Results 31 to 40 of about 385,069 (262)

Proteinases in the joint: clinical relevance of proteinases in joint destruction [PDF]

open access: yesArthritis Research & Therapy, 2007
Proteinases are involved in essential steps in cartilage and bone homeostasis. Consequently, efforts have been made to establish their potential role in the pathology of rheumatic conditions such as rheumatoid arthritis, osteoarthritis and spondyloarthritis.
Rengel, Yvonne   +2 more
openaire   +3 more sources

Airway Mycosis and the Regulation of Type 2 Immunity

open access: yesJournal of Fungi, 2020
Filamentous fungi of the Aspergillus genus and others have long been linked to the induction of type 2 immunity that underlies IgE-mediated hypersensitivity responses.
John Morgan Knight   +6 more
doaj   +1 more source

Porphyromonas gingivalis laboratory strains and clinical isolates exhibit different distribution of cell surface and secreted gingipains

open access: yesJournal of Oral Microbiology, 2021
Background: The cell-surface cysteine proteinases RgpA, RgpB (Arg-gingipain), and Kgp (Lys-gingipain) are major virulence factors of P. gingivalis, a keystone pathogen in the development of destructive periodontal disease.
Christine A. Seers   +4 more
doaj   +1 more source

Potyviral NIa Proteinase, a Proteinase with Novel Deoxyribonuclease Activity [PDF]

open access: yesJournal of Biological Chemistry, 2004
The NIa proteinase from pepper vein banding virus (PVBV) is a sequence-specific proteinase required for processing of viral polyprotein in the cytoplasm. It accumulates in the nucleus of the infected plant cell and forms inclusion bodies. The function of this protein in the nucleus is not clear.
Anindya, Roy, Savithri, Handanahal S
openaire   +4 more sources

Analyses of MMP20 Missense Mutations in Two Families with Hypomaturation Amelogenesis Imperfecta

open access: yesFrontiers in Physiology, 2017
Amelogenesis imperfecta is a group of rare inherited disorders that affect tooth enamel formation, quantitatively and/or qualitatively. The aim of this study was to identify the genetic etiologies of two families presenting with hypomaturation ...
Jung-Wook Kim   +11 more
doaj   +1 more source

Characterization of lactococci isolated from homemade kefir [PDF]

open access: yesArchives of Biological Sciences, 2007
Five bacteriocin-producing lactococci isolates from traditionally prepared kefir were determined as Lactococcus lactis subsp. lactis. The analyzed isolates showed different plasmid profiles and no cross inhibition between them was detected.
Kojić M.   +4 more
doaj   +1 more source

Cysteine proteinases and cystatins [PDF]

open access: yesBrazilian Archives of Biology and Technology, 2003
This review describeds the definition, localization, functions and examples of cysteine proteinases and their protein inhibitors in vertebrate, non-vertebrate animals and plants. These inhibitors are related with defense mechanisms of plant against pests.
Oliveira, Adeliana S.   +2 more
openaire   +5 more sources

Pathogenicity and virulence of Streptococcus pneumoniae: Cutting to the chase on proteases

open access: yesVirulence, 2021
Bacterial proteases and peptidases are integral to cell physiology and stability, and their necessity in Streptococcus pneumoniae is no exception. Protein cleavage and processing mechanisms within the bacterial cell serve to ensure that the cell lives ...
Mary E. Marquart
doaj   +1 more source

Ubiquitin, a central component of selective cytoplasmic proteolysis, is linked to proteins residing at the locus of non-selective proteolysis, the vacuole [PDF]

open access: yes, 1992
Ubiquitin, an evolutionary highly conserved protein, is known to be involved in selective proteolysis in the cytoplasm. Here we show that ubiquitin-protein conjugates are also found in the yeast vacuole.
Achstetter   +35 more
core   +3 more sources

Viral cysteine proteinases [PDF]

open access: yesPerspectives in Drug Discovery and Design, 1996
Dozens of novel cysteine proteinases have been identified in positive single-stranded RNA viruses and, for the first time, in large double-stranded DNA viruses. The majority of these proteins are distantly related to papain or chymotrypsin and may be direct descendants of primordial proteolytic enzymes.
Alexander E. Gorbalenya   +2 more
openaire   +3 more sources

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