Results 31 to 40 of about 491,374 (284)
A proteomic atlas of senescence-associated secretomes for aging biomarker development. [PDF]
, 2020 The senescence-associated secretory phenotype (SASP) has recently emerged as a driver of and promising therapeutic target for multiple age-related conditions, ranging from neurodegeneration to cancer.
Basisty, Nathan +11 more
core +1 more source
The Role of the Nuclear Receptor FXR in Arsenic-Induced Glucose Intolerance in Mice
Toxics, 2023 Inorganic arsenic in drinking water is prioritized as a top environmental contaminant by the World Health Organization, with over 230 million people potentially being exposed. Arsenic toxicity has been well documented and is associated with a plethora of
Yifei Yang +3 more
doaj +1 more source
Data in Brief, 2016 This data article describes a controlled, spiked proteomic dataset for which the “ground truth” of variant proteins is known. It is based on the LC-MS analysis of samples composed of a fixed background of yeast lysate and different spiked amounts of the ...
Claire Ramus +17 more
doaj +1 more source
Frontiers in Cardiovascular Medicine, 2021 Multiple myeloma (MM) is the second most frequent hematologic cancer in the United States. Carfilzomib (CFZ), an irreversible proteasome inhibitor being used to treat relapsed and refractory MM, has been associated with cardiotoxicity, including heart ...
Marwa Tantawy +19 more
doaj +1 more source
Proteomic Changes Associated With Sperm Fertilizing Ability in Meat-Type Roosters
Frontiers in Cell and Developmental Biology, 2021 The molecular basis of male fertility remains unclear, especially in chickens, where decades of genetic selection increased male fertility variability as a side effect.
Anaïs Vitorino Carvalho +13 more
doaj +1 more source
Omics analysis in nutrition science
Mexican Journal of Medical Research ICSA, 2022 The prevalence of diseases affecting human health related to the environment and inadequate nutrition is high. Strategies that seek to mitigate them have focused on lifestyle changes and healthy nutrition focusing on general guidelines that do not ...
Wendoline Anaya Morua
doaj +1 more source
Addressing the needs of traumatic brain injury with clinical proteomics. [PDF]
, 2014 BackgroundNeurotrauma or injuries to the central nervous system (CNS) are a serious public health problem worldwide. Approximately 75% of all traumatic brain injuries (TBIs) are concussions or other mild TBI (mTBI) forms.
Loo, Joseph A +3 more
core +1 more source
Journal of Thrombosis and Haemostasis, 2003 As anucleate cell particles, platelets do not lend themselves to analysis by traditional cell and molecular biology techniques. Moreover, while valuable information may be gleaned from studies of messenger RNA in platelets, the rapid events in platelets are not governed by or dependent on alterations in gene expression.
P B, Maguire, D J, Fitzgerald
openaire +2 more sources
BMC Bioinformatics, 2019 Background Currently, formal mechanisms for bioinformatics support are limited. The H3Africa Bioinformatics Network has implemented a public and freely available Helpdesk (HD), which provides generic bioinformatics support to researchers through an ...
Judit Kumuthini +11 more
doaj +1 more source
The evolutionary rewiring of ubiquitination targets has reprogrammed the regulation of carbon assimilation in the pathogenic yeast Candida albicans [PDF]
, 2012 Date of Acceptance: 13/11/2012 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-ShareAlike 3.0 Unported license, which permits unrestricted noncommercial use, distribution, and reproduction in ...
Ashe +78 more
core +1 more source