Results 11 to 20 of about 288,185 (387)
Progress in Pathogenesis of Proteinuria [PDF]
International Journal of Nephrology, 2012 Aims. Proteinuria not only is a sign of kidney damage, but also is involved in the progression of renal diseases as an independent pathologic factor. Clinically, glomerular proteinuria is most commonly observed, which relates to structural and functional
Aihua Zhang, Songming Huang
doaj +4 more sources
Pathophysiology of proteinuria [PDF]
Kidney International, 2003 Proteinuria is consequence of two mechanisms: the abnormal transglomerular passage of proteins due to increased permeability of glomerular capillary wall and their subsequent impaired reabsorption by the epithelial cells of the proximal tubuli. In the various glomerular diseases, the severity of disruption of the structural integrity of the glomerular ...
D'Amico, Giuseppe, Bazzi, Claudio
openaire +4 more sources
The epidemiology of chronic kidney disease (CKD) in rural East Africa: A population-based study. [PDF]
, 2020 BackgroundChronic kidney disease (CKD) may be common among individuals living in sub-Saharan Africa due to the confluence of CKD risk factors and genetic predisposition.MethodsWe ascertained the prevalence of CKD and its risk factors among a sample of 3 ...
Atukunda, Mucunguzi +14 more
core +2 more sources
Sex differences in the evaluation of proteinuria using the urine dipstick test
Frontiers in Medicine, 2023 BackgroundThe urine protein dipstick test is widely used, but false-positive and false-negative results may occur. This study aimed to compare the urine protein dipstick test with a urine protein quantification method.MethodsThe data were extracted using
Chiari Kojima +4 more
doaj +1 more source
PLoS ONE, 2022 Diabetic kidney disease (DKD) is heterogeneous in terms of proteinuria. Patients with DKD who present with low-grade proteinuria are more likely to have nephrosclerosis rather than traditional diabetic nephropathy. The amount of proteinuria might reflect
Satoshi Yamaguchi +7 more
doaj +1 more source
Comprehensive genetic diagnosis of Japanese patients with severe proteinuria
Scientific Reports, 2020 Numerous disease-causing gene mutations have been identified in proteinuric diseases, such as nephrotic syndrome and glomerulosclerosis. This report describes the results of comprehensive genetic diagnosis of Japanese patients with severe proteinuria. In
C. Nagano +10 more
semanticscholar +1 more source
Journal of the American Society of Nephrology, 2020 BACKGROUND On the basis of findings of observational studies and a meta-analysis, proteinuria reduction has been proposed as a surrogate outcome in IgA nephropathy. How long a reduction in proteinuria needs to be maintained to mitigate the long-term risk
M. Canney +10 more
semanticscholar +1 more source
Proteinuria Reduction as a Surrogate End Point in Trials of IgA Nephropathy.
American Society of Nephrology. Clinical Journal, 2019 IgA nephropathy (IgAN) is an important cause of ESKD for which there are no approved therapies. A challenge for evaluating treatments for IgAN is the usual long time course for progression to ESKD.
A. Thompson +16 more
semanticscholar +1 more source