Results 211 to 220 of about 80,771 (263)
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Radioimmunoassay of Proteoglycans
Journal of Immunoassay, 1984Human articular cartilage proteoglycan monomers (PG) were purified and used for developing a radioimmunoassay. Its analytical sensitivity is 0.6 ng/tube and its clinical sensitivity is 20 microliter/tube for serum and 0.12 microliter/tube for synovial fluid.
P, Gysen, P, Franchimont
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Proteoglycans and proteoglycan mimetics for tissue engineering
American Journal of Physiology-Cell Physiology, 2022Proteoglycans play a crucial role in proper tissue morphology and function throughout the body that is defined by a combination of their core protein and the attached glycosaminoglycan chains. Although they serve a myriad of roles, the functions of extracellular proteoglycans can be generally sorted into four categories: modulation of tissue ...
Michael Nguyen, Alyssa Panitch
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Progress in Retinal and Eye Research, 2002
In this article, we summarize the roles of proteoglycans in retinal tissue. Chondroitin sulfate and heparan sulfate proteoglycans are the major constituents in proteoglycans expressed in retinal tissue. Soluble heparan sulfate proteoglycans are found in the extracellular matrices of the basement membrane, such as the inner limiting membrane and Bruch's
Masaru, Inatani, Hidenobu, Tanihara
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In this article, we summarize the roles of proteoglycans in retinal tissue. Chondroitin sulfate and heparan sulfate proteoglycans are the major constituents in proteoglycans expressed in retinal tissue. Soluble heparan sulfate proteoglycans are found in the extracellular matrices of the basement membrane, such as the inner limiting membrane and Bruch's
Masaru, Inatani, Hidenobu, Tanihara
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Experientia, 1993
In this review the structure and functions of two non-related proteoglycan families are discussed. One family represents a group of extracellular matrix macromolecules characterized by core proteins with leucine-rich repeat motifs. Within this family special attention is given to those members which carry chondroitin or dermatan sulfate ...
H, Kresse, H, Hausser, E, Schönherr
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In this review the structure and functions of two non-related proteoglycan families are discussed. One family represents a group of extracellular matrix macromolecules characterized by core proteins with leucine-rich repeat motifs. Within this family special attention is given to those members which carry chondroitin or dermatan sulfate ...
H, Kresse, H, Hausser, E, Schönherr
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Proteoglycans in Dentinogenesis
Critical Reviews in Oral Biology & Medicine, 2001The predominant proteoglycans present in predentin and dentin are the chondroitin-sulphate-rich decorin and biglycan and the keratan-sulphate-rich lumican and fibromodulin. These are small, interstitial, leucine-rich proteoglycans which have recently been shown to exist in gradients across the predentin.
G, Embery +4 more
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Proteoglycans in amyloidogenesis
Neurobiology of Aging, 1989The potentially important role of proteoglycans and glycosaminoglycans in the modern concept of general amyloidogenesis has been discussed.
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Cornea, 2002
Various proteoglycans are expressed in ocular tissues. We investigated and reviewed the distribution and the potential roles of proteoglycans in cornea, trabecular meshwork, and retinal tissues.Immunohistochemical studies were performed in rat ocular tissues. The concentration of transforming growth factor (TGF)-beta2, which regulates the expression of
Hidenobu, Tanihara +4 more
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Various proteoglycans are expressed in ocular tissues. We investigated and reviewed the distribution and the potential roles of proteoglycans in cornea, trabecular meshwork, and retinal tissues.Immunohistochemical studies were performed in rat ocular tissues. The concentration of transforming growth factor (TGF)-beta2, which regulates the expression of
Hidenobu, Tanihara +4 more
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Current Pharmaceutical Design, 2017
Most proteoglycans are heterogeneous molecules composed of a protein core with glycosaminoglycans (GAGs) attached. GAGs are highly negatively charged molecules that readily bind to enzymes, growth factors, cytokines etc. and as such have many functions.
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Most proteoglycans are heterogeneous molecules composed of a protein core with glycosaminoglycans (GAGs) attached. GAGs are highly negatively charged molecules that readily bind to enzymes, growth factors, cytokines etc. and as such have many functions.
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1994
Cytokines play an important regulatory role in the metabolism of proteoglycans. Proteoglycans are found in plasma membranes, but predominantly in the extra-cellular matrix. In the latter they are quantitatively and qualitatively essential components. Especially in a tissue like cartilage without any blood vessels, the cells are dependent on cytokines ...
J J, Nietfeld +2 more
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Cytokines play an important regulatory role in the metabolism of proteoglycans. Proteoglycans are found in plasma membranes, but predominantly in the extra-cellular matrix. In the latter they are quantitatively and qualitatively essential components. Especially in a tissue like cartilage without any blood vessels, the cells are dependent on cytokines ...
J J, Nietfeld +2 more
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Bulletin of Experimental Biology and Medicine, 1996
Studies of proteoglycans for their capacity to perform the function of steric exclusion of cells are reviewed. The ability of the proteoglycans hyaluronic acid and protein-chrondroitinkeratosulfate and their aggregates to effect cell aggregation and steric exclusion is determined by the structure of glycosaminoglycan components and the amount of ...
S M, Bychkov, S A, Kuz'mina
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Studies of proteoglycans for their capacity to perform the function of steric exclusion of cells are reviewed. The ability of the proteoglycans hyaluronic acid and protein-chrondroitinkeratosulfate and their aggregates to effect cell aggregation and steric exclusion is determined by the structure of glycosaminoglycan components and the amount of ...
S M, Bychkov, S A, Kuz'mina
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