Results 1 to 10 of about 895,431 (308)

Advances in protein subunit vaccines against tuberculosis [PDF]

open access: yesFrontiers in Immunology, 2023
Tuberculosis (TB), also known as the “White Plague”, is caused by Mycobacterium tuberculosis (Mtb). Before the COVID-19 epidemic, TB had the highest mortality rate of any single infectious disease.
Ying Zhang   +5 more
doaj   +2 more sources

A Comprehensive Review of the Protein Subunit Vaccines Against COVID-19 [PDF]

open access: yesFrontiers in Microbiology, 2022
Two years after severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), in December 2019, the first infections were identified in Wuhan city of China.
Mohsen Heidary   +7 more
doaj   +2 more sources

Disseminated Herpes Zoster Following Protein Subunit and mRNA COVID-19 Vaccination in Immunocompetent Patients: Report of Two Cases and Literature Review [PDF]

open access: yesMedicina, 2023
Disseminated herpes zoster (DHZ), resulting from the reactivation of the varicella-zoster virus (VZV), typically occurs in immunocompromised persons. To date, only four cases of DHZ following mRNA, viral vector, or inactivated COVID-19 vaccinations have ...
Chia-Shuen Lin, Chung-Hsing Chang
doaj   +2 more sources

ECMpy, a Simplified Workflow for Constructing Enzymatic Constrained Metabolic Network Model

open access: yesBiomolecules, 2022
Genome-scale metabolic models (GEMs) have been widely used for the phenotypic prediction of microorganisms. However, the lack of other constraints in the stoichiometric model often leads to a large metabolic solution space being inaccessible. Inspired by
Zhitao Mao   +6 more
doaj   +1 more source

An Overview of SARS-CoV-2 Etiopathogenesis and Recent Developments in COVID-19 Vaccines

open access: yesBiomolecules, 2023
The Coronavirus disease-2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has significantly impacted the health and socioeconomic status of humans worldwide.
Dona Susan Mathew   +4 more
doaj   +1 more source

Tetravalent SARS-CoV-2 S1 subunit protein vaccination elicits robust humoral and cellular immune responses in SIV-infected rhesus macaque controllers

open access: yesmBio, 2023
The coronavirus disease 2019 (COVID-19) pandemic has highlighted the need for safe and effective vaccines to be rapidly developed and distributed worldwide, especially considering the emergence of new severe acute respiratory syndrome coronavirus 2 (SARS-
Muhammad S. Khan   +14 more
doaj   +1 more source

Immunogenicity and safety of Biological E’s CORBEVAX™ vaccine compared to COVISHIELD™ (ChAdOx1 nCoV-19) vaccine studied in a phase-3, single blind, multicentre, randomized clinical trial

open access: yesHuman Vaccines & Immunotherapeutics, 2023
Optimum formulation of Biological-E’s protein subunit CORBEVAX™ vaccine was selected in phase-1 and -2 studies and found to be safe and immunogenic in healthy adult population.
Subhash Thuluva   +21 more
doaj   +1 more source

Carbohydrate Ligands for COVID-19 Spike Proteins

open access: yesViruses, 2022
An outbreak of SARS-CoV-2 coronavirus (COVID-19) first detected in Wuhan, China, has created a public health emergency all over the world. The pandemic has caused more than 340 million confirmed cases and 5.57 million deaths as of 23 January 2022 ...
Yung-Kuo Lee   +7 more
doaj   +1 more source

The effect of signal pathways on the neural KATP subunits SUR1/Kir6.2 expression induced by Aβ1-42

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2021
Objective To investigate the potential signal transduction mechanism of β⁃amyloid protein1-42 (Aβ1-42) induced up⁃regulation of ATP sensitive potassium channel KATP subunit SUR1/Kir6.2 proteins expression.
LI Yan⁃ju   +4 more
doaj   +1 more source

Self-subunit swapping occurs in another gene type of cobalt nitrile hydratase. [PDF]

open access: yesPLoS ONE, 2012
Self-subunit swapping is one of the post-translational maturation of the cobalt-containing nitrile hydratase (Co-NHase) family of enzymes. All of these NHases possess a gene organization of , which allows the activator protein to easily form a ...
Yi Liu   +5 more
doaj   +1 more source

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