Results 21 to 30 of about 491,374 (284)

Joint single-cell DNA accessibility and protein epitope profiling reveals environmental regulation of epigenomic heterogeneity. [PDF]

, 2018
Here we introduce Protein-indexed Assay of Transposase Accessible Chromatin with sequencing (Pi-ATAC) that combines single-cell chromatin and proteomic profiling. In conjunction with DNA transposition, the levels of multiple cell surface or intracellular
Chang, Howard Y, Chen, Xingqi, Choudhry, Hani, Giaccia, Amato J, Greenleaf, William J, LaGory, Edward L, Litzenburger, Ulrike M, Schep, Alicia N, Wei, Yuning   +8 more
core   +2 more sources

Data on genome analysis of Mycoplasma gallisepticum during intracellular infection

Data in Brief, 2017
The genus Mycoplasma relates to Gram-positive bacteria that lack a cell wall and are capable to cause chronic disease in humans and animals. Among the agents of infection and disease in domestic poultry and wild birds, Mycoplasma gallisepticum is the ...
Daria Matyushkina, Olga Pobeguts, Irina Garanina, Vladislav Babenko, Maria Vakhitova, Gleb Fisunov, Vadim Govorun   +6 more
doaj   +1 more source

Differential Proteomic Expression of Equine Cardiac and Lamellar Tissue During Insulin-Induced Laminitis

Frontiers in Veterinary Science, 2020
Endocrinopathic laminitis is pathologically similar to the multi-organ dysfunction and peripheral neuropathy found in human patients with metabolic syndrome.
Allison Campolo, Matthew W. Frantz, Melody A. de Laat, Melody A. de Laat, Steven D. Hartson, Martin O. Furr, Véronique A. Lacombe   +6 more
doaj   +1 more source

Proteomics for prediction of disease progression and response to therapy in diabetic kidney disease [PDF]

, 2016
The past decade has resulted in multiple new findings of potential proteomic biomarkers of diabetic kidney disease (DKD). Many of these biomarkers reflect an important role in the (patho)physiology and biological processes of DKD.
Heerspink, Hiddo J.L., Mischak, Harald, Pena, Michelle J.   +2 more
core   +2 more sources

The Effect of Neurotoxin MPTP and Neuroprotector Isatin on the Profile of Ubiquitinated Brain Mitochondrial Proteins

Cells, 2018
Mitochondria are a crucial target for the actions of neurotoxins, causing symptoms of Parkinson’s disease in various experimental animal models, and also neuroprotectors.
Olga Buneeva, Arthur Kopylov, Inga Kapitsa, Elena Ivanova, Victor Zgoda, Alexei Medvedev   +5 more
doaj   +1 more source

Profiling plasma‐extracellular vesicle proteins and microRNAs in diabetes onset in middle‐aged male participants in the ELSA‐Brasil study

Physiological Reports, 2021
We measured plasma‐derived extracellular vesicle (EV) proteins and their microRNA (miRNA) cargos in normoglycemic (NG), glucose intolerant (GI), and newly diagnosed diabetes mellitus (DM) in middle‐aged male participants of the Brazilian Longitudinal ...
Laureane N. Masi, Paulo A. Lotufo, Frederico M. Ferreira, Alice C. Rodrigues, Tamires D. A. Serdan, Talita Souza‐Siqueira, Aécio A. Braga, Magda E. G. Saldarriaga, Tatiana C. Alba‐Loureiro, Fernanda T. Borges, Diego P. Cury, Mario H. Hirata, Renata Gorjão, Tania C. Pithon‐Curi, Simão A. Lottenberg, Ligia M. G. Fedeli, Helder T. I. Nakaya, Isabela J. M. Bensenor, Rui Curi, Sandro M. Hirabara   +19 more
doaj   +1 more source

Allogeneic Antigen Composition for Preparing Universal Cancer Vaccines

Journal of Immunology Research, 2016
Recently it was demonstrated that tumors induce specific changes to the surface of human endothelial cells thereby providing the basis for designing endothelial cell-based vaccines that directly target antigens expressed by the tumor endothelium.
Petr G. Lokhov, Elena E. Balashova
doaj   +1 more source

Multiple short windows of calcium-dependent protein kinase 4 activity coordinate distinct cell cycle events during Plasmodium gametogenesis

eLife, 2017
Malaria transmission relies on the production of gametes following ingestion by a mosquito. Here, we show that Ca2+-dependent protein kinase 4 controls three processes essential to progress from a single haploid microgametocyte to the release of eight ...
Hanwei Fang, Natacha Klages, Bastien Baechler, Evelyn Hillner, Lu Yu, Mercedes Pardo, Jyoti Choudhary, Mathieu Brochet   +7 more
doaj   +1 more source

Proteomic and metabolomic analysis of Nicotiana benthamiana under dark stress

FEBS Open Bio, 2022
Exposure to extended periods of darkness is a common source of abiotic stress that significantly affects plant growth and development. To understand how Nicotiana benthamiana responds to dark stress, the proteomes and metabolomes of leaves treated with ...
Juan‐Juan Shen, Qian‐Si Chen, Ze‐Feng Li, Qing‐Xia Zheng, Ya‐Long Xu, Hui‐Na Zhou, Hong‐Yan Mao, Qi Shen, Ping‐Ping Liu   +8 more
doaj   +1 more source

How shall we use the proteomics toolbox for biomarker discovery? [PDF]

, 2007
Biomarker discovery for clinical purposes is one of the major areas in which proteomics is used. However, despite considerable effort, the successes have been relatively scarce.
Hochstrasser, Denis, Lescuyer, Pierre, Rabilloud, Thierry   +2 more
core   +5 more sources