Results 141 to 150 of about 538,471 (385)

Author response: A high-throughput yeast display approach to profile pathogen proteomes for MHC-II binding

, 2022
Brooke D. Huisman, Zheng Dai, David K. Gifford, Michael E. Birnbaum   +3 more
openalex   +1 more source

A time-resolved multi-omic atlas of the developing mouse stomach

Nature Communications, 2018
The mammalian stomach is a complex organ with diverse roles in health and disease. Here, the authors integrate proteomics and transcriptomics to analyze the mouse stomach at 15 time points during development, providing molecular level insights into ...
Xianju Li, Chunchao Zhang, Tongqing Gong, Xiaotian Ni, Jin’e Li, Dongdong Zhan, Mingwei Liu, Lei Song, Chen Ding, Jianming Xu, Bei Zhen, Yi Wang, Jun Qin   +12 more
doaj   +1 more source

Networks of motifs from sequences of symbols

, 2010
We introduce a method to convert an ensemble of sequences of symbols into a weighted directed network whose nodes are motifs, while the directed links and their weights are defined from statistically significant co-occurences of two motifs in the same ...
Condorelli, Daniele, Latora, Vito, Sinatra, Roberta   +2 more
core   +1 more source

Nano‐Engineered Titanium Implants Loaded With Gingival Fibroblasts‐Derived Microvesicles Enhance Early Osseointegration And Soft Tissue Attachment In Vivo

Advanced Healthcare Materials, EarlyView.
Our study showed that human primary gingival fibroblast–derived microvesicles on nano‐engineered titanium implants promote early osseointegration and soft‐tissue attachment in vivo. ABSTRACT Titanium dental implants require both reliable osseointegration and peri‐implant soft tissue seal formation to ensure long‐term success. While osseointegration has
Pingping Han, Chun Liu, Anjana Jayasree, Kamil Sokolowski, Andrew Liaw, Dingbin Liu, Carlos Salomon, Karan Gulati, Ryan SB Lee, Baoxin Huang, Sašo Ivanovski   +10 more
wiley   +1 more source

Impact of OqxR loss of function on the envelope proteome of Klebsiella pneumoniae and susceptibility to antimicrobials [PDF]

, 2018
Wan Ahmad Kamil Wan Nur Ismah, Yuiko Takebayashi, Jacqueline Findlay, Kate J. Heesom, Matthew B. Avison   +4 more
openalex   +1 more source

A protein sequence-based deep transfer learning framework for identifying human proteome-wide deubiquitinase-substrate interactions

Nature Communications
Protein ubiquitination regulates a wide range of cellular processes. The degree of protein ubiquitination is determined by the delicate balance between ubiquitin ligase (E3)-mediated ubiquitination and deubiquitinase (DUB)-mediated deubiquitination.
Yuan Liu, Dianke Li, Xin Zhang, Simin Xia, Yingjie Qu, Xinping Ling, Yang Li, Xiangren Kong, Lingqiang Zhang, Chun-Ping Cui, Dong Li   +10 more
doaj   +1 more source

Isolation Defines Identity: Functional Consequences of Extracellular Vesicle Purification Strategies

Advanced Healthcare Materials, EarlyView.
Four extracellular vesicle purification strategies are compared using ovarian‐cancer ascites and ES‐2 cell supernatants. A novel workflow links purification to function by combining particle‐normalized proteomics with matched cell‐free and cell‐based assays.
Christian Preußer, Dolores J. Salander, Witold Szymanski, Johannes Graumann, Yukai Wang, Kai Zhao, Jörg W. Bartsch, María Gómez‐Serrano, Daniel Bachurski, Silke Reinartz, Elke von Pogge von Strandmann   +10 more
wiley   +1 more source

Nuclear and cytoplasmic specific RNA binding proteome enrichment and its changes upon ferroptosis induction

Nature Communications
The key role of RNA-binding proteins (RBPs) in posttranscriptional regulation of gene expression is intimately tied to their subcellular localization. Here, we show a subcellular-specific RNA labeling method for efficient enrichment and deep profiling of
Haofan Sun, Bin Fu, Xiaohong Qian, Ping Xu, Weijie Qin   +4 more
doaj   +1 more source

