Results 41 to 50 of about 8,268,147 (364)

Protein transport into peroxisomes: Knowns and unknowns

open access: yesBioessays, 2017
Peroxisomal matrix proteins are synthesized on cytosolic ribosomes and rapidly transported into the organelle by a complex machinery. The data gathered in recent years suggest that this machinery operates through a syringe‐like mechanism, in which the ...
T. Francisco   +5 more
semanticscholar   +1 more source

Endogenous and Exogenous Regulatory Signaling in the Secretory Pathway: Role of Golgi Signaling Molecules in Cancer

open access: yesFrontiers in Cell and Developmental Biology, 2022
The biosynthetic transport route that constitutes the secretory pathway plays a fundamental role in the cell, providing to the synthesis and transport of around one third of human proteins and most lipids.
Simona Del Giudice   +5 more
doaj   +1 more source

Conversion of the coprogen transport protein FhuE and the ferrioxamine B transport protein FoxA into ferrichrome transport proteins [PDF]

open access: yesFEMS Microbiology Letters, 1998
The FhuA protein of Escherichia coli K-12 transports ferrichrome and the structurally related antibiotic albomycin across the outer membrane and serves as a receptor for the phages T1, T5, and phi 80 and for colicin M. In this paper, we show that chimeric proteins consisting of the central part of FhuA and the N- and C-terminal parts of FhuE (coprogen ...
Helmut Killmann, Volkmar Braun
openaire   +3 more sources

Dual roles of an Arabidopsis ESCRT component FREE1 in regulating vacuolar protein transport and autophagic degradation

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2015
Significance Macroautophagy (hereafter as autophagy) involves the delivery of cytosolic materials via autophagosome upon its fusion with the endosome and lysosome/vacuole.
Caiji Gao   +9 more
semanticscholar   +1 more source

In vivo experiments do not support the charge zipper model for Tat translocase assembly

open access: yeseLife, 2017
The twin-arginine translocase (Tat) transports folded proteins across the bacterial cytoplasmic membrane and the plant thylakoid membrane. The Tat translocation site is formed by substrate-triggered oligomerization of the protein TatA.
Felicity Alcock   +3 more
doaj   +1 more source

Quantitative analysis of intra-Golgi transport reveals inter-cisternal exchange for all cargo [PDF]

open access: yes, 2013
The mechanisms controlling the transport of proteins across the Golgi stack of mammalian and plant cells is the subject of intense debate, with two models, cisternal progression and inter-cisternal exchange, emerging as major contenders. A variety of transport experiments have claimed support for each of these models.
arxiv   +1 more source

Landscape of nuclear transport receptor cargo specificity

open access: yesMolecular Systems Biology, 2017
Nuclear transport receptors (NTRs) recognize localization signals of cargos to facilitate their passage across the central channel of nuclear pore complexes (NPCs).
Marie‐Therese Mackmull   +7 more
doaj   +1 more source

Independent SE(3)-Equivariant Models for End-to-End Rigid Protein Docking [PDF]

open access: yesSpotlight at ICLR 2022: International Conference on Learning Representations, 2021
Protein complex formation is a central problem in biology, being involved in most of the cell's processes, and essential for applications, e.g. drug design or protein engineering. We tackle rigid body protein-protein docking, i.e., computationally predicting the 3D structure of a protein-protein complex from the individual unbound structures, assuming ...
arxiv  

Persistent homology analysis of protein structure, flexibility and folding [PDF]

open access: yesInternational Journal for Numerical Methods in Biomedical Engineering, 30, 814-844 (2014), 2014
Proteins are the most important biomolecules for living organisms. The understanding of protein structure, function, dynamics and transport is one of most challenging tasks in biological science. In the present work, persistent homology is, for the first time, introduced for extracting molecular topological fingerprints (MTFs) based on the persistence ...
arxiv   +1 more source

CLC transport proteins in plants [PDF]

open access: yesFEBS Letters, 2009
Other CLC homologues have been cloned in Arabidopsis, tobacco, rice and soybean.
Zifarelli G, Pusch M
openaire   +5 more sources

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