Results 341 to 350 of about 189,785 (400)
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Functions of cell surface heparan sulfate proteoglycans.
Annual Review of Biochemistry, 1999The heparan sulfate on the surface of all adherent cells modulates the actions of a large number of extracellular ligands. Members of both cell surface heparan sulfate proteoglycan families, the transmembrane syndecans and the glycosylphosphoinositide ...
M. Bernfield +6 more
semanticscholar +1 more source
Experientia, 1993
In this review the structure and functions of two non-related proteoglycan families are discussed. One family represents a group of extracellular matrix macromolecules characterized by core proteins with leucine-rich repeat motifs. Within this family special attention is given to those members which carry chondroitin or dermatan sulfate ...
Elke Schönherr +2 more
openaire +4 more sources
In this review the structure and functions of two non-related proteoglycan families are discussed. One family represents a group of extracellular matrix macromolecules characterized by core proteins with leucine-rich repeat motifs. Within this family special attention is given to those members which carry chondroitin or dermatan sulfate ...
Elke Schönherr +2 more
openaire +4 more sources
Proteoglycans: structures and interactions.
Annual Review of Biochemistry, 1991n, sulfation, L-iduronic acid, glycosam inoglycan-protei n in teractions, extracellular matrix.
L. Kjellén, U. Lindahl
semanticscholar +1 more source
Progress in Retinal and Eye Research, 2002
In this article, we summarize the roles of proteoglycans in retinal tissue. Chondroitin sulfate and heparan sulfate proteoglycans are the major constituents in proteoglycans expressed in retinal tissue. Soluble heparan sulfate proteoglycans are found in the extracellular matrices of the basement membrane, such as the inner limiting membrane and Bruch's
Hidenobu Tanihara, Masaru Inatani
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In this article, we summarize the roles of proteoglycans in retinal tissue. Chondroitin sulfate and heparan sulfate proteoglycans are the major constituents in proteoglycans expressed in retinal tissue. Soluble heparan sulfate proteoglycans are found in the extracellular matrices of the basement membrane, such as the inner limiting membrane and Bruch's
Hidenobu Tanihara, Masaru Inatani
openaire +2 more sources
Cornea, 2002
Various proteoglycans are expressed in ocular tissues. We investigated and reviewed the distribution and the potential roles of proteoglycans in cornea, trabecular meshwork, and retinal tissues.Immunohistochemical studies were performed in rat ocular tissues. The concentration of transforming growth factor (TGF)-beta2, which regulates the expression of
Hidenobu Tanihara +4 more
openaire +2 more sources
Various proteoglycans are expressed in ocular tissues. We investigated and reviewed the distribution and the potential roles of proteoglycans in cornea, trabecular meshwork, and retinal tissues.Immunohistochemical studies were performed in rat ocular tissues. The concentration of transforming growth factor (TGF)-beta2, which regulates the expression of
Hidenobu Tanihara +4 more
openaire +2 more sources
Biomacromolecules, 2017
Aging and degeneration of human tissue come with the loss of tissue water retention and associated changes in physical properties partially due to degradation and subsequent loss of proteoglycans.
K. Prudnikova +6 more
semanticscholar +1 more source
Aging and degeneration of human tissue come with the loss of tissue water retention and associated changes in physical properties partially due to degradation and subsequent loss of proteoglycans.
K. Prudnikova +6 more
semanticscholar +1 more source
Proteoglycans in Dentinogenesis
Critical Reviews in Oral Biology & Medicine, 2001The predominant proteoglycans present in predentin and dentin are the chondroitin-sulphate-rich decorin and biglycan and the keratan-sulphate-rich lumican and fibromodulin. These are small, interstitial, leucine-rich proteoglycans which have recently been shown to exist in gradients across the predentin.
Graham Embery +4 more
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Proteoglycans in amyloidogenesis
Neurobiology of Aging, 1989The potentially important role of proteoglycans and glycosaminoglycans in the modern concept of general amyloidogenesis has been discussed.
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Evidence of proteoglycan/proteoglycan interactions within aggregates
Journal of Orthopaedic Research, 1991AbstractNonaggregated proteoglycan monomers, digested fragments of the monomers, as well as link proteins have been shown to self‐associate. These associations have not been shown to occur on the aggregate. However, previous reports, using the Kleinschmidt technique of monolayer electron microscopy, have noted proteoglycan subunits on the aggregate ...
Randall W. Viola +3 more
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Current Pharmaceutical Design, 2017
Most proteoglycans are heterogeneous molecules composed of a protein core with glycosaminoglycans (GAGs) attached. GAGs are highly negatively charged molecules that readily bind to enzymes, growth factors, cytokines etc. and as such have many functions.
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Most proteoglycans are heterogeneous molecules composed of a protein core with glycosaminoglycans (GAGs) attached. GAGs are highly negatively charged molecules that readily bind to enzymes, growth factors, cytokines etc. and as such have many functions.
openaire +2 more sources