Results 1 to 10 of about 8,268,147 (364)
Protein transport by vesicles and tunnels. [PDF]
J Cell Biol, 2019 Palade’s corpus placed small vesicles as the sole means to transport proteins across stable distinct compartments of the secretory pathway. We suggest that cargo, spatial organization of secretory compartments, and the timing of fission of cargo-filled containers dictate the design of transport intermediates that can be vesicles and transient direct ...
Raote I, Malhotra V.
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A unifying mechanism for protein transport through the core bacterial Sec machinery [PDF]
Open Biology, 2023 Encapsulation and compartmentalization are fundamental to the evolution of cellular life, but they also pose a challenge: how to partition the molecules that perform biological functions—the proteins—across impermeable barriers into sub-cellular ...
William J. Allen, Ian Collinson
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New factors for protein transport identified by a genome-wide CRISPRi screen in mammalian cells. [PDF]
J Cell Biol, 2019 Protein and membrane trafficking pathways are critical for cell and tissue homeostasis. Traditional genetic and biochemical approaches have shed light on basic principles underlying these processes.
Bassaganyas L +16 more
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Regulation of Protein Transport Pathways by the Cytosolic Hsp90s [PDF]
Biomolecules, 2022 The highly conserved molecular chaperone heat shock protein 90 (Hsp90) is well-known for maintaining metastable proteins and mediating various aspects of intracellular protein dynamics. Intriguingly, high-throughput interactome studies suggest that Hsp90
Anna G. Mankovich, Brian C. Freeman
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Structural basis for coupling protein transport and N-glycosylation at the mammalian endoplasmic reticulum. [PDF]
Science, 2018 A close-up view of oligosaccharyltransferase Many secretory and membrane proteins are modified through the attachment of sugar chains by N-glycosylation. Such modification is required for correct protein folding, targeting, and functionality.
Braunger K +8 more
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Protein transport in growing and steady-state cilia. [PDF]
Traffic, 2017 Cilia and eukaryotic flagella are threadlike cell extensions with motile and sensory functions. Their assembly requires intraflagellar transport (IFT), a bidirectional motor‐driven transport of protein carriers along the axonemal microtubules.
Lechtreck KF +3 more
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Proteomic screen reveals diverse protein transport between connected neurons in the visual system [PDF]
Cell Reports, 2022 Summary: Intercellular transfer of toxic proteins between neurons is thought to contribute to neurodegenerative disease, but whether direct interneuronal protein transfer occurs in the healthy brain is not clear.
Lucio M. Schiapparelli +10 more
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AtNHX5 and AtNHX6: Roles in protein transport. [PDF]
Plant Signal Behav, 2016 AtNHX5 and AtNHX6, endosomal Na+,K+/H+ antiporters in Arabidopsis, are localized in the Golgi, trans-Golgi network, and prevacuolear compartment. It becomes evident that AtNHX5 and AtNHX6 play an important role in protein transport toward the vacuole ...
Qiu QS.
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Scientific Reports, 2021 Trichoderma reesei is an ascomycete fungus known for its capability to secrete high amounts of extracellular cellulose- and hemicellulose-degrading enzymes. These enzymes are utilized in the production of second-generation biofuels and T.
Sami Havukainen +5 more
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Transport o proteins into mitochondria [PDF]
Current Opinion in Cell Biology, 1989 The transfer of cytoplasmically synthesized precursor proteins into or across the inner mitochondrial membrane is dependent on energization of the membrane. To investigate the role of this energy requirement, a buffer system was developed in which efficient import of ADP/ATP carrier into mitochondria from the receptor-bound state occurred.
Pfanner, Nikolaus, Neupert, Walter
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