Advanced Functional Materials, EarlyView.A multivalent antiviral platform based on honeycomb‐shaped DNA nanostructures (HC–Urumin) is developed to enhance the potency and breadth of the host defense peptide Urumin. Through spatially patterned trimeric presentation, HC–Urumin disrupts influenza A virus entry, improves cell viability, and reduces disease severity in vivo‐offering a modular and ...
Saurabh Umrao +11 more
wiley +1 more source
Optimizing Nucleic Acid Extraction from Extended Bovine Semen for Endemic and High-Consequence Pathogens. [PDF]
Animals (Basel)Zimmerman A +3 more
europepmc +1 more source
Plasma levels of Human Granulocytic Elastase-alpha-Proteinase Inhibitor Complex (E-alpha1PI) in Leukemia [PDF]
, 1984 Hiller, E., Jochum, Marianne
core
Advanced Functional Materials, EarlyView.A bimetallic Mn–Ca nanoreactor (MCC) is developed as a non‐nucleotide STING nanoagonist for cancer metalloimmunotherapy. MCC induces Ca2+ overload and hydroxyl radical generation, resulting in mitochondrial damage and mtDNA release. The released mtDNA cooperates with Mn2+ to robustly activate cGAS–STING signaling.
Xin Wang Mo +7 more
wiley +1 more source
Development of novel salicylic acid derivatives with dual anti-inflammatory and anti-arthritic potentials: synthesis, <i>in vitro</i> bio-evaluation, and <i>in silico</i> toxicity prediction with molecular modeling simulations. [PDF]
RSC AdvHesham K, Aboulthana WM, Ragab A.
europepmc +1 more source
Protein Proteinase Inhibitors in Male Sex Glands [PDF]
, 1971 Fink, Edwin +4 more
core +1 more source
4D Mapping of ZIF Biocomposites for High Protein Loading and Tunable Release Profiles
Advanced Functional Materials, EarlyView.Systematic four‐dimensional mapping of zeolitic imidazolate framework biocomposites reveals how precursor ratios, total concentration, and washing define crystalline phase, protein loading, and release kinetics. This comprehensive study identifies conditions yielding record loading (∼85%) and precise phase–property correlations.
Michael R. Hafner +12 more
wiley +1 more source
Impaired Phagocytosis in Peritonitis Exudate Secondary to Complement Consumption [PDF]
, 1988 Billing, A. +3 more
core +1 more source
Synthetic Nanobiology Actuated Lipometabolic Cell Factory for Autologous Tumor Immunotherapy
Advanced Functional Materials, EarlyView.FA plays a crucial role in the interaction between tumor cells and the tumor microenvironment, especially for the immune response. A biocatalytic immunoenhancement strategy is developed to boost antitumor immunity by FA metabolic orientation to ceramide. Through the design of this delicate catalytic immunoenhancement strategy, the synthetic nanobiology
Shoujie Zhao +8 more
wiley +1 more source