Results 11 to 20 of about 30,230 (147)

A RP-UFLC Assay for Protein Tyrosine Phosphatases: Focus on Protein Tyrosine Phosphatase Non-Receptor Type 2 (PTPN2) [PDF]

open access: yesScientific Reports, 2015
AbstractProtein tyrosine phosphatases (PTPs) are involved in numerous signaling pathways and dysfunctions of certain of these enzymes have been linked to several human diseases including cancer and autoimmune diseases. PTPN2 is a PTP mainly expressed in hematopoietic cells and involved in growth factor and JAK/STAT signaling pathways.
Duval, Romain   +9 more
openaire   +3 more sources

PTPN6 (protein tyrosine phosphatase, non-receptor type 6) [PDF]

open access: yesAtlas of Genetics and Cytogenetics in Oncology and Haematology, 2013
Review on PTPN6 (protein tyrosine phosphatase, non-receptor type 6), with data on DNA, on the protein encoded, and where the gene is implicated.
A. Beghini, F. Lazzaroni
openaire   +3 more sources

PTPN11 (protein tyrosine phosphatase, non-receptor type, 11) [PDF]

open access: yesAtlas of Genetics and Cytogenetics in Oncology and Haematology, 2011
Review on PTPN11 (protein tyrosine phosphatase, non-receptor type, 11), with data on DNA, on the protein encoded, and where the gene is implicated.
M Tartaglia, BD Gelb
openaire   +1 more source

Dimerization of Receptor Protein-Tyrosine Phosphatase alpha in living cells

open access: yesBMC Cell Biology, 2001
Background Dimerization is an important regulatory mechanism of single membrane-spanning receptors. For instance, activation of receptor protein-tyrosine kinases (RPTKs) involves dimerization. Structural, functional and biochemical studies suggested that
Gadella Theodorus WJ   +6 more
doaj   +1 more source

Immune checkpoint PTPN2 predicts prognosis and immunotherapy response in human cancers

open access: yesHeliyon, 2023
Background: PTPN2, a member of the non-receptor protein tyrosine phosphatases family, holds a crucial role in tumorigenesis and cancer immunotherapy. However, most studies on the role of PTPN2 in cancer are limited to specific cancer types.
Xiaolong Tang, Xue Sui, Yongshuo Liu
doaj   +1 more source

Pan-cancer analysis revealing that PTPN2 is an indicator of risk stratification for acute myeloid leukemia

open access: yesScientific Reports, 2023
The non-receptor protein tyrosine phosphatases gene family (PTPNs) is involved in the tumorigenesis and development of many cancers, but the role of PTPNs in acute myeloid leukemia (AML) remains unclear. After a comprehensive evaluation on the expression
Xuanyu Wang   +9 more
doaj   +1 more source

PTPN14 (protein tyrosine phosphatase, non-receptor type 14) [PDF]

open access: yesAtlas of Genetics and Cytogenetics in Oncology and Haematology, 2013
Review on PTPN14 (protein tyrosine phosphatase, non-receptor type 14), with data on DNA, on the protein encoded, and where the gene is implicated.
Hauschild, N, Belle, L, Khew-Goodall, Y
openaire   +2 more sources

Molecular biology of the cell

open access: yesJournal of Education, Health and Sport, 2022
The book is intended for students studying medical and biological specialties.     CHAPTER I. EPIGENETICS INTRODUCTION The science of epigenetics looks at the mechanisms of molecular modifications of histones and DNA that can regulate gene ...
Sergey Dolomatov   +2 more
doaj   +1 more source

PTPN9 (protein tyrosine phosphatase, non-receptor type 9) [PDF]

open access: yesAtlas of Genetics and Cytogenetics in Oncology and Haematology, 2018
Review on PTPN9, with data on DNA, on the protein encoded, and where the gene is implicated.
Nyesiga, Barnabas   +1 more
openaire   +2 more sources

Protein tyrosine phosphatase PTPN1 modulates cell growth and associates with poor outcome in human neuroblastoma

open access: yesDiagnostic Pathology, 2019
Background Protein tyrosine phosphatases (PTPs) regulate neuronal differentiation and survival, but their expression patterns and functions in human neuroblastoma (NB) are scarcely known.
Caroline E. Nunes-Xavier   +7 more
doaj   +1 more source

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