Results 11 to 20 of about 912,209 (260)

Immunogenicity and safety of Biological E’s CORBEVAX™ vaccine compared to COVISHIELD™ (ChAdOx1 nCoV-19) vaccine studied in a phase-3, single blind, multicentre, randomized clinical trial

open access: yesHuman Vaccines & Immunotherapeutics, 2023
Optimum formulation of Biological-E’s protein subunit CORBEVAX™ vaccine was selected in phase-1 and -2 studies and found to be safe and immunogenic in healthy adult population.
Subhash Thuluva   +21 more
doaj   +1 more source

Carbohydrate Ligands for COVID-19 Spike Proteins

open access: yesViruses, 2022
An outbreak of SARS-CoV-2 coronavirus (COVID-19) first detected in Wuhan, China, has created a public health emergency all over the world. The pandemic has caused more than 340 million confirmed cases and 5.57 million deaths as of 23 January 2022 ...
Yung-Kuo Lee   +7 more
doaj   +1 more source

Self-subunit swapping occurs in another gene type of cobalt nitrile hydratase. [PDF]

open access: yesPLoS ONE, 2012
Self-subunit swapping is one of the post-translational maturation of the cobalt-containing nitrile hydratase (Co-NHase) family of enzymes. All of these NHases possess a gene organization of , which allows the activator protein to easily form a ...
Yi Liu   +5 more
doaj   +1 more source

The effect of signal pathways on the neural KATP subunits SUR1/Kir6.2 expression induced by Aβ1-42

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2021
Objective To investigate the potential signal transduction mechanism of β⁃amyloid protein1-42 (Aβ1-42) induced up⁃regulation of ATP sensitive potassium channel KATP subunit SUR1/Kir6.2 proteins expression.
LI Yan⁃ju   +4 more
doaj   +1 more source

Influence of Conformation of M. tuberculosis RNase P Protein Subunit on Its Function. [PDF]

open access: yesPLoS ONE, 2016
RNase P is an essential enzyme that processes 5' end leader sequence of pre-tRNA to generate mature tRNA. The bacterial RNase Ps contain a RNA subunit and one protein subunit, where the RNA subunit contains the catalytic activity.
Alla Singh   +3 more
doaj   +1 more source

Direct Interaction of Avian Cryptochrome 4 with a Cone Specific G-Protein

open access: yesCells, 2022
Background: Night-migratory birds sense the Earth’s magnetic field by an unknown molecular mechanism. Theoretical and experimental evidence support the hypothesis that the light-induced formation of a radical-pair in European robin cryptochrome 4a ...
Katharina Görtemaker   +11 more
doaj   +1 more source

Allotopic Expression of a Gene Encoding FLAG Tagged-subunit 8 of Yeast Mitochondrial ATP Synthase

open access: yesHayati Journal of Biosciences, 2006
Subunit 8 of yeast mitochondrial ATP synthase is a polypeptide of 48 amino acids encoded by the mitochondrial ATP8 gene. A nuclear version of subunit 8 gene has been designed to encode FLAG tagged-subunit 8 fused with a mitochondrial signal peptide.
I MADE ARTIKA
doaj   +3 more sources

Subunit Exchange in Protein Complexes

open access: yesJournal of Molecular Biology, 2018
Over the past 50 years, protein complexes have been studied with techniques such as X-ray crystallography and electron microscopy, generating images which although detailed are static and homogeneous. More recently, limited application of in vivo fluorescence and other techniques has revealed that many complexes previously thought stable and ...
Tusk, S, Delalez, N, Berry, R
openaire   +2 more sources

Structure of the Saccharolobus solfataricus type III-D CRISPR effector

open access: yesCurrent Research in Structural Biology, 2023
CRISPR-Cas is a prokaryotic adaptive immune system, classified into six different types, each characterised by a signature protein. Type III systems, classified based on the presence of a Cas10 subunit, are rather diverse multi-subunit assemblies with a ...
Giuseppe Cannone   +4 more
doaj   +1 more source

Subunit interactions of the Go protein

open access: yesFEBS Letters, 1992
The monoclonal antibody, MONO, recognizes an epitope on the G protein αo‐subunit [van der Voorn et al., submitted] and readily immunoprecipitates heterotrimeric Go proteins from solubilized, crude bovine brain membranes, as well as from a purified bovine brain G protein preparation.
van der Voorn, Loesje   +2 more
openaire   +2 more sources

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