zhang +9 more
wiley +1 more source
High-throughput Screening of Sequence Elements Associated with RNA Localization
RNA molecules localize to specific subcellular compartments to perform their biological functions correctly. However, the mechanisms underlying RNA transport and subcellular localization remain poorly understood.
Xinquan Zeng +6 more
doaj +1 more source

