Results 21 to 30 of about 30,230 (147)

PTPN1 (protein tyrosine phosphatase, non-receptor type 1) [PDF]

Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2012
Review on PTPN1 (protein tyrosine phosphatase, non-receptor type 1), with data on DNA, on the protein encoded, and where the gene is implicated.
Leuzzi, G, Calderone, A, Castagnoli, L
openaire   +2 more sources

PTPN7 (protein tyrosine phosphatase, non-receptor type 7) [PDF]

Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011
Review on PTPN7 (protein tyrosine phosphatase, non-receptor type 7), with data on DNA, on the protein encoded, and where the gene is implicated.
Fridberg, Marie, Tassidis, Helena, Gjörloff Wingren, Anette   +2 more
openaire   +3 more sources

Essential Tyrosine Residues for Interaction of the Non-receptor Protein-tyrosine Phosphatase PTP1B with N-cadherin [PDF]

Journal of Biological Chemistry, 2001
Expression of a dominant-negative, catalytically inactive form of the nonreceptor protein-tyrosine phosphatase PTP1B in L-cells constitutively expressing N-cadherin results in loss of N-cadherin-mediated cell-cell adhesion. PTP1B interacts directly with the cytoplasmic domain of N-cadherin, and this association is regulated by phosphorylation of ...
J, Rhee, J, Lilien, J, Balsamo
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SOX2 promotes resistance of melanoma with PD-L1 high expression to T-cell-mediated cytotoxicity that can be reversed by SAHA

Journal for ImmunoTherapy of Cancer, 2020
Background Immune checkpoint inhibitors (ICIs) induce better tumor regression in melanoma with programmed cell death 1 ligand 1 (PD-L1) high expression, but there has been an upsurge of failed responses.
Dong Yang, Chunyan Li, Yuhong Chen, Yun Huang, Xuan Li, Zhiming Li, Ruiyan Wu, Caiqin Wang, Jian Xiao, Xuemin Wang, Pengfei Kong, Jianghua Cao, Fuxue Huang, Zhiling Li, Hailiang Zhang, Jia Mai, Gongkan Feng, Rong Deng, Xiaofeng Zhu   +18 more
doaj   +1 more source

The expression patterns and the diagnostic/prognostic roles of PTPN family members in digestive tract cancers

Cancer Cell International, 2020
Background Non-receptor protein tyrosine phosphatases (PTPNs) are a set of enzymes involved in the tyrosyl phosphorylation. The present study intended to clarify the associations between the expression patterns of PTPN family members, and diagnosis as ...
Jing Chen, Xu Zhao, Yuan Yuan, Jing-Jing Jing   +3 more
doaj   +1 more source

Unraveling protein networks with power graph analysis.

PLoS Computational Biology, 2008
Networks play a crucial role in computational biology, yet their analysis and representation is still an open problem. Power Graph Analysis is a lossless transformation of biological networks into a compact, less redundant representation, exploiting the ...
Loïc Royer, Matthias Reimann, Bill Andreopoulos, Michael Schroeder   +3 more
doaj   +1 more source

Genetic Variants in Protein Tyrosine Phosphatase Non-Receptor Type 23 Are Responsible for Mesiodens Formation

Biology, 2023
A mesiodens is a supernumerary tooth located in the midline of the premaxilla. To investigate the genetic cause of mesiodens, clinical and radiographic examination were performed on 23 family members of a two-generation Hmong family. Whole exome sequencing (WES) or Sanger sequencing were performed in 22 family members and two unrelated Thai patients ...
Ploy Adisornkanj, Rajit Chanprasit, Steven Eliason, Juan M. Fons, Worrachet Intachai, Sissades Tongsima, Bjorn Olsen, Stefan T. Arold, Chumpol Ngamphiw, Brad A. Amendt, Abigail S. Tucker, Piranit Kantaputra   +11 more
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Protein tyrosine phosphatase non-receptor type 14 is a novel sperm-motility biomarker [PDF]

Journal of Assisted Reproduction and Genetics, 2011
To understand the molecular basis of sperm-motility and to identify related novel motility biomarkers.Two-dimensional electrophoresis (2DE) followed by Reverse-phase-nano-high-performance liquid chromatography-electrospray ionization tandem mass spectrometry (RP-nano-HPLC-ESI-MS/MS) were applied to establish the human sperm proteome.
Hsin-Chih Albert, Chao, Chia-Ling, Chung, Hsien-An, Pan, Pao-Chi, Liao, Pao-Lin, Kuo, Chao-Chin, Hsu   +5 more
openaire   +2 more sources

The role for protein tyrosine phosphatase non-receptor type 22 in regulating intestinal homeostasis [PDF]

United European Gastroenterology Journal, 2015
Inflammatory bowel disease represents a chronic intestinal inflammation. Recent knowledge suggests a crucial role for genetic, immunological and bacterial factors in inflammatory bowel disease pathogenesis. Variations within the gene locus encoding PTPN22 have been associated with inflammatory bowel disease. PTPN22 is critically involved in controlling
Spalinger Marianne, Scharl Michael
openaire   +4 more sources

PTPN21 Overexpression Promotes Osteogenic and Adipogenic Differentiation of Bone Marrow-Derived Mesenchymal Stem Cells but Inhibits the Immunosuppressive Function

Stem Cells International, 2019
Protein tyrosine phosphatases (PTPs) act as key regulators in various cellular processes such as proliferation, differentiation, and migration. Our previous research demonstrated that non-receptor-typed PTP21 (PTPN21), a member of the PTP family, played ...
Huafang Wang, Xiaohang Ye, Haowen Xiao, Ni Zhu, Cong Wei, Xiang Sun, Limengmeng Wang, Binsheng Wang, Xiaohong Yu, Xiaoyu Lai, Shan Fu, He Huang   +11 more
doaj   +1 more source