Multi‐Scale Analysis of Regional Pathology in the Human Trapezium During Osteoarthritis Progression
ABSTRACT Trapeziometacarpal (TMC) osteoarthritis (OA) is a prevalent condition that significantly impacts hand function and quality of life. In this study we sought to close gaps in knowledge related to the initiation and progression of TMC OA on the tissue scale by evaluating the morphology and gross appearance, wear patterns, mechanical properties ...
Brendan D. Stoeckl+5 more
wiley +1 more source
Low-intensity ultrasound stimulation promotes differentiation of bone marrow mononuclear cells to nucleus pulposus cells for matrix synthesis. [PDF]
Li C, He Y, Chen R, Miao G, Cui J.
europepmc +1 more source
Transcriptome analysis of granulation tissue from periodontal osseous defects
Abstract Background Granulation tissue is routinely discarded in periodontal surgical procedures, but few studies have characterized it. The present study aimed to compare global gene expression in granulation tissue derived from different types of periodontal osseous defects.
Ye Han Sam+5 more
wiley +1 more source
FAM20B Gain-of-Function Blocks the Synthesis of Glycosaminoglycan Chains of Proteoglycans and Inhibits Proliferation and Migration of Glioblastoma Cells. [PDF]
Barré L, Shaukat I, Ouzzine M.
europepmc +1 more source
Incorporation of thiolated chondroitin sulphate in gelAGE hydrogels and the production of heterogeneous samples, allows us to provide cells with a dynamic environment, by tuning hydrogel viscoelasticity, rather than elasticity alone, for functional advancing tissue engineering replacements.
Manuela A. Boos+3 more
wiley +1 more source
Biomimetic Proteoglycans for Intervertebral Disc (IVD) Regeneration. [PDF]
Chopra N, Melrose J, Gu Z, Diwan AD.
europepmc +1 more source
Preclinical Testing of 3D Printed, Cell Loaded Hydrogel Based Corneal Substitutes on Rabbit Model
This study reports on 3D‐printed methacrylated gelatin (GelMA) implants designed to serve as corneal stroma substitutes. The implants are characterized for their transparency, mechanical strength, and cytocompatibility. In vivo tests on rabbits demonstrate successful integration, with histopathological analysis showing tissue regeneration, appropriate ...
Deniz Basoz+6 more
wiley +1 more source
The vertebrate small leucine-rich proteoglycans: amplification of a clustered gene family and evolution of their transcriptional profile in jawed vertebrates. [PDF]
Gil N+3 more
europepmc +1 more source
A new unnatural heteroaminopolysaccahride, that is, α(1→$1{\to} $4)‐linked glucosamino‐2‐deoxyglucan, is successfully synthesized by thermostable glucan phosphorylase (from Aquifex aeolicus VF5)‐catalyzed enzymatic copolymerization of α‐d‐glucosamine 1‐phosphate/‐glucal as comonomers from maltotriose as a primer.
Yuta Miyahara+3 more
wiley +1 more source
A comprehensive analysis of two types of xenogeneic bone particles for use in maxillofacial bone regeneration therapies. [PDF]
Ortiz-Arrabal O+9 more
europepmc +1 more source