Results 101 to 110 of about 10,718,710 (345)
Transferrin Aptamers Increase the In Vivo Blood–Brain Barrier Targeting of Protein Spherical Nucleic Acids [PDF]
, 2022 Caroline D. Kusmierz +4 more
openalex +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Definition of fatty acid transport protein-2 (FATP2) structure facilitates identification of small molecule inhibitors for the treatment of diabetic complications [PDF]
, 2023 Mukesh Kumar +9 more
openalex +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Food Technology and Biotechnology, 2012 Soy yogurts (sogurts) were prepared from germinated soybeans [Glycine max (L.) Merrill] with different hypocotyl lengths. This study is mainly focused on the effects of soybean germination on the rheological characteristics and the microstructure of ...
Mei Yang, Jing Fu, Li Li
doaj
Journal of Translational MedicineSystems biology is a holistic approach to biological sciences that combines experimental and computational strategies, aimed at integrating information from different scales of biological processes to unravel pathophysiological mechanisms and behaviours.
Aurelia Morabito +4 more
doaj +1 more source
Cytoplasmic degradation of ssrA‐tagged proteins [PDF]
, 2005 Christopher M. Farrell +2 more
openalex +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
The Drosophila Peptidoglycan Recognition Protein PGRP-LF Blocks PGRP-LC and IMD/JNK Pathway Activation [PDF]
, 2008 Frédéric Maillet +4 more
openalex +1 more source
Post-translational modulation of cell signalling through protein succinylation [PDF]
, 2023 Katharina F. Kubatzky +2 more
openalex +1 more source