Results 81 to 90 of about 267,519 (299)

The Green Proteome: Challenges in Plant Proteomics [PDF]

Frontiers in Plant Science, 2011
An organism is an expression of its underlying molecular composition that reacts and responds to a variety of stimuli. Central to this response are proteins, which undertake a multitude of functional and structural roles throughout an organism.
openaire   +3 more sources

Corrigendum to “Oxidized/deamidated-ceruloplasmin dysregulates choroid plexus epithelial cells functionality and barrier properties via RGD-recognizing integrin binding” [Neurobiology of Disease 158 (October 2021) DOI: 10.1016/j.nbd.2021.105474]

Neurobiology of Disease, 2022
A. Zanardi, M. Barbariga, A. Conti, F. Vegliani, F. Curnis, M. Alessio   +5 more
doaj   +1 more source

Proteomic analysis of DEN and CCl4-induced hepatocellular carcinoma mouse model

Scientific Reports
Hepatocellular carcinoma (HCC) seriously threatens human health, mostly developed from liver fibrosis or cirrhosis. Since diethylnitrosamine (DEN) and carbon tetrachloride (CCl4)-induced HCC mouse model almost recapitulates the characteristic of HCC with
Qian Zhang, Yuhui Liu, Liangliang Ren, Junqing Li, Weiran Lin, Lijuan Lou, Minghan Wang, Chaoying Li, Ying Jiang   +8 more
doaj   +1 more source

A selective c-Met and Trks inhibitor Indo5 suppresses hepatocellular carcinoma growth

Journal of Experimental & Clinical Cancer Research, 2019
Background Human hepatocellular carcinoma (HCC) lacks effective curative therapy and there is an urgent need to develop a novel molecular-targeted therapy for HCC. Selective tyrosine kinase inhibitors have shown promise in treating cancers including HCC.
Teng Luo, Shou-Guo Zhang, Ling-Fei Zhu, Fei-Xiang Zhang, Wei Li, Ke Zhao, Xiao-Xue Wen, Miao Yu, Yi-Qun Zhan, Hui Chen, Chang-Hui Ge, Hui-Ying Gao, Lin Wang, Xiao-Ming Yang, Chang-Yan Li   +14 more
doaj   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Heat stabilization of the tissue proteome : a new technology for improved proteomics

, 2009
After tissue or body fluid sampling, proteases and other protein-modifying enzymes can rapidly change composition of the proteome. As a direct consequence, analytical results will reflect a mix of in vivo proteome and ex vivo degradation products.
Andrén, Per E.,, Sjogren, Benita, Svensson, Marcus, Andersson, Malin,, Fälth, Maria,, Svenningsson, Per, Boren, Mats, Skold, Karl   +7 more
core   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Absolute quantification of microvesicular proteome elucidating the origin specific signature

, 2010
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core  

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

The proteome of the heterocyst cell wall in Anabaena sp. PCC 7120 [PDF]

, 2007
Anabaena sp. PCC 7120 is a filamentous cyanobacterium that serves as a model to analyze prokaryotic cell differentiation, evolutionary development of plastids, and the regulation of nitrogen fixation.
Flores, Enrique, Vosyka, Oliver, Plöscher, Matthias, Schleiff, Enrico, Mirus, Oliver, Moslavac, Suncana, Reisinger, Veronika, Berg, Matthias, Eichacker, Lutz A.   +8 more
core   +1 more source