Results 261 to 270 of about 22,304,287 (299)

Proteomics Analysis of the Alzheimer's Disease Hippocampal Proteome

Journal of Alzheimer's Disease, 2007
Alzheimer's disease (AD) is characterized by the presence of intracellular neurofibrillary tangles (NFT), extracellular senile plaques (SP), and synaptic loss. The hippocampus is a region that plays an important role in memory and cognitive function, and it is severely affected in AD.
Rukhsana, Sultana, Debra, Boyd-Kimball, Jain, Cai, William M, Pierce, Jon B, Klein, Michael, Merchant, D Allan, Butterfield   +6 more
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Analysis of the plant proteome

Current Opinion in Biotechnology, 2001
For many years the analysis of plant proteomes has been restricted to the construction of descriptive catalogues or the search for markers. The analysis of plant proteomes is now gaining a functional dimension, however, because the focus has shifted onto well-defined plant-specific tissues and organelles, the simultaneous mining of proteomic and ...
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Advances in shotgun proteomics and the analysis of membrane proteomes

Journal of Proteomics, 2010
The emergence of shotgun proteomics has facilitated the numerous biological discoveries made by proteomic studies. However, comprehensive proteomic analysis remains challenging and shotgun proteomics is a continually changing field. This review details the recent developments in shotgun proteomics and describes emerging technologies that will influence
Joshua M, Gilmore, Michael P, Washburn
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Proteome analysis ofCorynebacterium glutamicum

ELECTROPHORESIS, 2001
By the use of different Corynebacterium glutamicum strains more than 1.4 million tons of amino acids, mainly L-glutamate and L-lysine, are produced per year. A project was started recently to elucidate the complete DNA sequence of this bacterium. In this communication we describe an approach to analyze the C.
Hermann, T., Pfefferle, W., Baumann, C., Busker, E., Schaffer, S., Bott, M., Sahm, H., Dusch, N., Kalinowski, Jörn, Pühler, Alfred, Bendt, A. K., Kramer, R., Burkovski, A.   +12 more
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Proteomic Approaches in the Analysis of Hypertension

2005
The completion of the genomic sequence and the definition of the genes provide a wealth of data to interpret cellular protein expression patterns and relate them to protein function. Proteomics is the large-scale study of proteins in the post-genomic era, aimed at identifying and characterizing protein expression, function, posttranslational ...
Naaby-Hansen, S, Warnasuriya, GD, Hastie, C, Gallney, P, Cramer, R   +4 more
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InterPro and Proteome Analysis — In silico Analysis of Proteins and Proteomes

2004
In the current silicon era of science and technology, scientists at large are no longer concerned with single gene analysis. The rapid appearance of completely sequenced genomes has shifted the focus of research in different ways. For the bench scientist concerned with single or small sets of genes, the focus has widened to include context information.
Nicola Jane Mulder, Manuela Pruess, Rolf Apweiler   +2 more
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Proteome Analysis

Diabetologie Und Stoffwechsel, 2017
Chronic kidney diseases are characterized by a slow progressive loss of renal function leading to kidney failure. At end-stage renal disease, affected patients require renal replacement therapy, dialysis or kidney transplantation, with considerable consequences for mortality and quality of life of the patients.
Drube, Jens, Zuerbig, Petra, Beige, Joachim, Mischak, Harald, Jankowski, Joachim   +4 more
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Trans-Proteomic Pipeline: A Pipeline for Proteomic Analysis

2009
Mass spectrometry has quickly become an essential tool in molecular biology laboratories. Here, we describe the Trans-Proteomic Pipeline, a collection of software tools, to facilitate the analysis, exchange, and comparison of MS data. The pipeline is instrument-independent and supports most commonly used proteomics workflows, including quantitative ...
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Analysis of proteomes—I

2023
Rakeeb Ahmad Mir, Sheikh Mansoor Shafi, Sajad Majeed Zargar   +2 more
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Proteomic Analysis of Brain Mitochondrial Proteome and Mitochondrial Complexes

2013
We describe various complementary techniques to achieve multidimensional mitochondrial proteome fractionation and analysis. Previously described methods for 2D-DIGE/mass spectrometry and 1D-SDS-PAGE/Western techniques and protein complex analysis by BN-PAGE/Western and sucrose gradient ultracentrifugation/SDS-PAGE/mass spectrometry are optimized to ...
Ana, Lopez-Campistrous, Carlos, Fernandez-Patron   +1 more
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