Protein Design is a Key Factor for Subunit-subunit Association [PDF]
Proceedings of the National Academy of Sciences, 1999 Fundamental questions about the role of the quaternary structures are addressed using a statistical mechanics off-lattice model of a dimer protein. The model, in spite of its simplicity, captures key features of the monomer-monomer interactions revealed ...
Carloni, Paolo +2 more
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Advances in protein subunit vaccines against tuberculosis [PDF]
Frontiers in Immunology, 2023 Tuberculosis (TB), also known as the “White Plague”, is caused by Mycobacterium tuberculosis (Mtb). Before the COVID-19 epidemic, TB had the highest mortality rate of any single infectious disease.
Ying Zhang +5 more
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Breaking tolerance in transgenic mice expressing the human TSH receptor A-subunit: thyroiditis, epitope spreading and adjuvant as a 'double edged sword'. [PDF]
PLoS ONE, 2012 Transgenic mice with the human thyrotropin-receptor (TSHR) A-subunit targeted to the thyroid are tolerant of the transgene. In transgenics that express low A-subunit levels (Lo-expressors), regulatory T cell (Treg) depletion using anti-CD25 before ...
Sandra M McLachlan +4 more
doaj +5 more sources
A Comprehensive Review of the Protein Subunit Vaccines Against COVID-19 [PDF]
Frontiers in Microbiology, 2022 Two years after severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), in December 2019, the first infections were identified in Wuhan city of China.
Mohsen Heidary +7 more
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Disseminated Herpes Zoster Following Protein Subunit and mRNA COVID-19 Vaccination in Immunocompetent Patients: Report of Two Cases and Literature Review [PDF]
Medicina, 2023 Disseminated herpes zoster (DHZ), resulting from the reactivation of the varicella-zoster virus (VZV), typically occurs in immunocompromised persons. To date, only four cases of DHZ following mRNA, viral vector, or inactivated COVID-19 vaccinations have ...
Chia-Shuen Lin, Chung-Hsing Chang
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Advances in protein subunit vaccines against H1N1/09 influenza [PDF]
Frontiers in ImmunologyThe A/H1N1pdm09 influenza virus, which caused the 2009 pandemic, has since become a recurring strain in seasonal influenza outbreaks. Given the ongoing threat of influenza, protein subunit vaccines have garnered significant attention for their safety and
Yu Zhang +9 more
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Allotopic Expression of a Gene Encoding FLAG Tagged-subunit 8 of Yeast Mitochondrial ATP Synthase [PDF]
Hayati Journal of Biosciences, 2006 Subunit 8 of yeast mitochondrial ATP synthase is a polypeptide of 48 amino acids encoded by the mitochondrial ATP8 gene. A nuclear version of subunit 8 gene has been designed to encode FLAG tagged-subunit 8 fused with a mitochondrial signal peptide.
I MADE ARTIKA
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An RNA-Scaffold Protein Subunit Vaccine for Nasal Immunization [PDF]
Vaccines, 2023 Developing recombinant proteins as nasal vaccines for inducing systemic and mucosal immunity against respiratory viruses is promising. However, additional adjuvants are required to overcome the low immunogenicity of protein antigens.
Joy-Yan Lam +6 more
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Evaluating passive immunity in piglets from sows vaccinated with a PEDV S protein subunit vaccine [PDF]
Frontiers in Cellular and Infection MicrobiologyPorcine epidemic diarrhea virus (PEDV) is a highly contagious virus that causes severe diarrhea and high mortality in neonatal piglets. Current control measures, such as inactivated and live-attenuated vaccines, have limitations in providing complete ...
Jiajia Liu +13 more
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Case report: Myocarditis following COVID-19 protein subunit vaccination [PDF]
Frontiers in Cardiovascular Medicine, 2022 We report findings in a 34-year-old female patient who presented with fulminant myocarditis 8 days after receiving the first dose of the ZF2001 RBD-subunit vaccine against coronavirus disease 2019 (COVID-19).
Yi-ming Dong +11 more
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