Protein design is a key factor for subunit–subunit association [PDF]
Proceedings of the National Academy of Sciences, 1999 Fundamental questions about role of the quaternary structures are addressed by using a statistical mechanics off-lattice model of a dimer protein. The model, in spite of its simplicity, captures key features of the monomer–monomer interactions revealed by atomic force experiments.
C. CLEMENTI, P. CARLONI, MARITAN, AMOS
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Breaking tolerance in transgenic mice expressing the human TSH receptor A-subunit: thyroiditis, epitope spreading and adjuvant as a 'double edged sword'. [PDF]
PLoS ONE, 2012 Transgenic mice with the human thyrotropin-receptor (TSHR) A-subunit targeted to the thyroid are tolerant of the transgene. In transgenics that express low A-subunit levels (Lo-expressors), regulatory T cell (Treg) depletion using anti-CD25 before ...
Sandra M McLachlan +4 more
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An Overview of SARS-CoV-2 Etiopathogenesis and Recent Developments in COVID-19 Vaccines
Biomolecules, 2023 The Coronavirus disease-2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has significantly impacted the health and socioeconomic status of humans worldwide.
Dona Susan Mathew +4 more
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Carbohydrate Ligands for COVID-19 Spike Proteins
Viruses, 2022 An outbreak of SARS-CoV-2 coronavirus (COVID-19) first detected in Wuhan, China, has created a public health emergency all over the world. The pandemic has caused more than 340 million confirmed cases and 5.57 million deaths as of 23 January 2022 ...
Yung-Kuo Lee +7 more
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The effect of signal pathways on the neural KATP subunits SUR1/Kir6.2 expression induced by Aβ1-42
Chinese Journal of Contemporary Neurology and Neurosurgery, 2021 Objective To investigate the potential signal transduction mechanism of β⁃amyloid protein1-42 (Aβ1-42) induced up⁃regulation of ATP sensitive potassium channel KATP subunit SUR1/Kir6.2 proteins expression.
LI Yan⁃ju +4 more
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Self-subunit swapping occurs in another gene type of cobalt nitrile hydratase. [PDF]
PLoS ONE, 2012 Self-subunit swapping is one of the post-translational maturation of the cobalt-containing nitrile hydratase (Co-NHase) family of enzymes. All of these NHases possess a gene organization of , which allows the activator protein to easily form a ...
Yi Liu +5 more
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Influence of Conformation of M. tuberculosis RNase P Protein Subunit on Its Function. [PDF]
PLoS ONE, 2016 RNase P is an essential enzyme that processes 5' end leader sequence of pre-tRNA to generate mature tRNA. The bacterial RNase Ps contain a RNA subunit and one protein subunit, where the RNA subunit contains the catalytic activity.
Alla Singh +3 more
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Allotopic Expression of a Gene Encoding FLAG Tagged-subunit 8 of Yeast Mitochondrial ATP Synthase
Hayati Journal of Biosciences, 2006 Subunit 8 of yeast mitochondrial ATP synthase is a polypeptide of 48 amino acids encoded by the mitochondrial ATP8 gene. A nuclear version of subunit 8 gene has been designed to encode FLAG tagged-subunit 8 fused with a mitochondrial signal peptide.
I MADE ARTIKA
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Direct Interaction of Avian Cryptochrome 4 with a Cone Specific G-Protein
Cells, 2022 Background: Night-migratory birds sense the Earth’s magnetic field by an unknown molecular mechanism. Theoretical and experimental evidence support the hypothesis that the light-induced formation of a radical-pair in European robin cryptochrome 4a ...
Katharina Görtemaker +11 more
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Determinants of the voltage dependence of G protein modulation within calcium channel β subunits [PDF]
, 2008 CaVβ subunits of voltage-gated calcium channels contain two conserved domains, a src-homology-3 (SH3) domain and a guanylate kinase-like (GK) domain with an intervening HOOK domain. We have shown in a previous study that, although Gβγ-mediated inhibitory
A Hummer +45 more
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