Results 31 to 40 of about 428,393 (307)

Toxicological Analysis in Tissues Following Exhumation More Than Two Years after Death (948 Days): A Forensic Perspective in a Fatal Case

open access: yesToxics, 2023
Exhumations are performed in accordance with a court order and are crucial instruments in the investigation of death allegations. When a death is thought to be the result of drug misuse, pharmaceutical overdose, or pesticide poisoning, this process may ...
Giuseppe Davide Albano   +7 more
doaj   +1 more source

Analysis of the Composition of Deinagkistrodon acutus Snake Venom Based on Proteomics, and Its Antithrombotic Activity and Toxicity Studies

open access: yesMolecules, 2022
There is a strong correlation between the composition of Deinagkistrodon acutus venom proteins and their potential pharmacological effects. The proteomic analysis revealed 103 proteins identified through label-free proteomics from 30 different snake ...
Jin Huang   +4 more
doaj   +1 more source

Revealing nascent proteomics in signaling pathways and cell differentiation. [PDF]

open access: yes, 2018
Regulation of gene expression at the level of protein synthesis is a crucial element in driving how the genetic landscape is expressed. However, we are still limited in technologies that can quantitatively capture the immediate proteomic changes that ...
Burlingame, Alma L   +8 more
core   +1 more source

Salivary proteomic profile of young healthy subjects

open access: yesFrontiers in Molecular Biosciences, 2023
Background: The incidence of noncommunicable diseases (NCDs) has been rapidly ramped up worldwide. Hence, there is an urgent need to non-invasively detect NCDs possibly by exploiting saliva as a ‘liquid biopsy’ to identify biomarkers of the health status.
P. Dongiovanni   +21 more
doaj   +1 more source

Study of protein expresion [sic] in peri-infarct tissue after cerebral ischemia [PDF]

open access: yes, 2015
In this work, we report our study of protein expression in rat peri-infarct tissue, 48 h after the induction of permanent focal cerebral ischemia. Two proteomic approaches, gel electrophoresis with mass spectrometry and combined fractional diagonal ...
Agulla, Jesús   +9 more
core   +5 more sources

Identification of new biomarkers of hepatic cancer stem cells through proteomic profiling [PDF]

open access: yesJournal of Liver Cancer
Backgrounds/Aims In hepatocellular carcinoma (HCC), which exhibits high mortality and recurrence rates globally, the traits of cancer stem cells (CSCs) that significantly influence recurrence and metastasis are not well understood. CSCs are self-renewing
Sung Hoon Choi   +7 more
doaj   +1 more source

Quantitative Proteomic Analysis of Duck Embryo Fibroblasts Infected With Novel Duck Reovirus

open access: yesFrontiers in Veterinary Science, 2020
The novel duck reovirus (NDRV) can cause hemorrhage and necrosis on the spleen of Pekin ducks; this disease has resulted in great economic losses to the duck industry. However, the molecular pathogenesis of NDRV remains poorly understood.
Yudong Yang   +9 more
doaj   +1 more source

Understanding the molecular basis of resilience to Alzheimer’s disease

open access: yesFrontiers in Neuroscience, 2023
The cellular and molecular distinction between brain aging and neurodegenerative disease begins to blur in the oldest old. Approximately 15–25% of observations in humans do not fit predicted clinical manifestations, likely the result of suppressed damage
Kathleen S. Montine   +12 more
doaj   +1 more source

Proteomic analysis of anti-angiogenic effects by conbercept in the mice with oxygen induced retinopathy [PDF]

open access: yesInternational Journal of Ophthalmology, 2020
AIM: To analyze the retinal proteomes with and without conbercept treatments in mice with oxygen-induced retinopathy (OIR) and identify proteins involved in the molecular mechanisms mediated by conbercept.
Ji Jin   +3 more
doaj   +1 more source

Single‐cell proteomic analysis

open access: yesWIREs Mechanisms of Disease, 2020
AbstractThe ability to comprehensively profile proteins in every individual cell of complex biological systems is crucial to advance our understanding of normal physiology and disease pathogenesis. Conventional bulk cell experiments mask the cell heterogeneity in the population, while the single‐cell imaging methods suffer from the limited multiplexing
Thai Pham   +3 more
openaire   +3 more sources

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