Results 11 to 20 of about 1,594,666 (333)
eLife, 2022 Nearly all mitochondrial proteins need to be targeted for import from the cytosol. For the majority, the first port of call is the translocase of the outer membrane (TOM complex), followed by a procession of alternative molecular machines, conducting ...
Holly C Ford +5 more
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Bacterial Signal Peptides- Navigating the Journey of Proteins
Frontiers in Physiology, 2022 In 1971, Blobel proposed the first statement of the Signal Hypothesis which suggested that proteins have amino-terminal sequences that dictate their export and localization in the cell.
Sharbani Kaushik +2 more
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The ESX-1 Substrate PPE68 Has a Key Function in ESX-1-Mediated Secretion in Mycobacterium marinum
mBio, 2022 Mycobacteria use specialized type VII secretion systems (T7SSs) to secrete proteins across their diderm cell envelope. One of the T7SS subtypes, named ESX-1, is a major virulence determinant in pathogenic species such as Mycobacterium tuberculosis and ...
Merel P. M. Damen +7 more
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TooT-T: discrimination of transport proteins from non-transport proteins [PDF]
BMC Bioinformatics, 2020 Abstract Background Membrane transport proteins (transporters) play an essential role in every living cell by transporting hydrophilic molecules across the hydrophobic membranes. While the sequences of many membrane proteins are known, their structure and function is still not well characterized and understood, owing to the immense effort needed to ...
Munira Alballa, Gregory Butler
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Nucleoside Transporter Proteins
Current Vascular Pharmacology, 2009 Concentrative nucleoside transporters (CNT; SLC28) and equilibrative nucleoside transporters (ENT; SLC29) mediate the uptake of natural nucleosides and a variety of nucleoside-derived drugs, mostly used in anticancer therapy. SLC28 and SLC29 families consist in three and four members, respectively, which differ in their substrate selectivity and their ...
F. Javier Casado +2 more
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Molecular Oncology, 2020 Fibroblast growth factor receptor 1 (FGFR1) transmits signals through the plasma membrane regulating essential cellular processes like division, motility, metabolism, and death.
Marta Pozniak +9 more
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Inositol transport proteins [PDF]
FEBS Letters, 2015 The cyclic polyol myo‐inositol is a key molecule in many different metabolic pathways among all organisms; in addition, it is fundamental for osmotic balance in the mammalian brain. This review sums up inositol transporters from eukaryotic organisms, elucidating their vital role in regulating the intracellular distribution and uptake of inositol.
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Mechanistic Regimes of Vibronic Transport in a Heterodimer and the Design Principle of Incoherent Vibronic Transport in Phycobiliproteins [PDF]
, 2018 Following the observation of coherent oscillations in non-linear spectra of photosynthetic pigment protein complexes, particularly phycobilliprotein such as PC645, coherent vibronic transport has been suggested as a design principle for novel light ...
Aspuru-Guzik, Alan +4 more
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The Role of Light–Dark Regulation of the Chloroplast ATP Synthase
Frontiers in Plant Science, 2017 The chloroplast ATP synthase catalyzes the light-driven synthesis of ATP and is activated in the light and inactivated in the dark by redox-modulation through the thioredoxin system.
Kaori Kohzuma +11 more
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Systemic Long-Distance Signaling and Communication Between Rootstock and Scion in Grafted Vegetables
Frontiers in Plant Science, 2020 Grafting is widely used in fruit, vegetable, and flower propagation to improve biotic and abiotic stress resistance, yield, and quality. At present, the systemic changes caused by grafting, as well as the mechanisms and effects of long-distance signal ...
Xiaohong Lu +5 more
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