Biomimetic Hydrogels for In Vitro Modelling of Nucleus Pulposus Degeneration: Effects of Extracellular Matrix Compositional Change on Physicochemical Properties and Cell Phenotype. [PDF]
Rashidi N +4 more
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Linking Elastin in Skeletal Muscle Extracellular Matrix to Metabolic and Aerobic Function in Type 2 Diabetes: A Secondary Analysis of a Lower Leg Training Intervention. [PDF]
Hulett NA +5 more
europepmc +1 more source
Matrisome remodeling in the myocardium of hypertrophic cardiomyopathy; novel targets for molecular diagnostics. [PDF]
Ibrahim AM +3 more
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Heparin Provides Antiviral Activity Against Rhinovirus-16 via an Heparan Sulfate Proteoglycan-Independent Mechanism. [PDF]
Helgers LC +5 more
europepmc +1 more source
The Influence of Sirtuin 6 on Chondrocyte Senescence in Osteoarthritis Under Aging: Focusing on Mitochondrial Dysfunction and Oxidative Stress. [PDF]
Zhao H, Wu W.
europepmc +1 more source
Fourier Transform Infrared Spectroscopic Characterization of Aortic Wall Remodeling by Stable Gastric Pentadecapeptide BPC 157 After Unilateral Adrenalectomy in Rats. [PDF]
Smoday IM +21 more
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Proteoglycans and proteoglycan mimetics for tissue engineering
American Journal of Physiology-Cell Physiology, 2022Proteoglycans play a crucial role in proper tissue morphology and function throughout the body that is defined by a combination of their core protein and the attached glycosaminoglycan chains. Although they serve a myriad of roles, the functions of extracellular proteoglycans can be generally sorted into four categories: modulation of tissue ...
Michael Nguyen, Alyssa Panitch
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In this review the structure and functions of two non-related proteoglycan families are discussed. One family represents a group of extracellular matrix macromolecules characterized by core proteins with leucine-rich repeat motifs. Within this family special attention is given to those members which carry chondroitin or dermatan sulfate ...
H, Kresse, H, Hausser, E, Schönherr
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The structure, biosynthesis, localization, and possible functional roles of nervous tissue glycosaminoglycans and proteoglycans were last reviewed several years ago. Since that time, there has been an exponential increase in publications on the neurobiology of proteoglycans.
R U, Margolis, R K, Margolis
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