Results 251 to 260 of about 6,396,996 (306)

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

open access: yesFEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph   +7 more
wiley   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

open access: yesFEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

open access: yesFEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda   +4 more
wiley   +1 more source
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Protein Transport into Chloroplasts

Annual Review of Plant Biology, 2010
Most proteins in chloroplasts are encoded by the nuclear genome and synthesized as precursors with N-terminal targeting signals called transit peptides. Novel machinery has evolved to specifically import these proteins from the cytosol into chloroplasts.
Hsou-Min Li
exaly   +3 more sources

Zinc Transporter Proteins

Neurochemical Research, 2017
Zinc, which is involved in the structure of all enzyme classes, is a micro nutrient element and necessary for growth and development. The ability of zinc to function without causing toxic effects is depends on the protection of its homeostasis. Zinc transporter proteins are responsible for keeping zinc at certain concentrations.
Abdulkerim Kasim, Baltaci, Kemal, Yuce
openaire   +2 more sources

Nucleoside Transporter Proteins

Current Vascular Pharmacology, 2009
Concentrative nucleoside transporters (CNT; SLC28) and equilibrative nucleoside transporters (ENT; SLC29) mediate the uptake of natural nucleosides and a variety of nucleoside-derived drugs, mostly used in anticancer therapy. SLC28 and SLC29 families consist in three and four members, respectively, which differ in their substrate selectivity and their ...
Molina-Arcas M   +2 more
openaire   +3 more sources

Membrane Transport of Proteins

Nature New Biology, 1972
FACILITATED diffusion of small organic molecules across cell membranes is thought to be carrier-mediated in part because the process displays reaction kinetics. Models describing carrier transport assume that the transported molecule is associated with the membrane, reacting presumably with membrane proteins, and is then moved across the barrier.
C, Liebow, S S, Rothman
openaire   +2 more sources

Transport Proteins

Science Signaling, 2013
Animated lessons describe the classes of transport proteins and illustrate mechanisms of transport.
openaire   +2 more sources

Transport of Proteins into Mitochondria

1984
There is still much that is obscure concerning the transport of proteins into or through the mitochondrial membrane systems. In addition, as pointed out previously, it is unlikely that the details of the process are the same for proteins destined for different compartments of the organelle. A brief summary of the process for matrix proteins might be as
S, Doonan   +4 more
openaire   +2 more sources

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