A Quantitative Proteome Map of the Human Body

Cell, 2019
Determining protein levels in each tissue and how they compare with RNA levels is important for understanding human biology and disease as well as regulatory processes that control protein levels.
Lihua Jiang, Meng Wang, Shin Lin, Ruiqi Jian, Xiao Li, Joanne Chan, Guanlan Dong, Huaying Fang, Aaron E. Robinson, Michael P. Snyder, F. Aguet, Shankara K. Anand, K. Ardlie, S. Gabriel, G. Getz, Aaron P. Graubert, Kane Hadley, R. Handsaker, Katherine H. Huang, Seva Kashin, D. MacArthur, Samuel R. Meier, Jared L. Nedzel, Duyen Y. Nguyen, A. Segrè, E. Todres, Brunilda Balliu, A. Barbeira, A. Battle, Rodrigo Bonazzola, A. Brown, Christopher D. Brown, Stephane E. Castel, Don Conrad, D. Cotter, N. Cox, Sayantani Das, Olivia M. de Goede, E. Dermitzakis, B. Engelhardt, E. Eskin, Tiffany Y. Eulalio, N. Ferraro, Elise D. Flynn, L. Frésard, E. Gamazon, D. Garrido-Martín, Nicole R. Gay, R. Guigó, Andrew R. Hamel, Yuan He, Paul J. Hoffman, F. Hormozdiari, L. Hou, H. Im, Brian Jo, S. Kasela, Manolis Kellis, Sarah Kim-Hellmuth, Alan M. Kwong, T. Lappalainen, Xin Li, Yanyu Liang, S. Mangul, P. Mohammadi, S. Montgomery, Manuel Muñoz-Aguirre, Daniel C. Nachun, A. Nobel, Meritxell Oliva, YoSon Park, Yongjin P. Park, P. Parsana, F. Reverter, J. Rouhana, C. Sabatti, A. Saha, Andrew Skol, M. Stephens, B. Stranger, B. Strober, Nicole A. Teran, A. Viñuela, Gao Wang, Xiaoquan Wen, Fred A. Wright, Valentin Wucher, Yuxin Zou, Pedro G. Ferreira, Gen Li, Marta Melé, Esti Yeger-Lotem, M. Barcus, Debra Bradbury, Tanya Krubit, J. McLean, L. Qi, Karna L. Robinson, Nancy V. Roche, Anna M. Smith, L. Sobin, D. Tabor, Anita H. Undale, J. Bridge, L. Brigham, B. Foster, Bryan M. Gillard, R. Hasz, Marcus Hunter, Christopher Johns, Mark Johnson, E. Karasik, G. Kopen, W. F. Leinweber, Alisa McDonald, M. T. Moser, K. Myer, Kimberley D. Ramsey, Brian Roe, Saboor Shad, Jeffrey A. Thomas, Gary Walters, Michael Washington, Joseph Wheeler, S. Jewell, D. Rohrer, Dana R. Valley, D. Davis, D. Mash, P. Branton, Laura K. Barker, H. Gardiner, M. Mosavel, L. Siminoff, P. Flicek, M. Haeussler, Thomas Juettemann, W. Kent, Christopher M. Lee, Conner C. Powell, K. Rosenbloom, Magali Ruffier, Daniel Sheppard, K. Taylor, S. Trevanion, D. Zerbino, Nathan S. Abell, J. Akey, Lin Chen, Kathryn Demanelis, J. Doherty, A. Feinberg, K. Hansen, P. Hickey, F. Jasmine, R. Kaul, M. Kibriya, Jin Li, Qin Li, Sandra Linder, B. Pierce, L. Rizzardi, Kevin S. Smith, J. Stamatoyannopoulos, Hua Tang, Latarsha J. Carithers, P. Guan, S. Koester, A. Little, Helen M. Moore, C. Nierras, Abhi Rao, J. Vaught, S. Volpi   +173 more
semanticscholar   +1 more source

Serotonergic System‐Targeted Nucleic Acid Hydrogel Coordinates Excitability Restoration and Circuit Reconstruction for Spinal Cord Injury Therapy

Advanced Materials, EarlyView.
The study reports a DNA/RNA heteroduplex hydrogel (SeroPTEN‐CG) that undergoes DNase‐mediated hydrogel‐to‐nanogel transition for spinal cord injury therapy by targeting the serotonergic system, combining 5‐hydroxytryptamine (5‐HT)‐mediated excitability restoration to reactivate dormant interneurons with phosphatase and tensin homolog (PTEN)‐targeted ...
Chunlin Li, Xiaoqing Zhao, Kai Jiang, Haixia Kang, Shuo Liu, Linlin Jiang, Baoshuai Bai, Haonan Cui, Ziyang Zhang, Menglei Dong, Ruizhi Zhang, Chenbo Zou, Shenghui Shang, Chi Zhang, Xiangchuang Fan, Lijuan Zhu, Huiquan Duan, Chuan Zhang, Shiqing Feng, Hengxing Zhou   +19 more
wiley   +1 more source