Results 81 to 90 of about 299,370 (300)

Proteome-Wide Evaluation of Two Common Protein Quantification Methods

, 2018
Proteomics experiments commonly aim to estimate and detect differential abundance across all expressed proteins. Within this experimental design, some of the most challenging measurements are small fold changes for lower abundance proteins.
Steven P. Gygi (90226), Joao A. Paulo (397190), Jonathon J. O’Brien (4687588), Jeremy D. O’Connell (5121230)   +3 more
core   +3 more sources

The Green Proteome: Challenges in Plant Proteomics [PDF]

Frontiers in Plant Science, 2011
An organism is an expression of its underlying molecular composition that reacts and responds to a variety of stimuli. Central to this response are proteins, which undertake a multitude of functional and structural roles throughout an organism.
openaire   +3 more sources

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

The Transcriptional Regulator Crt1 is Involved in The Pathogenic Lifestyle of Xanthomonas campestris pv. campestris B100

Polish Journal of Microbiology
The γ-proteobacterium Xanthomonas campestris pv. campestris B100 is the causal agent of black rot disease in a wide range of economically important crops. In addition, X. campestris pv.
Korszańska Anna, Lutter Petra, Ortseifen Vera, Pühler Alfred, Niehaus Karsten   +4 more
doaj   +1 more source

Progress Identifying and Analyzing the Human Proteome: 2021 Metrics from the HUPO Human Proteome Project

, 2021
The 2021 Metrics of the HUPO Human Proteome Project (HPP) show that protein expression has now been credibly detected (neXtProt PE1 level) for 18,357 (92.8%) of the 19,778 predicted proteins coded in the human genome, a gain of 483 since 2020 from ...
Chen, Yu-Ju, Moritz, Robert L., Weintraub, Susan,, Aebersold, Ruedi,, Srivastava, Sudhir,, Omenn, Gilbert S.,, Bandeira, Nuno,, Cristea, Ileana M., Roehrl, Michael H.A., Overall, Christopher M.,, Liu, Siqi,, Paik, Young-Ki, Weintraub, Susan, Bandeira, Nuno, Deutsch, Eric W., Omenn, Gilbert S., Deutsch, Eric W.,, Corrales, Fernando J., Cristea, Ileana M.,, Roehrl, Michael H. A.,, Chen, Yu-Ju,, Liu, Siqi, Corrales, Fernando J.,, Srivastava, Sudhir, Moritz, Robert L, Deutsch, Eric W, Omenn, Gilbert S, Lindskog, Cecilia, Paik, Young-Ki,, Cristea, Ileana M, Corrales, Fernando J, Aebersold, Ruedi, Overall, Christopher M., Lindskog, Cecilia,, Roehrl, Michael H A, Lane, Lydie,, Overall, Christopher M, Lane, Lydie, Moritz, Robert L.,, Yu-Ju Chen, Lydie Lane, Nuno Bandeira, Robert L. Moritz, Fernando J. Corrales, Ileana M. Cristea, Eric W. Deutsch, Ruedi Aebersold, Susan Weintraub, Young-Ki Paik, Cecilia Lindskog, Sudhir Srivastava, Gilbert S. Omenn, Michael H. A. Roehrl, Siqi Liu, Christopher M. Overall   +54 more
core   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

Heat stabilization of the tissue proteome : a new technology for improved proteomics

, 2009
After tissue or body fluid sampling, proteases and other protein-modifying enzymes can rapidly change composition of the proteome. As a direct consequence, analytical results will reflect a mix of in vivo proteome and ex vivo degradation products.
Andrén, Per E.,, Sjogren, Benita, Svensson, Marcus, Andersson, Malin,, Fälth, Maria,, Svenningsson, Per, Boren, Mats, Skold, Karl   +7 more
core   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

Identification and characterization of a gene conferring stress resistance in Escherichia coli and cyanobacteria

FEBS Open Bio, EarlyView.
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada, Takaaki Tanaka, Manaka Uehara, Keigo Nakano, Ken Morishima, Rintaro Inoue, Masaaki Sugiyama, Masafumi Yohda   +7 more
wiley   +1 more source

Proteomic maps of synapses and synaptic vesicles across the central and enteric nervous systems

Communications Biology
While the synaptic proteome of the central nervous system (CNS) has been extensively characterized, its composition in the peripheral nervous system (PNS) remains unknown.
Shiqi Liu, Qiwang Huang, Zhiwei Tu, Hao Shen, Guibin Wang, Huanjiao Jing, Yaoyao Bian, Xulian Cui, Linshuai Cui, Jian Wang, Chenxi Jia   +10 more
doaj   +1 more source