The cDNA and deduced amino acid sequence of the γ subunit of the L-type calcium channel from rabbit skeletal muscle [PDF]
, 1990 Complementary DNAs for the γ subunit of the calcium channel of rabbit skeletal muscle were isolated on the basis of peptide sequences derived from the purified protein.
Biel +30 more
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The yeast F1-ATPase beta subunit precursor contains functionally redundant mitochondrial protein import information [PDF]
, 1987 The NH2 terminus of the yeast F1-ATPase beta subunit precursor directs the import of this protein into mitochondria. To define the functionally important components of this import signal, oligonucleotide-directed mutagenesis was used to introduce a ...
Bedwell, David M. +2 more
core +1 more source
Interaction between the assembly of the ribosomal subunits: Disruption of 40S ribosomal assembly causes accumulation of extra-ribosomal 60S ribosomal protein uL18/L5. [PDF]
PLoS ONE, 2020 Inhibition of the synthesis of an essential ribosomal protein (r-protein) abrogates the assembly of its cognate subunit, while assembly of the other subunit continues.
Nusrat Rahman +2 more
doaj +1 more source
Journal of Biological Chemistry, 1995 Guanine nucleotide-binding protein beta and gamma subunits form a tightly bound complex that can only be separated by denaturation. Assembly of beta and gamma subunits is a complicated process. The beta 1 and gamma 2 subunits can be synthesized in vitro in rabbit reticulocyte lysate and then assembled into dimers, but beta 1 cannot form beta gamma ...
Denise J. Spring +4 more
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How to change the oligomeric state of a circular protein assembly: switch from 11-subunit to 12-subunit TRAP suggests a general mechanism. [PDF]
PLoS ONE, 2011 Many critical cellular functions are performed by multisubunit circular protein oligomers whose internal geometry has evolved to meet functional requirements.
Chao-Sheng Chen +6 more
doaj +1 more source
Subunit composition of minK potassium channels. [PDF]
, 1995 Expression of minK protein in Xenopus oocytes induces a slowly activating, voltage-dependent, potassium-selective current. Point mutations in minK that alter current gating kinetics, ion selectivity, pharmacology, and response to protein kinase C all ...
Goldstein, SA, Wang, KW
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Subunit Exchange in Protein Complexes
Journal of Molecular Biology, 2018 Over the past 50 years, protein complexes have been studied with techniques such as X-ray crystallography and electron microscopy, generating images which although detailed are static and homogeneous. More recently, limited application of in vivo fluorescence and other techniques has revealed that many complexes previously thought stable and ...
Tusk, S, Delalez, N, Berry, R
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The Est3 protein is a subunit of yeast telomerase [PDF]
Current Biology, 2000 EST1, EST2, EST3 and TLC1 function in a single pathway for telomere replication in the yeast Saccharomyces cerevisiae [1] [2], as would be expected if these genes all encode components of the same complex. Est2p, the reverse transcriptase protein subunit, and TLC1, the templating RNA, are subunits of the catalytic core of yeast telomerase [3] [4] [5 ...
Sara K. Evans +3 more
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Mitochondrial Protein Import [PDF]
, 1987 The role of nucleoside triphosphates (NTPs) in mitochondrial protein import was investigated with the precursors of N. crassa ADP/ATP carrier, F1-ATPase subunit β, F0-ATPase subunit 9, and fusion proteins between subunit 9 and mouse dihydrofolate ...
Arends +72 more
core +4 more sources
Modulation of cardiac Ca2+ channels in Xenopus oocytes by protein kinase C [PDF]
, 1992 L-Type calcium channel was expressed in Xenopus laevis oocytes injected with RNAs coding for different cardiac Cu2+ channel subunits, or with total heart RNA.
Biel +54 more
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