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A History of Proteolipids: A Personal Memoir
Neurochemical Research, 1998This review is a personal memoir of the history of proteolipids and is limited to aspects of the field with which the author has been involved in one way or another. The discovery of proteolipids was a serendipitous observation made in the course of the study of sulfatides. Initial focus was on the chemical characterization of brain proteolipids, their
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The Rh antigen specificity of erythrocyte proteolipid
Transfusion, 1984A proteolipid was purified from erythrocytes by chloroform‐methanol extraction and reconstituted into lipid micelles. This purified micellar proteolipid was used to demonstrate that different Rh antigens reside on the same protein molecule.
L T, Sinor +3 more
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Proteolipid and bovine aorta calcification, in vitro
Atherosclerosis, 1983Proteolipid was examined for nucleation of bovine aorta calcification. Tissue homogenates were tested for in vitro calcifiability before and after lipid extraction followed by similar tests of the extract and its fractions. The tissue calcified before but not after lipid extraction. Of the lipid fractions, only proteolipid calcified.
J, Ennever, L J, Riggan
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Proteolipidic Vectors for Gene Transfer to the Lung
Biochemical and Biophysical Research Communications, 2002In order to develop improved synthetic gene transfer vectors, we have synthesized bifunctional peptides composed of a DNA binding peptide (P2) and ligand peptides selected by the phage display technique on tracheal epithelial cells. We have evaluated the capacity of these peptides to enhance the gene transfer efficiency of the cationic lipid DOTAP to ...
Vaysse, Laurence +5 more
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Proteolipid as a binding site for 2-haloalkylamines
Biochemical Pharmacology, 1971Abstract Vasa of guinea-pigs were incubated with a 2-halogenoalkylamine [ 14 C]Sy28 30 μM, 25 mc/m-mole, before or during exposure to 3.65 mM phentolamine, extracted with 2:1 chloroform-methanol and the extracts washed. The organic (lower) phase was subjected to hydrolysis with 6 N HCl and autoradiographs of paper chromatographs made. Three spots (in
D R, Mottram, J D, Graham
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Molecular Evolution of Myelin Proteolipid Protein
Biochemical and Biophysical Research Communications, 1997We show that the major membrane protein of central nervous system myelin, proteolipid protein, evolved much more rapidly than it does now more than 300 million years ago. We reason that myelin proteolipid protein evolved rapidly just after its appearance in vertebrates and that its evolutionary rate then gradually decreased.
T, Kurihara, M, Sakuma, T, Gojobori
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Redefining the lipophilin family of proteolipid proteins
Journal of Neuroscience Research, 1997The past few years have seen a dramatic increase in our understanding, in molecular terms, of the involvement of the central nervous system proteolipid protein in myelinogenesis and X-linked genetic diseases. In addition, we have expanded our knowledge of the proteins that have been recruited into the vertebrate myelin membrane over the past 400 ...
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Isoelectric focusing of proteolipid
Journal of Neurochemistry, 1978M, Draper, M B, Lees, D S, Chan
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Biochimica et Biophysica Acta (BBA) - Specialized Section on Lipids and Related Subjects, 1964
M.L. Das, D.E. Myers, F.L. Crane
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M.L. Das, D.E. Myers, F.L. Crane
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